Résumé
La prise en charge des cancers du sein, repose toujours en 2011 en France sur, d’une part, les paramètres classiques : taille tumorale, envahissement ganglionnaire, grade histopronostique modifié par Elston Ellis, envahissement lymphatique et, d’autre part, les paramètres « biologiques » que sont les statuts des récepteurs hormonaux et de HER2.
Références
Penault-Llorca F, Arnould L (2010) Adjuvant breast cancer: which clinical and pathological characteristics in 2007? Bull Cancer 97: 1421–1426
Sørlie T, Perou CM, Tibshirani R et al. (2001) Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 98: 10869–10874
Nielsen TO, Hsu FD, Jensen K et al. (2004) Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma. Clin Cancer Res 10: 5367–5374
Ross JS (2009) Multigene classifiers, prognostic factors, and predictors of breast cancer clinical outcome. Adv Anat Pathol 16: 204–215
Lamy PJ, Romieu G, Jacot W (2010) UPA/PAI-1: a tool for breast cancer treatment individualization. Biology, clinical implications and quantification assays. Bull Cancer 97: 341–348
Carlson RW, Allred DC, Anderson BO et al.; NCCN Breast Cancer Clinical Practice Guidelines Panel (2009) Breast cancer. Clinical practice guidelines in oncology. J Natl Compr Canc Netw 7: 122–192
Goldhirsch A, Wood WC, Coates AS, Gelber RD, Thürlimann B, Senn HJ; Panel members (2011) Strategies for subtypes—dealing with the diversity of breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer. Ann Oncol 2011 22: 1736–1747
Recommandations pour la pratique clinique de Saint-Paul-de-Vence (2011) Cancers du sein. Oncologie (in press)
Dowsett M, Salter J, Zabaglo L et al. (2011) Predictive algorithms for adjuvant therapy: TransATAC. Steroids 76: 777–780
Dowsett M, O Nielsen T, A’Hern R et al. (2011) Ki-67 in breast cancer: recommendations from the International Ki-67 in Breast Cancer Working Group JNCI
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Penault-Llorca, F. (2012). Mieux faire que les facteurs histopronostiques classiques TN et grade histopronostique : biochimie et immunohistochimie?. In: Cancer du sein : surdiagnostic, surtraitement. Springer, Paris. https://doi.org/10.1007/978-2-8178-0249-7_18
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DOI: https://doi.org/10.1007/978-2-8178-0249-7_18
Publisher Name: Springer, Paris
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