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Hypertension and vessels

  • Chapter
The Pathology of Vessels

Abstract

Arterial hypertension is commonly classified as primary (essential) or secondary. Two clinical forms occur; by far the most common is a chronic or slowly developing elevation of the blood pressure leading to structural and functional changes in vessels, mediated primarily by vascular smooth muscle [1]. The aetiology is complex and depends on the interaction of a number of genetic factors and events during development, with environmental factors playing a part in some populations [2]. Information on genetic factors (genes coding for renin, angiotensin converting enzyme, angiotensinogen and the AT1 receptor) is well reviewed by Peters [3] and Morgan et al [4] have investigated the significance of polymorphism in the angiotensinogen gene.

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Vuong, P.N., Berry, C. (2002). Hypertension and vessels. In: The Pathology of Vessels. Springer, Paris. https://doi.org/10.1007/978-2-8178-0786-7_16

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  • DOI: https://doi.org/10.1007/978-2-8178-0786-7_16

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