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Le Mid regional proadrenomedullin (MRproADM)

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Les biomarqueurs en médecine d’urgence

Résumé

L’adrénomédulline (ADM) est une hormone découverte au début des années 1990, qui connaît un regain d’intérêt dans le domaine d’application des biomarqueurs. Initialement caractérisée dans les glandes surrénales, l’ADM a été détectée dans de nombreux autres tissus et la circulation systémique. Son activité biologique dépend de sa forme mature. Les propriétés vasomotrices de l’ADM ont suggéré son intérêt potentiel comme témoin de l’équilibre hémodynamique. Récemment, les progrès techniques conduisant au dosage plus stable de la pro-hormone ont permis de mieux étudier et comprendre le rôle de l’ADM dans diverses situations cliniques aigués, et son intérêt comme marqueur de sévérité.

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Claessens, YÉ., Trabattoni, É. (2012). Le Mid regional proadrenomedullin (MRproADM). In: Claessens, YÉ., Ray, P. (eds) Les biomarqueurs en médecine d’urgence. Références en médecine d’urgence. Collection de la SFMU. Springer, Paris. https://doi.org/10.1007/978-2-8178-0297-8_20

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  • DOI: https://doi.org/10.1007/978-2-8178-0297-8_20

  • Publisher Name: Springer, Paris

  • Print ISBN: 978-2-8178-0296-1

  • Online ISBN: 978-2-8178-0297-8

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