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Intoxications graves par la théophylline

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Part of the book series: Références en réanimation. Collection de la SRLF ((SRLF))

Résumé

L’intoxication par la théophylline a remarquablement augmenté ces dernières années, et ce, en raison de sa large prescription ainsi que l’introduction de la forme à libération prolongée [1]. Elle touche préférentiellement les sujets de sexe féminin. Les intoxications graves peuvent aboutir au décès ; la mortalité rapportée est de 0,6 %, et est essentiellement liée aux complications cardiaques et neurologiques [1, 2, 3].

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Références

  1. Shannon M (1999) Life threatening events after theophylline overdose. Arch Intern Med 83: 219–26

    Google Scholar 

  2. Parr M, Anaes F, Day A, et al. (1990) Theophylline poisoning. Intensive Care Medicine 16: 394–98

    Article  PubMed  CAS  Google Scholar 

  3. Sessler C (1990) Theophylline Toxicity. Am J Med 88: 567–76

    Article  PubMed  CAS  Google Scholar 

  4. Gaudreault P, Guay J (1986) Theophylline poisoning: Pharmacological considerations and clinical management. Medical Toxicology 1: 169–91

    PubMed  CAS  Google Scholar 

  5. Shannon M, Maher T (1995) Anticonvulsant effects of intracerebroventricular Adenocard in theophylline-induced seizures. Ann Emerg Med 26: 65–8

    Article  PubMed  CAS  Google Scholar 

  6. Henderson JH, McKenzie CA, Hilton PJ, Leach RM (2001) Continuous venovenous haemofiltration for the treatment of theophylline toxicity. Thorax 56: 242–43

    Article  PubMed  CAS  Google Scholar 

  7. Ujhelyi MR, Hulula G, Skkau DA (1994) Role of exogenous adenosine as a modulator of theophylline toxicity. Crit Care Med 22: 1639–46

    PubMed  CAS  Google Scholar 

  8. Yarnell PR (1975) Focal seizures and aminophylline. Neurology 25: 819–22

    Article  PubMed  CAS  Google Scholar 

  9. Shannon M (1994) Hypokaliema, hyperglycemia and plasma cathecolamines activity after severe theophylline intoxication. Clinical Toxicology 32: 41–7

    Article  PubMed  CAS  Google Scholar 

  10. Charytan D, Jansen K (2003) Severe metabolic complications from theophylline intoxication. Nephrology 8(5): 239–42

    Article  PubMed  Google Scholar 

  11. Tweleit S, Hippius M, Pfeifer R, Hoffman A (2001) Rhabdomyolysis as a rare complication of theophylline poisoning. Med Klin 96: 40–4

    Article  Google Scholar 

  12. Szymanowicz A, Danel V (2005) Biomarqueurs de toxicité dans les principales intoxications graves. Immuno-analyse et Biologie spécialisée 20: 144–60

    Article  Google Scholar 

  13. Minton NA, Henry JA (1996) Treatment of theophylline overdose. Am J Emerg Med 14: 606–12

    Article  PubMed  CAS  Google Scholar 

  14. Amin DJ, Henry JA (1985) Propranolol administration in theophylline overdose. Lancet 1: 520–21

    Article  PubMed  CAS  Google Scholar 

  15. Chyka PA, Seger D (1997) Position statement: single-dose activated charcoal. American Academy of Clinical Toxicology, European Association of Poisons Centres and Clinica Toxicologists. J Toxicol Clin Toxicol 35: 721–25

    CAS  Google Scholar 

  16. Chyka PA, Holley JE, Mandrell T, Sugathan PS (1995) Correlation of drug pharmacokinetics and effectiveness of multiple dose activated charcoal therapy. Ann Emerg Med 25: 356–62

    Article  PubMed  CAS  Google Scholar 

  17. Shannon M (1997) Comparative Efficacy of hemodialysis and hemoperfusion in sever theophylline intoxication. Acad Emerg Med 4: 674–78

    Article  PubMed  CAS  Google Scholar 

  18. Sen S, Ytrebo LM, Rose C et al. (2004) Albumin dialysis: a new therapeutic strategy for intoxication from protein-bound drugs. Intensive Care Med 30: 496–501

    Article  PubMed  Google Scholar 

  19. Korsheed S, Selby NM, Fluck R (2007) Treatment of severe theophylline poisoning with the molecular adsorbent recirculating (MARS). Nephrol Dial Transplant 22: 969–70

    Article  PubMed  Google Scholar 

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Correspondence to N. Brahmi .

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Brahmi, N., Thabet, H., Elghord, H., Kouraichi, N., Amamou, M. (2013). Intoxications graves par la théophylline. In: Intoxications aiguës. Références en réanimation. Collection de la SRLF. Springer, Paris. https://doi.org/10.1007/978-2-8178-0301-2_13

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  • DOI: https://doi.org/10.1007/978-2-8178-0301-2_13

  • Publisher Name: Springer, Paris

  • Print ISBN: 978-2-8178-0300-5

  • Online ISBN: 978-2-8178-0301-2

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