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Lactate: métabolisme et physiopathologie

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Désordres métaboliques et réanimation

Part of the book series: Le point sur ... ((POINT))

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Résumé

Comprendre la physiopathologie d’une hyperlactatémie passe par une connaissance étroite de son métabolisme. Le métabolisme du lactate est complexe, dépendant des différents organes et de leur condition énergétique. L’hyperlactatémie est depuis longtemps liée à la notion de déchet métabolique toxique, d’acidose lactique et d’hypoxie tissulaire. Toutes ces associations profondément ancrées dans nos esprits sont le plus souvent erronées. L’hyperlactatémie reste un bon signal d’alarme de crise énergétique, mais elle est aussi le témoin d’une adaptation métabolique. Dans certaines situations physiologiques et pathologiques, le lactate est un réel substrat énergétique.

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Authors
  1. J.-C. Orban
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  2. C. Ichai
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  3. X. Leverve
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Orban, JC., Ichai, C., Leverve, X. (2011). Lactate: métabolisme et physiopathologie. In: Désordres métaboliques et réanimation. Le point sur .... Springer, Paris. https://doi.org/10.1007/978-2-287-99027-4_8

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  • DOI: https://doi.org/10.1007/978-2-287-99027-4_8

  • Publisher Name: Springer, Paris

  • Print ISBN: 978-2-287-99026-7

  • Online ISBN: 978-2-287-99027-4

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