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Midterm and Long-Term Impacts of GnRH Agonists Treatments

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Early Puberty

Abstract

GnRH analogs treatment is effective on final height, especially when treatment is started before the age of 6 years old.On average, the BMI of girls with precocious puberty treated with GnRH analogs is higher than the BMI of girls from the general population. However, large variability is reported in the literature.GnRH analogs treatment does not seem to alter final postpubertal bone maturation.GnRH analogs treatment does not seem to alter fertility of men and women treated during their infancy.Few data have been reported concerning psychological evaluations of children treated during their infancy by GnRH analog treatment for precocious puberty.

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Authors and Affiliations

  1. Reproductive Endocrine Unit, Hôpital Saint-Antoine, AP-HP, Faculté Pierre et Marie Curie, Paris, 75012, France

    C. Chao & S. Christin-Maitre

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  1. C. Chao
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  2. S. Christin-Maitre
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Editors and Affiliations

  1. Le Kremlin-Bicêtre, France

    Claire Bouvattier

  2. Toulouse CX 09, France

    Catherine Pienkowski

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Chao, C., Christin-Maitre, S. (2016). Midterm and Long-Term Impacts of GnRH Agonists Treatments. In: Bouvattier, C., Pienkowski, C. (eds) Early Puberty. Springer, Paris. https://doi.org/10.1007/978-2-8178-0543-6_8

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  • DOI: https://doi.org/10.1007/978-2-8178-0543-6_8

  • Publisher Name: Springer, Paris

  • Print ISBN: 978-2-8178-0542-9

  • Online ISBN: 978-2-8178-0543-6

  • eBook Packages: MedicineMedicine (R0)

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