Umbilical Cord Stem Cells in the Treatment of Corneal Diseases

  • Mohammed Ziaei
  • Jie ZhangEmail author
  • Dipika V. Patel
  • Charles N. J. McGhee
Part of the Essentials in Ophthalmology book series (ESSENTIALS)


To restore transparency and function, corneal specialists currently utilise stem cells of different origins, bioengineered cells and biomaterials. Stem cells are capable of giving rise to progenies with specific functional and morphological traits and in recent years, extraordinary advances have initiated an era of hope for clinical regenerative strategies and tissue engineering applications. In this chapter, we provide an overview of the potential benefits of human umbilical cord derived stem cell therapy and briefly review current approaches to utilize human umbilical cord stem cells to treat diseases involving the corneal epithelium, stroma, and endothelium.


Human umbilical cord stem cells Mesenchymal stem cells Tissue regeneration, stem cell therapy Cornea Transplantation 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Mohammed Ziaei
    • 1
  • Jie Zhang
    • 1
    Email author
  • Dipika V. Patel
    • 1
  • Charles N. J. McGhee
    • 1
  1. 1.Department of OphthalmologyNew Zealand National Eye Centre, Faculty of Medical and Health Sciences, The University of AucklandAucklandNew Zealand

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