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Transperineal Template-guided Mapping Biopsy of the Prostate

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Technical Aspects of Focal Therapy in Localized Prostate Cancer

Abstract

This chapter presents the role of transperineal template-guided mapping biopsy (TTMB) in determining management strategy in patients with low-risk prostate cancer (PCa). TTMB is an effective procedure for detecting PCa in patients who have had previous negative biopsies and a high suspicion of cancer. TTMB shows prostate cancer in one-third of such patients. TTMB is also used to help select patients for prostate cancer management. The Transatlantic Consensus Group on Active Surveillance and Focal Therapy for Prostate Cancer recommends emerging detecting tools such as new imaging techniques and transperineal mapping biopsies to improve prostate cancer management.

TTMB was shown to be optimal for detecting clinically significant PCa when compared with other available biopsy options. The transperineal approach allows longitudinal access to the prostate gland and a more accurate sampling, especially on the peripheral anterior and apical part of the gland. Of all biopsy-related complications, 19 % are associated with TTMB; most of them were mild and transient complications.

TTMB is a useful resource in clinical practice for several reasons. Over 30 % of patients had been understaged after the initial extended biopsy. In addition, the information these biopsies provide helps to properly select the best candidates for active surveillance programs, focal therapy, or radical therapy. The fusion of advanced imaging guidance with TTMB will be an interesting advance in prostate cancer diagnosis and can potentially overcome most of the shortcomings of present biopsy techniques.

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Author information

Authors and Affiliations

  1. Department of Urology, St. John’s Medical College, Bangalore, India

    Rafael Sanchez-Salas

  2. Department of Urology, Institut Montsouris, Paris, France

    Arjun Sivaraman

Authors
  1. Arjun Sivaraman
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  2. Rafael Sanchez-Salas
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Correspondence to Rafael Sanchez-Salas .

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Editors and Affiliations

  1. Department of Urology, Institut Montsouris, Paris-Descartes University, Paris, France

    Eric Barret

  2. Department of Urology, Hôpital Pasteur 2 – Centre Hospitalier Universitaire de Nice, Antipolis, France

    Matthieu Durand

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Sivaraman, A., Sanchez-Salas, R. (2015). Transperineal Template-guided Mapping Biopsy of the Prostate. In: Barret, E., Durand, M. (eds) Technical Aspects of Focal Therapy in Localized Prostate Cancer. Springer, Paris. https://doi.org/10.1007/978-2-8178-0484-2_10

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  • DOI: https://doi.org/10.1007/978-2-8178-0484-2_10

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  • Publisher Name: Springer, Paris

  • Print ISBN: 978-2-8178-0483-5

  • Online ISBN: 978-2-8178-0484-2

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