Abstract
The adipose tissue plays an important role in the toxicokinetics of Persistent Organic Pollutants. This tissue may have a protective function in case of acute or subacute exposure: it can take up these pollutants and thereby prevent their localization in other more sensitive tissues. In the long run, the adipose tissue constitutes an endogenous source of chronic low-grade exposure. This is revealed in case of weight loss. The adipose tissue is also a target of toxicants which alter signaling pathways, differentiation programs and induce inflammation.
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Barouki, R., Clément, K. (2013). The Adipose Tissue: Storage, Source, and Target of Pollutants. In: Bastard, JP., Fève, B. (eds) Physiology and Physiopathology of Adipose Tissue. Springer, Paris. https://doi.org/10.1007/978-2-8178-0343-2_11
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DOI: https://doi.org/10.1007/978-2-8178-0343-2_11
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