Abstract
In 1928, the English physician Edward Carmichael provided the first documented account of cerebellar glioblastoma (GBM) [1]. This tumour localization is uncommon and all but one series [33] have included small numbers (≤ 8 cases; Table 1). No prospective data are available for this tumour localization and cerebellar GBM patients are not eligible in GBM prospective cooperative trials. As such, the radiotherapy techniques for this tumour are ill defined and the outcome of these exceptional patients is somewhat unclear.
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Refrences
Carmichael E (1928) Cerebral gliomata. JPath Bact 31:493–510
Chamberlain MC, Silver P, Levin VA (1990) Poorly differentiated gliomas of the cerebellum. A study of 18 patients. Cancer 65: 337–40
Chang EL, Akyurek S, Avalos T et al. (2007) Evaluation of peritumoral edema in the delineation of radiotherapy clinical target volumes for glioblastoma. Int J Radiat Oncol Biol Phys. 68:144–50
DeAngelis LM (2001) Brain tumors. N Engl J Med 344: 114–23
Demir MK, Hakan T, Akinci O et al. (2005) Primary cerebellar glioblastoma multi-forme. Diagn Interv Radiol. 11: 83–86
Dohrmann GJ, Farwell JR, Flannery JT (1976) Glioblastoma multiforme in children. J Neurosurg 44: 442–8
Fresh CB, Takei Y, O’Brien MS (1976) Cerebellar glioblastoma in childhood. Case report. J Neurosurg. 45: 705–8
Gupta V, Goyal A, Sinha S et al. (2003) Glioblastoma of the cerebellum. A report of 3 cases. J Neurosurg Sci. 47: 157–164; discussion 164-155
Katz DS, Poe LB, Winfield JA et al. (1995) A rare case of cerebellar glioblastoma multiforme in childhood: MR imaging. Clin Imaging 19:162–4
Kopelson G (1982) Cerebellar glioblastoma. Cancer 50: 308–11
Kopelson G, Linggood R (1982) Infratentorial glioblastoma: the role of neuraxis irradiation. Int J Radiat Oncol Biol Phys 8: 999–1003
Kowalczuk A, Macdonald RL, Amidei C et al. (1997) Quantitative imaging study of extent of surgical resection and prognosis of malignant astrocytomas. Neurosurgery. 41: 1028–1036; discussion 1036-1028
Kulkarni AV, Becker LE, Jay V et al. (1999) Primary cerebellar glioblastomas multiforme in children. Report of four cases. J Neurosurg 90: 546–50
Levine S, McKeever P, Greenberg H (1987) Primary cerebellar glioblastoma multi-forme. J Neurooncol 5: 231–6
Mattos JP, Marenco HA, Campos JM et al. (2006) Cerebellar glioblastoma multi-forme in an adult. Arq Neuropsiquiatr 64: 132–5
Meikle SR, Matthews JC, Brock CS et al. (1998) Pharmacokinetic assessment of novel anti-cancer drugs using spectral analysis and positron emission tomography: a feasibility study. Cancer Chemother Pharmacol 42: 183–93
Meis JM, Martz KL, Nelson JS (1991) Mixed glioblastoma multiforme and sarcoma. A clinicopathologic study of 26 radiation therapy oncology group cases. Cancer 67: 2342–9
Newlands ES, O’Reilly SM, Glaser MG et al. (1996) The Charing Cross Hospital experience with temozolomide in patients with gliomas. Eur J Cancer 32A: 2236–41
Nishioka H, Saito F, Haraoka J et al. (1991) [Glioblastoma of the cerebellum: report of an autopsy case associated with intratumoral hemorrhage and CSF seedings]. No Shinkei Geka 19: 547–52
Ostermann S, Csajka C, Buclin T et al. (2004) Plasma and cerebrospinal fluid population pharmacokinetics of temozolomide in malignant glioma patients. Clin Cancer Res 10: 3728–36
Palma L, Celli P, Maleci A et al. (1989) Malignant monstrocellular brain tumours. A study of 42 surgically treated cases. Acta Neurochir (Wien) 97: 17–25
Parsa AT, Wachhorst S, Lamborn KR et al. (2005) Prognostic significance of intracranial dissemination of glioblastoma multiforme in adults. J Neurosurg. 102: 622–8
Pato-Pato A, Cimas-Hernando I, Lorenzo-Gonzalez JR et al. (2004) [Cerebellar glioblastoma multiforme: a case report]. Rev Neurol 38: 839–42
Plowman J, Waud WR, Koutsoukos AD et al. (1994) Preclinical antitumor activity of temozolomide in mice: efficacy against human brain tumor xenografts and synergism with 1,3-bis(2-chloroethyl)-1-nitrosourea. Cancer Res 54: 3793–9
Queiroz LS, Faria AV, Zanardi VA et al. (2005) Lipidized giant-cell glioblastoma of cerebellum. Clin Neuropathol 24: 262–6
Salazar OM, Rubin P (1976) The spread of glioblastoma multiforme as a determining factor in the radiation treated volume. Int J Radiat Oncol Biol Phys 1: 627–37
Salazar OM, Rubin P, McDonald JV et al. (1976) Patterns of failure in intracranial astrocytomas after irradiation: analysis of dose and field factors. AJR Am J Roentgenol 126: 279–92
Sandberg-Wollheim M, Malmstrom P, Stromblad LG et al. (1991) A randomized study of chemotherapy with procarbazine, vincristine, and lomustine with and without radiation therapy for astrocytoma grades 3 and/or 4. Cancer 68: 22–9
Sgouros S, Fineron PW, Hockley AD (1995) Cerebellar astrocytoma of childhood: long-term follow-up. ChildsNerv Syst 11: 89–96
Simpson JR, Horton J, Scott C et al. (1993) Influence of location and extent of surgical resection on survival of patients with glioblastoma multiforme: results of three consecutive Radiation Therapy Oncology Group (RTOG) clinical trials. Int J Radiat Oncol Biol Phys 26: 239–44
Stupp R, Mason WP, van den Bent MJ et al. (2005) Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352: 987–96
Tamaki T, Eguchi T, Sakamoto M et al. (2004) Glioblastoma multiforme of the cerebellum in an elderly man. J Chin Med Assoc 67: 301–4
Weber DC, Miller RC, Villa S et al. (2006) Outcome and prognostic factors in cerebellar glioblastoma multiforme in adults: a retrospective study from the Rare Cancer Network. Int J Radiat Oncol Biol Phys 66: 179–86
Yang S, Wang K, Cho B et al. (2005) Radiation-induced cerebellar glioblastoma at the site of a treated medulloblastoma: case report. J Neurosurg 102: 417–22
Yung WK, Prados MD, Yaya-Tur R et al. (1999) Multicenter phase II trial of temozolomide in patients with anaplastic astrocytoma or anaplastic oligoastrocytoma at first relapse. Temodal Brain Tumor Group. J Clin Oncol 17: 2762–71
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Weber, D.C. (2009). Cerebellar Glioblastoma multiforme. In: Belkacémi, Y., Mirimanoff, RO., Ozsahin, M. (eds) Management of Rare Adult Tumours. Springer, Paris. https://doi.org/10.1007/978-2-287-92246-6_5
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DOI: https://doi.org/10.1007/978-2-287-92246-6_5
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