Amyloid-β PET Imaging in Aging and Dementia

  • Nelleke TolboomEmail author
  • Rik Ossenkoppele
  • Bart N. van Berckel
Part of the Clinicians’ Guides to Radionuclide Hybrid Imaging book series (CGRHI)


Amyloid-β imaging with positron emission tomography (PET) has been around since the early 2000s. It has transformed neuroimaging in Alzheimer’s disease (AD) by facilitating in vivo detection (and quantification) of amyloid-β plaques, one of the core pathological features of AD [1]. Initially, it was primarily used for research purposes and only infrequently in clinical practice. Now, more than a decade after the initial publications, it has become a standard diagnostic aid in specialised memory clinics.


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Nelleke Tolboom
    • 1
    Email author
  • Rik Ossenkoppele
    • 2
    • 3
  • Bart N. van Berckel
    • 4
  1. 1.Imaging Division, Department of RadiologyUniversity Medical Center UtrechtUtrechtThe Netherlands
  2. 2.Alzheimer CenterAmsterdam University Medical CenterAmsterdamThe Netherlands
  3. 3.Clinical Memory Research UnitLund UniversityLundSweden
  4. 4.Department of Radiology and Nuclear MedicineAmsterdam University Medical CenterAmsterdamThe Netherlands

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