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Single Molecule Imaging Using X-ray Free Electron Lasers

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Abstract

The potential to image single molecules in action with a resolution sufficiently high to reveal atomic information at room temperature without the need for crystallization is one of the most exciting applications of X-ray free electron lasers. Significant progress has been made towards this goal over the past years. Here we discuss the current status and describe the steps still required to realize atomic resolution X-ray single particle imaging.

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Authors and Affiliations

  1. Linac Coherent Light Source, SLAC National Accelerator Laboratory, Menlo Park, CA, USA

    Andrew Aquila

  2. Centre for Free-Electron Laser Science, DESY, Hamburg, Germany

    Anton Barty

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  1. Andrew Aquila
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  2. Anton Barty
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Correspondence to Anton Barty .

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  1. SLAC National Accelerator Laboratory, Menlo Park, CA, USA

    Sébastien Boutet

  2. School of Molecular Sciences, Arizona State University, Tempe, AZ, USA

    Petra Fromme

  3. SLAC National Accelerator Laboratory, Menlo Park, CA, USA

    Mark S. Hunter

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Aquila, A., Barty, A. (2018). Single Molecule Imaging Using X-ray Free Electron Lasers. In: Boutet, S., Fromme, P., Hunter, M. (eds) X-ray Free Electron Lasers. Springer, Cham. https://doi.org/10.1007/978-3-030-00551-1_14

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