Abstract
The term “primary breast lymphoma” (PBL) is used to define malignant lymphoma primarily occurring in the breast in the absence of other previously detected lymphoma localizations. The first definition was proposed by Wiseman and Liao in 1972 [49]. The clinical pathological criteria for the definition of PBL include: “the clinical site of presentation is the breast, the absence of disseminated lymphoma or preceding extra-mammary lymphoma at the time of diagnosis, adequate pathological specimen evaluation, histological evidence of a close association between the mammary tissue and the lymphomatous infiltrate, and presence of homolateral axillary lymph nodes that may be involved if they develop simultaneously with the primary breast tumor”.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Abbondanzo SL, Seidman JD, Lefkowitz M et al. (1996) Primary diffuse large B-cell lymphoma of the breast. A clinicopathologic study of 31 cases. Pathol Res Pract 192(1): 37–43
Arber DA, Simpson JF, Weiss LM et al. (1994) Non-Hodgkin’s lymphoma involving the breast. Am J Surg Pathol 18(3): 288–95
Avilés A, Castañeda C, Neri N et al. (2007) Rituximab and dose dense chemotherapy in primary breast lymphoma. Haematologica 92(08): 1147–8.
Avilés A, Delgado S, Nambo MJ et al. (2005) Primary Breast Lymphoma: Results of a Controlled Clinical Trial. Oncology 69: 256–60
Bai M, Agnantis NJ, Skyrlas A et al. (2003) Increased Expression of the bcl6 and CD 10 Proteins Is Associated with Increased Apoptosis and Proliferation in Diffuse Large B-Cell Lymphomas. Mod Pathol 16: 471–80
Baker R, Slayden G, Jennings W et al. (2005) Multifocal primary breast lymphoma. South Med J 98: 1045–8
Bakheet SM, Bakheet R, Ezzat A et al. (2001) F-18 FDG Positron Emission Tomography in Primary Breast Non-Hodgkin’s Lymphoma. Clin Nucl Med 26: 299–301
Barrans SL, Carter I, Owen RG et al. (2002) Germinal center phenotype and bcl-2 expression combined with the International Prognostic Index improves patient risk stratification in diffuse large B-cell lypmphoma. Blood 99: 1136–43
Barrans SL, O’Connor SJ, Evans PA et al. (2002) Rearrangement of the BCL6 locus at 3q27 is an independent poor prognostic factor in nodal diffuse B-cell lymphoma. Br J Haematol 117: 322–32
Bobrow LG, Richards MA, Happerfield LC et al. (1993) Breast lymphomas: a clinicopathologic review. Hum Pathol 24(3): 274–8
Brogi E, Harris NL (1999) Lymphomas of the breast: pathology and clinical behavior. Semin Oncol 26(3): 357–64
Brustein S, Kimmel M, Lieberman PH et al. (1987) Malignant Lymphoma of the Breast. A study of 53 patients. Ann. Surg vol 205(2): 144–50
Carbone PP, Kaplan HS, Musshoff K et al. (1971) Report of the Committee on Hodgkin’s disease staging classification. Cancer Res 31: 1860–1
Coiffier B, Lepage E, Briere J et al. (2002) CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma. N Engl J Med 346: 235–42
Dao AH, Adkins RB Jr, Glick AD et al. (1992) Malignant lymphoma of the breast: a review of 13 cases. Am Surg 58(12): 792–6
Delbeke D (1999) Oncological applications of FDG PET imaging: brain tumors, colorectal cancer, lymphoma and melanoma. J Nucl Med 40: 591
Dixon JM, Lumsden AB, Krajewski A et al. (1987) Primary lymphoma of the breast. Br J Surg 74: 214–6
Domchek SM, Hecht JL, Fleming MD et al. (2002) Lymphomas of the breast. Primary and Secondary Involvement. Cancer 94: 6–13
Duncan VE, Reddy VVB, Jhala NC et al. (2006) Non-Hodgkin’s lymphoma of the breast: a review of 18 primary and secondary cases. Annals of Diagnostic Pathology 10:144–8
Farinha P, Saudade A, Cabecadas J et al. (2000) High frequency of MALT lymphoma in a series of 14 cases of primary breast lymphoma. Appl Immunol Mol Morpho 10: 115–26
Fruchart C, Denoux Y, Chasle J et al. (2005) High grade primary breast lymphoma: is it a different clinical entity? Breast Cancer Research and Treatment 93: 191–8
Ganjoo K, Advani R, Mariappan MR et al. (2007) Non-Hodgkin Lymphoma of the Breast. Cancer 110: 25–30
Giardini R, Piccolo C, Rilke F et al. (1992) Primary non-Hodgkin’s lymphomas of the female breast. Cancer 69(3): 725–35
Gupta D, Shindham V, Zemba-Palko V, Keshgegian A (2000) Primary bilateral mucosa-associated lymphoid tissue lymphoma of the breast with atypical ductal hyperplasia and localized amyloidosis. A case report and review of the literature. Arch Pathol lab Med 124: 1233–6
Ha CS, Dubey P, Goyal LK et al. (1998) Localized Primary Non-Hodgkin Lymphoma of the Breast. Am J Clin Oncol 21(4): 376–80
Horning SJ, Weller E, Kim K et al. (2004) Chemotherapy with or without radiotherapy in limited-stage diffuse aggressive non-Hodgkin’s lymphoma: Eastern Cooperative Oncology group Study 1484. J Clin Oncol 22: 3032–8
Hugh JC, Jackson FI, Hanson J et al. (1990) Primary breast lymphoma. An immunohistologic study of 20 new cases. Cancer 66: 2602–11
The International Non-Hodgkin’s lymphoma Prognostic Factors Project (1993) A predictive Model for aggressive Non-Hodgkin’s Lymphoma.N Engl J Med 329: 987–94
Jeanneret Sozzi W, Taghian A, Epelbaum R et al. (2008) Primary breast lymphoma: Patient profile, outcome and prognostic factors. A multicentre Rare Cancer Network study. BMC Cancer 8: 86
Jennings WC, Baker RS, Murray SS et al. (2007) Primary Breast Lymphoma. The Role of Mastectomy and the Importance of Lymph Node Status. Ann Surg 245: 784–9
Kambouchner M, Godmer P, Guillevin L et al. (2003) Low grade marginal zone B cell lymphoma of the breast associated with localized amyloidosis and corpora amylacea in a woman with long standing primary Sjogren’s syndrome. J Clin Pathol 56: 74–7
Kuper-Hommel MJJ, Snijder S, Janssen-Heijnen MLG et al. (2003) Treatment and survival of 38 female breast lymphomas: a population-based study with clinical and pathological reviews. Ann Hematol 82: 397–404
Lavomec J, Jancar J (1987) Primary malignant lymphoma of the breast: lymphoma of the mucosa-associated lymphoid tissue. Cancer 60: 3033–41
Liberman L, Giess CS, Dershaw DD et al. (1994) Non-Hodgkin Lymphoma of the Breast: Imaging Characteristics and Correlation with Histopathologic Findings. Radiology 192: 157–60
Lin Y, Guo XM, Shen KW et al. (2006) Primary breast lymphoma: Long-term treatment outcome and prognosis. Leukemia & Lymphoma 47(10): 2102–9
Liu MT, Hsieh CY, Wang AY et al. (2005) Primary breast lymphoma: a pooled analysis of prognostic factors and survival in 93 cases. Ann Saudi Med 25(4): 288–93
Lyons JA, Myles J, Pohlman B et al. (2000) Treatment and Prognosis of Primary Breast Lymphoma: A Review of 13 Cases. Am J Clin Oncol 23(4): 334–6.
Lyou CY, Yang SK, Choe DH et al. (2007) Mammographic and sonographic findings of primary breast lymphoma. Clinical Imaging 31: 234–8
Mattia AR, Ferry JA, Harris NL et al. (1993) Breast lymphoma. A B-cell spectrum including the low grade B-cell lymphoma of mucosa associated lymphoid tissue. Am J Surg Pathol 17(6): 574–87
Miller T, Unger J, Spier C et al. (2004) Effect of adding rituximab to three cycles of CHOP plus involved field radiotherapy for limited stage aggressive diffuse large B-cell lymphoma (SWOG-0014) Blood 104: 48a–9a
Miller TP, LeBlanc M, Spier C et al. (2001) CHOP alone compared to CHOP plus radiotherapy for early stage aggressive non-Hogkin’s lymphoma: update of the Southwest Oncology Group (SWOG) randomized trial. Blood 98: 72A
Pfreundschuh M., Trumper L, Osterborg A et al. (2006) CHOP-like chemotherapy plus rituximab versus CHOP-like chemotherapy alone in young patients with good-prognosis diffuse large B-cell lymphoma: a randomized controlled trial by the Mab Thera International Trial (MinT) Group. Lancet Oncol. 7: 379–91
Ribrag V, Bibeau F, El Weshi A et al. (2001) Primary breast lymphoma: a report of 20 cases. British Journal of Haematology 115: 253–6
Ryan G, Martinelli G, Kuper-Hommel M et al. (2008) Primary diffuse large B-cell lymphoma of the breast: prognostic factors and outcomes of a study by the International Extranodal Lymphoma Group. Annals of Oncology 19: 233–41
Sabaté JM, Gómez A, Torrubia S et al. (2002) Lymphoma of the Breast: Clinical and Radiologic Features With Pathologic Correlation in 28 Patients. The Breast Journal 8(5): 294–304
Shouton JT, Weese JL, Carbone P et al (1981) Lymphoma of the breast. Ann Surg 194(69): 749–53
Topalovski M, Crisan D, Mattson JC et al. (1999) Lymphoma of the Breast. A Clinicopathologic Study of Primary and Secondary Cases. Arch Pathol Lab Med 123: 1208–18
Vignot S, Ledoussal V, Nodiot P et al (2005) Non-Hodgkin’s Lymphoma of the Breast: a Report of 19 Cases and Review of the Literature. Clin Lymphoma 6(1): 37–42
Wiseman C, Liao KT (1972) Primary lymphoma of the breast. Cancer 29(6) 1705–12
Wong WW, Schild SE, Halyard MY et al. (2002) Primary Non-Hodgkin Lymphoma of the Breast: The Mayo Clinic Experience. Journal of Surgical Oncology 80: 19–25
Yoshida S, Nakamura N, Sasaki Y et al. (2005) Primary breast diffuse large B-cell lymphoma shows a non-germinal B-cell phenotype. Modern Pathology 18: 398–405
Young SD, Imrie K, Gospodarowicz M et al. (1999) Primary lymphoma of the breast: a 30 year retrospective analysis of the Toronto experience. Proc ASCO 18:41a.
Zack RJ, Trevisan SG, Gupta M et al. (2001) Primary breast lymphoma originating in a benign intramammary lymph node. Am J Roentgenol 177: 177–8
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2009 Springer-Verlag France, Paris
About this chapter
Cite this chapter
Jeanneret Sozzi, W., Mirimanoff, RO. (2009). Primary breast lymphoma. In: Belkacémi, Y., Mirimanoff, RO., Ozsahin, M. (eds) Management of Rare Adult Tumours. Springer, Paris. https://doi.org/10.1007/978-2-287-92246-6_40
Download citation
DOI: https://doi.org/10.1007/978-2-287-92246-6_40
Publisher Name: Springer, Paris
Print ISBN: 978-2-287-92245-9
Online ISBN: 978-2-287-92246-6
eBook Packages: MedicineMedicine (R0)