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Résumé

La DREZotomie est le nom donné à l’ensemble des interventions effectuées dans la zone s’étendant de la terminaison des racines postérieures aux cornes postérieures de la moelle et comprenant les voies sensitives périphériques, les « 2es neurones » stratifiés en couche et différentes voies centrales activatrices et inhibitrices qui contrôlent ces neurones. En 1972, Sindou a été le précurseur de cette chirurgie en effectuant la première radicellotomie sélective [1]. Basée sur des travaux anatomiques, cette intervention avait pour objectif d’interrompre les fibres nociceptives de petit diamètre dans le cadre du traitement des douleurs de cancer comme le syndrome de Pancoast. Sindou va aussi opérer des patients présentant des douleurs neuropathiques, mais c’est Nashold qui, en 1975, présente les premiers résultats obtenus dans les douleurs d’avulsion du plexus brachial par thermocoagulation des cornes postérieures de la moelle dans une publication intitulée « Focal destruction of substantia gelatinosa of Rolando » [2]. Un seul terme, la DREZotomie, a été retenu pour identifier ces deux interventions qui sont pourtant bien différentes. L’une porte sur les voies terminales du neurone sensitif périphérique alors que l’autre consiste à détruire sur le versant central les 2es neurones désafférentés à l’origine de douleurs neuropathiques. Ces deux interventions, destruction des cornes postérieures et radicellotomie sélective, doivent être étudiées séparément car la technique opératoire et surtout les indications leur sont propres (Fig. 1).

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Références

  1. Sindou M (2009) Surgical dorsal root entry zone lesions for pain. In: Lozano AM, Gildenberg PL, Tasker RR (ed). Textbook of Stereotactic and Functional Neurosurgery, vol 1. Berlin, Heidelberg, p 2269

    Google Scholar 

  2. Nashold BS Jr, et al. (1976) Phantom pain relief by focal destruction of the substantia gelatinosa of Rolando. Adv Pain Res Ther 1: 953–955

    Google Scholar 

  3. Thiébaut JB, Wrobel J, et al. (2010) Les douleurs d’avulsion du plexus brachial. La Lettre de l’Institut UPSA de la douleur, n° 32

    Google Scholar 

  4. Htut M, Misra P, Anand P, et al. (2006) Pain phenomena and sensory recovery following brachial plexus avulsion injury and surgical repairs. J Hand Surg Br 31(6): 596–605

    Article  CAS  PubMed  Google Scholar 

  5. Ramachandran VS, Rogers-Ramachandran D (2000) Phantom limbs and neural plasticity. Arch Neurol 57(3): 317–20

    Article  CAS  PubMed  Google Scholar 

  6. Nashold BS Jr, Pearlstein RD (1994) The DREZ Operation. The American Association of Neurological Surgeons Publications Committee, p 223

    Google Scholar 

  7. Sindou M (2009) Surgical dorsal root entry zone lesions for pain. In: Lozano AM, Gildenberg PL, Tasker RR (ed). Textbook of Stereotactic and Functional Neurosurgery, vol 1. Berlin, Heidelberg, p 2269

    Google Scholar 

  8. Dreval ON (1993) Ultrasonic DREZ-operations for treatment of pain due to brachial plexus avulsion. Acta Neurochir (Wien) 122(1–2): 76–81

    Article  CAS  Google Scholar 

  9. Stranjalis G, Torrens M (1997) Dorsal root entry zone lesion performed with Nd:YAG laser. Br J Neurosurg 11(3): 238–40

    Article  CAS  PubMed  Google Scholar 

  10. Samii M, Bear-Henney S, Lüdemann W, et al. (2001) Treatment of refractory pain after brachial plexus avulsion with dorsal root entry zone lesions. Neurosurgery 48(6): 1269–75; discussion 1275–7

    CAS  PubMed  Google Scholar 

  11. Thomas DG, Kitchen ND (1994) Long-term follow up of dorsal root entry zone lesions in brachial plexus avulsion. J Neurol Neurosurg Psychiatry 57(6): 737–8

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  12. Awad AJ, Forbes JA, Jermakowicz W, et al. (2013) Experience with 25 years of dorsal root entry zone lesioning at a single institution. Surg Neurol Int 4: 64

    Article  PubMed Central  PubMed  Google Scholar 

  13. Tomycz ND, Moossy JJ (2011) Follow-up 26 years after dorsal root entry zone thermocoagulation for brachial plexus avulsion and phantom limb pain. J Neurosurg 114(1): 196–9

    Article  PubMed  Google Scholar 

  14. Aichaoui F, Mertens P, Sindou M (2011) Dorsal root entry zone lesioning for pain after brachial plexus avulsion: results with special emphasis on differential effects on the paroxysmal versus the continuous components. A prospective study in a 29-patient consecutive series. Pain 152(8): 1923–30

    Article  PubMed  Google Scholar 

  15. Lam CR (1936) Nerve injury of fracture of the pelvis. Annals of Surgery 104(5): 945–951

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  16. D’Hardemare V, Silhouette B, et al. (2013) Douleurs par avulsion du plexus lombosacré (APLS). Traitement par DREZotomie au niveau du cône médullaire ou baclofène intrathécal. Résultats à long terme — Congrès de la Société française de neurochirurgie. Bordeaux, 20–23 mars, p 39

    Google Scholar 

  17. Chun HJ, Kim YS, Yi HJ (2011) A modified microsurgical DREZotomy procedure for refractory neuropathic pain. World Neurosurg 75(3–4): 551–7

    Article  PubMed  Google Scholar 

  18. Mehta S, Orenczuk K, McIntyre A, et al. (2013) Neuropathic pain post spinal cord injury part 2: systematic review of dorsal root entry zone procedure. Top Spinal Cord Inj Rehabil 19(1): 78–86

    Article  PubMed Central  PubMed  Google Scholar 

  19. Sindou M (2011) Surgery in the DREZ for refractory neuropathic pain after spinal cord/ cauda equina injury. World Neurosurg 75(3–4): 447–8

    Article  PubMed  Google Scholar 

  20. Spaic M, Markovic N, Tadic R (2002) Microsurgical DREZotomy for pain of spinal cord and Cauda equina injury origin: clinical characteristics of pain and implications for surgery in a series of 26 patients. Acta Neurochir (Wien) 144(5): 453–62

    Article  CAS  Google Scholar 

  21. Rath SA, Seitz K, Soliman N, et al. (1997) DREZ coagulations for deafferentation pain related to spinal and peripheral nerve lesions: indication and results of 79 consecutive procedures. Stereotact Funct Neurosurg 68(1–4 Pt 1): 161–7

    Article  CAS  PubMed  Google Scholar 

  22. Gadgil N, Viswanathan A (2012) DREZotomy in the treatment of cancer pain: a review. Stereotact Funct Neurosurg 90(6): 356–60

    Article  PubMed  Google Scholar 

  23. Bozkurt M, Canbay S, Neves GF, et al. (2012) Microsurgical anatomy of the dorsal thoracic rootlets and dorsal root entry zones. Acta Neurochir (Wien) 154(7): 1235–9

    Article  Google Scholar 

  24. Falci S, Best L, Bayles R, et al. (2002) Dorsal root entry zone microcoagulation for spinal cord injury-related central pain: operative intramedullary electrophysiological guidance and clinical outcome. J Neurosurg 97(2 Suppl): 193–200

    PubMed  Google Scholar 

  25. Giraux P, Sirigu A (2003) Illusory movements of the paralyzed limb restore motor cortex activity. Neuroimage 20(Suppl 1): S107–11

    Article  PubMed  Google Scholar 

  26. Raffin E, Mattout J, Reilly KT, Giraux P (2012) Disentangling motor execution from motor imagery with the phantom limb. Brain 135(Pt 2): 582–95

    Article  PubMed  Google Scholar 

  27. Sindou MP, Mertens P, Bendavid U, et al. (2003) Predictive Value of Somatosensory Evoked Potentials for Long-lasting Pain Relief after Spinal Cord Stimulation: Practical Use for Patient Selection. Neurosurgery 52(6): 1374–84

    Article  PubMed  Google Scholar 

  28. Brill S, Aryeh IG (2008) Neuromodulation in the management of pain from brachial plexus injury. Pain Physician 11(1): 81–5

    PubMed  Google Scholar 

  29. Ali M, Saitoh Y, Oshino S, et al. (2011) Differential Efficacy of Electrical Motor Cortex Stimulation and Lesioning of the Dorsal Root Entry Zone for Continuous versus Paroxysmal Pain after Brachial Plexus Avulsion. Neurosurgery 68(5): 1252–7

    PubMed  Google Scholar 

  30. Margot-Duclot A, Silhouette B, et al. (2010) Intrathecal baclofen for intractable neuropathic pain - Predictive study of efficacy and long term results. Eur J Pain suppl 4(1): 104

    Article  Google Scholar 

  31. Loeser JD, Ward AA Jr, White LE (1968) Chronic deafferentation of human spinal cord neurons. J Neurosurg 29(1): 48–50

    Article  CAS  PubMed  Google Scholar 

  32. Guenot M, Bullier J, Rospars JP, et al. (2003) Single-unit analysis of the spinal dorsal horn in patients with neuropathic pain. J Clin Neurophysiol 20(2): 143–50

    Article  PubMed  Google Scholar 

  33. Lombard MC, Nashold BS Jr, Albe-Fessard D, et al. (1979) Deafferentation hypersensitivity in the rat after dorsal rhizotomy: a possible animal model of chronic pain. Pain 6(2): 163–74

    Article  CAS  PubMed  Google Scholar 

  34. Rinaldi PC, Young RF, Albe-Fessard D, Chodakiewitz J(1991) Spontaneous neuronal hyperactivity in the medial and intralaminar thalamic nuclei of patients with deafferentation pain. J Neurosurg 74(3): 415–21

    Article  CAS  PubMed  Google Scholar 

  35. Rampin O, Morain P (1987) Cortical involvement in dorsal horn cell hyperactivity and abnormal behavior in rats with dorsal root section. Somatosens Res 4(3): 237–51

    Article  CAS  PubMed  Google Scholar 

  36. North RB, Levy RM (1994) Consensus conference on the neurosurgical management of pain. Neurosurgery 34(4): 756–60; discussion 760–1

    Article  CAS  PubMed  Google Scholar 

  37. Cetas JS, Saedi T, Burchiel KJ (2008) Destructive procedures for the treatment of nonmalignant pain: a structured literature review. J Neurosurg 109(3): 389–404

    Article  PubMed  Google Scholar 

  38. Bullard DE, Nashold BS, Jr (1997) The caudalis DREZ for facial pain. Stereotact Funct Neurosurg 68(1–4 Pt 1): 168–74

    Article  CAS  PubMed  Google Scholar 

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Thiébaut, JB., d’Hardemare, V., Margot-Duclot, A., Silhouette, B. (2014). DREZotomie. In: Chirurgie de la douleur. Springer, Paris. https://doi.org/10.1007/978-2-8178-0509-2_35

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  • DOI: https://doi.org/10.1007/978-2-8178-0509-2_35

  • Publisher Name: Springer, Paris

  • Print ISBN: 978-2-8178-0508-5

  • Online ISBN: 978-2-8178-0509-2

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