Skip to main content

Choc hémorragique et stratégie transfusionnelle

  • Chapter
Réanimation pédiatrique

Part of the book series: Le point sur … ((POINT))

  • 1105 Accesses

Résumé

Le choc est défini comme un déséquilibre entre la consommation d’oxygène (VO2) et les apports en oxygène (O2) de la cellule. Dans le choc hémorragique, il résulte d’une perte aiguë de sang par le compartiment intravasculaire. Un choc hémorragique peut survenir dans diverses circonstances : à domicile (ex. hémorragie digestive profuse chez un malade ayant des varices oesophagiennes), sur les lieux d’un accident, en milieu hospitalier (ex. phase postopératoire d’amygdalectomie) ou en réanimation, chez un enfant admis pour un autre motif (ex. hémorragie digestive acquise chez un traumatisé crânien grave). Les traumatismes constituent la cause la plus fréquente de choc hémorragique en pédiatrie [1]. La rapidité d’intervention est cruciale pour la survie.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Références

  1. Orliaguet G, Gauvin F, Hume H et al. (2007) Choc hémorragique. In: Lacroix J, Gauthier M, Hubert P, Leclerc F, Gaudreault P (eds) Urgences et soins intensifs pédiatriques. Éditions du CHU Sainte-Justine et Elsevier-Masson Montréal, pp 167–186

    Google Scholar 

  2. Rasmussen GE, Grande CM (1994) Blood, fluids, and electrolytes in the pediatric trauma patient. Int Anesthesiol Clin 32: 79–101

    PubMed  CAS  Google Scholar 

  3. Sazama K (1990) Reports of 355 transfusion-associated deaths: 1976 through 1985. Transfusion 30: 583–90

    Article  PubMed  CAS  Google Scholar 

  4. Callum JL, Pinkerton PH (2003) Bloody easy: Blood transfusions; Blood alternatives and transfusion reactions; A guide to transfusion medicine. Savattuq Inc Toronto, Ontario

    Google Scholar 

  5. Kleinman S, Chan P, Robillard P (2003) Risks associated with transfusion of cellular blood components in Canada. Transfus Med Rev 17: 120–62

    PubMed  Google Scholar 

  6. Popovsky MA (2001) Transfusion reactions. AABB Press Bethesda, Maryland

    Google Scholar 

  7. Silliman CC, Boshkov LK, Mehdizadehkashi Z et al. (2003) Transfusion-related acute lung injury: Epidemiology and a prospective analysis of etiologic factors. Blood 101: 454–62

    Article  PubMed  CAS  Google Scholar 

  8. Toy P, Popovsky MA, Abraham E et al. (2005) Transfusion-related acute lung injury: definition and review. Crit Care Med 33: 721–6

    Article  PubMed  Google Scholar 

  9. Laupacis A, Brown J, Costello B et al. (2001) Prevention of posttransfusion CMV in the era of universal WBC reduction: A consensus statement. Transfusion 41: 560–9

    Article  PubMed  CAS  Google Scholar 

  10. Preiksaitis JK (2000) The cytomegalovirus “safe” blood product: Is leukoreduction equivalent to antibody screening? Transfus Med Rev 14: 112–36

    Article  PubMed  CAS  Google Scholar 

  11. MacDonald NE, Giulivi A, for the Canadian Paediatric Society (2003) Transfusion and risk of infection in Canada. Paediatr Child Health 8: 135–7

    Google Scholar 

  12. Llewelyn CA, Hewitt PE, Knight RS et al. (2004) Possible transmission of variant Creutzfeldt-Jakob disease by blood transfusion. Lancet 363: 417–21

    Article  PubMed  CAS  Google Scholar 

  13. Pillonel J, Laperche S (2004) [Trends in residual risk of transfusion-transmitted viral infections (HIV, HCV, HBV) in France between 1992 and 2002 and impact of viral genome screening (Nucleic Acid Testing)]. Transfus Clin Biol 11: 81–6

    Article  PubMed  CAS  Google Scholar 

  14. Webb IJ, Anderson KC (2001) Transfusion-associated graft vs host disease. In: Popovsky MA (ed) Transfusion reactions. AABB Press Bethesda, Maryland, p 171–86

    Google Scholar 

  15. McFarland JG (2001) Posttransfusion purpura. In: Popovsky MA (ed) Transfusion reactions. AABB Press Bethesda, Maryland, p 187–212

    Google Scholar 

  16. Harvey MP, Greenfield TP, Sugrue ME et al. (1995) Massive blood transfusion in a tertiary referral hospital. Clinical outcomes and haemostatic complications. Med J Aust 163: 356–9

    CAS  Google Scholar 

  17. Ricci B, Calogero G (1988) Oxygen-induced retinopathy in newborn rats: Effects of prolonged normobaric and hyperbaric oxygen supplementation. Pediatrics 82: 193–8

    PubMed  CAS  Google Scholar 

  18. Kanter RK, Zimmerman JJ, Strauss RH et al. (1986) Pediatric emergency intravenous access. Evaluation of a protocol. Am J Dis Child 140: 132–4

    CAS  Google Scholar 

  19. Perel P, Roberts I (2012) Colloids versus crystalloids for fluid resuscitation in critically ill patients. Cochrane Database Syst Rev: CD000567

    Google Scholar 

  20. Spinella PC, Holcomb JB (2009) Resuscitation and transfusion principles for traumatic hemorrhagic shock. Blood Rev 23: 231–40

    Article  PubMed  Google Scholar 

  21. Finfer S, Bellomo R, Boyce N et al. (2004) A comparison of albumin and saline for fluid resuscitation in the intensive care unit. N Engl J Med 350: 2247–56

    Article  PubMed  CAS  Google Scholar 

  22. Boldt J (2004) Fluid choice for resuscitation of the trauma patient: A review of the physiological, pharmacological, and clinical evidence. Can J Anaesth 51: 500–13

    Article  PubMed  Google Scholar 

  23. Soderlind M, Salvignol G, Izard P et al. (2001) Use of albumin, blood transfusion and intraoperative glucose by APA and ADARPEF members: A postal survey. Paediatr Anaesth 11: 685–9

    Article  PubMed  CAS  Google Scholar 

  24. Schierhout G, Roberts I (1998) Fluid resuscitation with colloid or crystalloid solutions in critically ill patients: A systematic review of randomised trials. BMJ 316: 961–4

    Article  PubMed  CAS  Google Scholar 

  25. Velanovich V (1989) Crystalloid versus colloid fluid resuscitation: A meta-analysis of mortality. Surgery 105: 65–71

    PubMed  CAS  Google Scholar 

  26. Choi PT, Yip G, Quinonez LG et al. (1999) Crystalloids vs colloids in fluid resuscitation: A systematic review. Crit Care Med 27: 200–10

    Article  PubMed  CAS  Google Scholar 

  27. Roberts P, Alderson P, Bunn F et al. (2004) Colloids versus crystalloids for fluid resuscitation in critically ill patients (Cochrane Review). The Cochrane Library. John Wiley & Sons Ltd. Oxford

    Google Scholar 

  28. Wilkes MM, Navickis RJ (2001) Patient survival after human albumin administration. A meta-analysis of randomized, controlled trials. Ann Intern Med 135: 149–64

    Article  CAS  Google Scholar 

  29. Ngo NT, Cao XT, Kneen R et al. (2001) Acute management of dengue shock syndrome: A randomized double-blind comparison of 4 intravenous fluid regimens in the first hour. Clin Infect Dis 32: 204–13

    Article  PubMed  CAS  Google Scholar 

  30. Paul M, Dueck M, Joachim Herrmann H et al. (2003) A randomized, controlled study of fluid management in infants and toddlers during surgery: Hydroxyethyl starch 6 % (HES 70/0.5) vs lactated Ringer’s solution. Paediatr Anaesth 13: 603–8

    Article  PubMed  Google Scholar 

  31. Wills BA, Nguyen MD, Ha TL et al. (2005) Comparison of three fluid solutions for resuscitation in dengue shock syndrome. N Engl J Med 353: 877–89

    Article  PubMed  Google Scholar 

  32. Bunn F, Trivedi D, Ashraf S (2008) Colloid solutions for fluid resuscitation. Cochrane Database Syst Rev: CD001319

    Google Scholar 

  33. Chong Sung K, Kum Suk P, Mi Ja Y et al. (2006) Effects of intravascular volume therapy using hydroxyethyl starch (130/0.4) on post-operative bleeding and transfusion requirements in children undergoing cardiac surgery: a randomized clinical trial. Acta Anaesthesiol Scand 50: 108–11

    Article  PubMed  CAS  Google Scholar 

  34. Kozek-Langenecker S, Scharbert G (2008) Comparing the effects of colloids on clot formation. Anaesthesia 63: 673–4; author reply 674

    Article  PubMed  CAS  Google Scholar 

  35. Kozek-Langenecker SA, Jungheinrich C, Sauermann W et al. (2008) The effects of hydroxyethyl starch 130/0.4 (6 %) on blood loss and use of blood products in major surgery: a pooled analysis of randomized clinical trials. Anesth Analg 107: 382–90

    Article  PubMed  CAS  Google Scholar 

  36. Liet JM, Kuster A, Denizot S et al. (2006) Effects of hydroxyethyl starch on cardiac output in hypotensive neonates: a comparison with isotonic saline and 5 % albumin. Acta Paediatr 95: 555–60

    Article  PubMed  Google Scholar 

  37. Standl T, Lochbuehler H, Galli C et al. (2008) HES 130/0.4 (Voluven) or human albumin in children younger than 2 yr undergoing non-cardiac surgery. A prospective, randomized, open label, multicentre trial. Eur J Anaesthesiol 25: 437–45

    Article  CAS  Google Scholar 

  38. Sumpelmann R, Kretz FJ, Gabler R et al. (2008) Hydroxyethyl starch 130/0.42/6:1 for perioperative plasma volume replacement in children: preliminary results of a European Prospective Multicenter Observational Postauthorization Safety Study (PASS). Paediatr Anaesth 18: 929–33

    Article  PubMed  Google Scholar 

  39. Vincent JL, Navickis RJ, Wilkes MM (2004) Morbidity in hospitalized patients receiving human albumin: A meta-analysis of randomized, controlled trials. Crit Care Med 32: 2029–38

    Article  PubMed  CAS  Google Scholar 

  40. Vermeulen LC, Ratko TA, Erstad BL et al. (1995) A paradigm for consensus. The University Hospital Consortium guidelines for the use of albumin, nonprotein colloid, and crystalloid solutions. Arch Intern Med 155: 373–9

    Google Scholar 

  41. Rivers E, Nguyen B, Havstad S et al. (2001) Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 345: 1368–77

    Article  PubMed  CAS  Google Scholar 

  42. Duchesne JC, Hunt JP, Wahl G et al. (2008) Review of current blood transfusions strategies in a mature level I trauma center: were we wrong for the last 60 years? J Trauma 65: 272–6; discussion 276-8

    Article  PubMed  Google Scholar 

  43. Sperry JL, Ochoa JB, Gunn SR et al. (2008) An FFP: PRBC transfusion ratio >/=1:1.5 is associated with a lower risk of mortality after massive transfusion. J Trauma 65: 986–93

    Article  PubMed  Google Scholar 

  44. Teixeira PG, Inaba K, Shulman I et al. (2009) Impact of plasma transfusion in massively transfused trauma patients. J Trauma 66: 693–7

    Article  PubMed  Google Scholar 

  45. Holcomb JB, Wade CE, Michalek JE et al. (2008) Increased plasma and platelet to red blood cell ratios improves outcome in 466 massively transfused civilian trauma patients. Ann Surg 248: 447–58

    PubMed  Google Scholar 

  46. Durand P, Chevret L, Essouri S et al. (2008) Respiratory variations in aortic blood flow predict fluid responsiveness in ventilated children. Intensive Care Med 34: 888–94

    Article  PubMed  Google Scholar 

  47. Knottenbelt JD (1991) Low initial hemoglobin levels in trauma patients: An important indicator of ongoing hemorrhage. J Trauma 31: 1396–9

    Article  PubMed  CAS  Google Scholar 

  48. Nordin A, Makisalo H, Hockerstedt K (1994) Dopamine infusion during resuscitation of experimental hemorrhagic shock. Crit Care Med 22: 151–6

    PubMed  CAS  Google Scholar 

  49. Poloujadoff MP, Borron SW, Amathieu R et al. (2007) Improved survival after resuscitation with norepinephrine in a murine model of uncontrolled hemorrhagic shock. Anesthesiology 107: 591–6

    Article  PubMed  CAS  Google Scholar 

  50. Grounds M (2003) Recombinant factor VIIa (rFVIIa) and its use in severe bleeding in surgery and trauma: A review. Blood Rev 17 Suppl 1: S11–21

    Article  PubMed  Google Scholar 

  51. Tobias JD (2002) Synthetic factor VIIa to treat dilutional coagulopathy during posterior spinal fusion in two children. Anesthesiology 96: 1522–5

    Article  PubMed  Google Scholar 

  52. Morenski JD, Tobias JD, Jimenez DF (2003) Recombinant activated factor VII for cerebral injury-induced coagulopathy in pediatric patients. Report of three cases and review of the literature. J Neurosurg 98: 611–6

    Google Scholar 

  53. Uhrig L, Blanot S, Baugnon T et al. (2007) Use of recombinant activated factor VII in intractable bleeding during pediatric neurosurgical procedures. Pediatr Crit Care Med 8: 576–9

    Article  Google Scholar 

  54. Vamvakas EC (2004) White blood cell-containing allogeneic blood transfusion, postoperative infection and mortality: A meta-analysis of observational ‘before and after’ studies. Vox Sang 86: 111–9

    Article  PubMed  CAS  Google Scholar 

  55. Dzik WH, Anderson JK, O’Neill EM et al. (2002) A prospective, randomized clinical trial of universal WBC reduction. Transfusion 42: 1114–22

    Article  PubMed  CAS  Google Scholar 

  56. Bilgin YM, van de Watering LM, Eijsman L et al. (2004) Double-blind, randomized controlled trial on the effect of leukocyte-depleted erythrocyte transfusions in cardiac valve surgery. Circulation 109: 2755–60

    Article  PubMed  CAS  Google Scholar 

  57. van Hilten JA, van de Watering LM, van Bockel JH et al. (2004) Effects of transfusion with red cells filtered to remove leucocytes: Randomised controlled trial in patients undergoing major surgery. BMJ 328: 1281

    Article  PubMed  Google Scholar 

  58. Hurtaud MF (1990) Physiologie et exploration de l’hémostase chez l’enfant. Feuillet de biologie 31: 41–46

    Google Scholar 

  59. Tibby SM, Murdoch IA (2003) Monitoring cardiac function in intensive care. Arch Dis Child 88: 46–52

    Article  PubMed  CAS  Google Scholar 

  60. Laverdière C, Gauvin F, Hébert PC et al. (2002) Survey of transfusion practices in pediatric intensive care units. Pediatr Crit Care Med 3: 335–40

    Article  PubMed  Google Scholar 

  61. Nahum E, Ben-Ari J, Schonfeld T (2004) Blood transfusion policy among European pediatric intensive care physicians. J Intensive Care Med 19: 38–43

    Article  PubMed  Google Scholar 

  62. Gauvin F, Chaïbou M, Leteurtre S et al. (2000) Pratique de transfusion de concentré globulaire en réanimation pédiatrique: une étude descriptive prospective. Réanimation Urgences 9: 339–44

    Article  Google Scholar 

  63. Armano R, Gauvin F, Ducruet T et al. (2005) Determinants of red blood cell transfusions in a pediatric critical care unit: a prospective, descriptive epidemiological study. Crit Care Med 33: 2637–44

    Article  PubMed  Google Scholar 

  64. Carson JL, Noveck H, Berlin JA et al. (2002) Mortality and morbidity in patients with very low postoperative Hb levels who decline blood transfusion. Transfusion 42: 812–8

    Article  PubMed  Google Scholar 

  65. Lackritz EM, Campbell CC, Ruebush TK et al. (1992) Effect of blood transfusion on survival among children in a Kenyan hospital. Lancet 340: 524–8

    Article  PubMed  CAS  Google Scholar 

  66. English M, Ahmed M, Ngando C et al. (2002) Blood transfusion for severe anaemia in children in a Kenyan hospital. Lancet 359: 494–5

    Article  PubMed  Google Scholar 

  67. Lacroix J, Hebert PC, Hutchison JS et al. (2007) Transfusion strategies for patients in pediatric intensive care units. N Engl J Med 356: 1609–19

    Article  PubMed  CAS  Google Scholar 

  68. Surgenor SD, Hampers MJ, Corwin HL (2001) Is blood transfusion good for the heart? Crit Care Med 29: 442–4

    Article  PubMed  CAS  Google Scholar 

  69. Hill SR, Carless PA, Henry DA et al. (2002) Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion (Cochrane Review. The Cochrane Library. Update Software Oxford

    Google Scholar 

  70. Morris KP, Naqvi N, Lee PW et al. (2000) Calculating blood transfusion volume in critically ill children. Pediatr Crit Care Med 1

    Google Scholar 

  71. Davies P, Robertson S, Hegde S et al. (2007) Calculating the required transfusion volume in children. Transfusion 47: 212–6

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to G. Orliaguet .

Rights and permissions

Reprints and permissions

Copyright information

© 2013 Springer-Verlag Paris

About this chapter

Cite this chapter

Orliaguet, G. (2013). Choc hémorragique et stratégie transfusionnelle. In: Réanimation pédiatrique. Le point sur …. Springer, Paris. https://doi.org/10.1007/978-2-8178-0407-1_2

Download citation

  • DOI: https://doi.org/10.1007/978-2-8178-0407-1_2

  • Publisher Name: Springer, Paris

  • Print ISBN: 978-2-8178-0406-4

  • Online ISBN: 978-2-8178-0407-1

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics