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Visualization and Analysis of Parkinson’s Disease Status and Therapy Patterns

  • Anita ValmarskaEmail author
  • Dragana Miljkovic
  • Marko Robnik–Šikonja
  • Nada Lavrač
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 11198)

Abstract

Parkinson’s disease is a neurodegenerative disease affecting people worldwide. Since the reasons for Parkinson’s disease are still unknown and currently there is no cure for the disease, the management of the disease is directed towards handling of the underlying symptoms with antiparkinson medications. In this paper, we present a method for visualization of the patients’ overall status and their antiparkinson medications therapy. The purpose of the proposed visualization method is multi-fold: understanding the clinicians’ decisions for therapy modifications, identification of the underlying guidelines for management of Parkinson’s disease, as well as identifying treatment differences between groups of patients. The resulting patterns of disease progression show that there are differences between male and female patients.

Keywords

Data mining Parkinson’s disease Disease progression Therapy modifications Visualization 

Notes

Acknowledgments

This work was supported by the PD_manager project, funded within the EU Framework Programme for Research and Innovation Horizon 2020 grant 643706. We acknowledge also the support of the Slovenian Research Agency (research core funding program P2-0103 and project P2-0209).

Data used in the preparation of this article were obtained from the Parkinsons Progression Markers Initiative (PPMI) (www.ppmi-info.org/data). For up-to-date information on the study, visit www.ppmi-info.org. PPMI—a public-private partnership—is funded by the Michael J. Fox Foundation for Parkinson’s Research and funding partners. Corporate Funding Partners: AbbVie, Avid Radiopharmaceuticals, Biogen, BioLegend, Bristol-Myers Squibb, GE Healthcare, GLAXOSMITHKLINE (GSK), Eli Lilly and Company, Lundbeck, Merck, Meso Scale Discovery (MSD), Pfizer Inc, Piramal Imaging, Roche, Sanofi Genzyme, Servier, Takeda, Teva, UCB. Philanthropic Funding Partners: Golub Capital. List of funding partners can be also found at www.ppmi-info.org/fundingpartners.

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Copyright information

© Springer Nature Switzerland AG 2018

Authors and Affiliations

  • Anita Valmarska
    • 1
    Email author
  • Dragana Miljkovic
    • 1
  • Marko Robnik–Šikonja
    • 3
  • Nada Lavrač
    • 1
    • 2
    • 4
  1. 1.Jožef Stefan InstituteLjubljanaSlovenia
  2. 2.Jožef Stefan International Postgraduate SchoolLjubljanaSlovenia
  3. 3.Faculty of Computer and Information ScienceUniversity of LjubljanaLjubljanaSlovenia
  4. 4.University of Nova GoricaNova GoricaSlovenia

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