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Clinical relevance of drug resistance: Where do we stand now and where are we going to ?

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Abstract

While chemotherapy can cure several tumours even in advanced stages, like testicular cancer, several cancers of childhood and some haematological malignancies, and can prolonge survival in a number of other malignancies, relapse is often inevitable in the majority of patients due to the occurrence of drug resistance to a broad variety of antineoplastic agents [1]. Drug resistance can be intrinsic or acquired. The former refers to tumours which are initially unresponsive to chemotherapy. Acquired drug resistance develops in a responsive tumour during treatment.

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© 1994 Springer-Verlag France

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Linn, S.C., Giaccone, G., Pinedo, H.M. (1994). Clinical relevance of drug resistance: Where do we stand now and where are we going to ?. In: Banzet, P., Holland, J.F., Khayat, D., Weil, M. (eds) Cancer Treatment An Update. Springer, Paris. https://doi.org/10.1007/978-2-8178-0765-2_5

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  • DOI: https://doi.org/10.1007/978-2-8178-0765-2_5

  • Publisher Name: Springer, Paris

  • Print ISBN: 978-2-8178-0767-6

  • Online ISBN: 978-2-8178-0765-2

  • eBook Packages: Springer Book Archive

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