Skip to main content

Application of Clustering Technique with Kohonen Self-organizing Maps for the Epidemiological Analysis of Leprosy

  • Conference paper
  • First Online:
Intelligent Systems and Applications (IntelliSys 2018)

Abstract

Leprosy is still a worldwide public health problem, and Brazil ranks second in the largest number of cases of leprosy. Social and economic conditions drastically influence people’s lives, making them more vulnerable to disease and increasing dissemination, contributing to endemicity in the country. Based on this, this study aimed to analyze the epidemiology of leprosy by analyzing data from patients and their Household contacts using Artificial Intelligence techniques in the data mining process. The best results were obtained with Kohonen’s Self-Organizing Maps algorithm in 2 × 3 matrix. A data set with SINAN patients and new leprosy cases (schoolchildren and HHCs) was found in an active search conducted in the municipality of Santarém in the year 2014. The results analyzed call attention to a high number of late diagnoses and the values ​​found for the Anti PGL-1 in clusters 1, 2 and 5 indicating a high burden of the leprosy bacillus and, therefore, a high risk of contagion. The study demonstrated that the identification of the relationship profile of the leprosy patient with their home and their family appears as promising tools, such as leprosy control strategy.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Brasil, Health Surveillance Guide. 2014

    Google Scholar 

  2. de Andrade, L., Sabroza, P.C., de Araújo, A.J.: Factors associated with household and family in leprosy transmission in Rio de Janeiro, Brazil. Cad. Saúde Pública 10(2), 281–292 (1994)

    Article  Google Scholar 

  3. Rocha, C.A.: Characterization of the household contacts in a reference outpatient clinic for Hanseniase in the City of Salvador-Bahia (2016)

    Google Scholar 

  4. Chanteau, S., Glaziou, P., Plichart, C., Luquiaud, P., Plichart, R., Faucher, J.F.: Low predictive value of PGL-I serology for the early diagnosis of leprosy in family contacts: results of a 10-year prospective field study in French Polynesia. Int. J. Lepr. 61(4), 533–541 (1993)

    Google Scholar 

  5. Barreto, J.G., et al.: High rates of undiagnosed leprosy and subclinical infection amongst school children in the Amazon Region High anti-phenolic glycolipid-I IgM titers and hidden leprosy cases, Amazon region. Mem. Inst. Oswaldo Cruz 107(Suppl. 1999), 60–67 (2012)

    Article  Google Scholar 

  6. Gomes, G.P.: Community health agents as facilitators in the identification process of leprosy patients using spatial analysis (2016)

    Google Scholar 

  7. Castro, S.S., Abreu, G.B., Fernandes, L.F.R.M., Santos, J.P.P., Oliveira, V.R.: Leprosy incidence, characterization of cases and correlation with household and cases variables of the Brazilian states in 2010. An. Bras. Dermatol. 91(1), 28–33 (2016)

    Article  Google Scholar 

  8. Araujo, A.E., et al.: Factors associated with neural alterations and physical disabilities in patients with leprosy in São Luis, State of maranhão, Brazil. Rev. Soc. Bras. Med. Trop. 47(4), 490–497 (2014)

    Article  Google Scholar 

  9. Araujo, S., et al.: Unveiling healthy carriers and subclinical infections among household contacts of leprosy patients who play potential roles in the disease chain of transmission. Mem. Inst. Oswaldo Cruz 107(Suppl.1), 55–59 (2012)

    Article  Google Scholar 

  10. Neto, J.M., Carvalho, H.T., Cunha, L.S., Cassenote, A.F., Lozano, A.W., Martins, A.P.: Analysis of control household contacts of people affected by leprosy in brazil and the state of São Paulo de 1991 a 2012. Hansenol. Int. 38, 68–78 (2014)

    Google Scholar 

  11. World Health Organization (WHO): Weekly epidemiological record. 92(17), 205–228 (2017)

    Google Scholar 

  12. Sinan/SVS-MS: General detection rate of leprosy per 100,000 inhabitants. States and regions, Brazil, 1990 to 2016, p. 2017 (2017)

    Google Scholar 

  13. Frade, M.A., et al.: Unexpectedly high leprosy seroprevalence detected using a random surveillance strategy in midwestern Brazil: a comparison of ELISA and a rapid diagnostic test. PLoS Negl. Trop. Dis. 11(2), 1–12 (2017)

    Article  Google Scholar 

  14. Lastória, J.C., Abreu, M.M.: Leprosy: A review of laboratory and therapeutic aspects—part 2. An. Bras. Dermatol. 89(3), 389–401 (2014)

    Article  Google Scholar 

  15. Moura, R.S., Calado, K.L., Oliveira, M.L., Buhrer-Sékula, S.: Leprosy serology using PGL-I: a systematic review. Rev. Soc. Bras. Med. Trop. 41(Suplemento II), 11–18 (2008)

    Article  Google Scholar 

  16. Hand, D.J., Smyth, P., Mannila, H.: Principles of data mining. MIT Press, Cambridge (2001)

    Google Scholar 

  17. Webber, Zat, D.: Use of clustering algorithms in the educational data mining. Rev. Novas Tecnol. na Educ. 11(1679–1916), 1–10 (2013)

    Google Scholar 

  18. Garner, S.R.: Weka: the Waikato environment for knowledge analysis. In: Proceedings of New Zealand Computer Science Research Students Conference, pp. 57–64 (1995)

    Google Scholar 

  19. Nogueira, A., Ferreira, M., Conde, G., Salgado, C., Barreto, J., Conde, M.: Development of a computational system in mobile devices for the optimization of the process of collection, management and analysis of data related to leprosy patients in the West of the State of Pará—Brazil. Hansenol. Int. 39(Suppl 1), 71 (2014)

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Ygor Eugênio Dutra da Silva .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2019 Springer Nature Switzerland AG

About this paper

Check for updates. Verify currency and authenticity via CrossMark

Cite this paper

da Silva, Y.E.D., Salgado, C.G., Conde, V.M.G., Conde, G.A.B. (2019). Application of Clustering Technique with Kohonen Self-organizing Maps for the Epidemiological Analysis of Leprosy. In: Arai, K., Kapoor, S., Bhatia, R. (eds) Intelligent Systems and Applications. IntelliSys 2018. Advances in Intelligent Systems and Computing, vol 869. Springer, Cham. https://doi.org/10.1007/978-3-030-01057-7_24

Download citation

Publish with us

Policies and ethics