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Aider á vivre aprés un cancer pp 203–211Cite as

Tumeurs secondaires: l’expérience du cancer du sein

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Part of the book series: Oncologie pratique ((ONCOLPRAT))

Résumé

Les traitements modernes du cancer du sein ont permis une amélioration de la survie á long terme. La chimiothérapie adjuvante et/ou les nouvelles molécules de traitements ciblés ont permis de prolonger la survie sans récidive et la survie globale (1). La radiothérapie adjuvante joue un rôle essentiel dans la prévention des récidives locorégionales du cancer du sein et son effi cacité a été démontrée dans plusieurs essais randomisés, ainsi que dans la méta-analyse (2–9). Dans les formes á haut risque de récidive, cette action locorégionale de la radiothérapie se traduit par un bénéfi ce de survie á long terme (9). Plusieurs techniques d’irradiation de plus en plus améliorées ont été développées (10–13) pour diminuer la toxicité á court et á long terme (14–18). L’hormonothérapie joue également un rôle important dans le traitement de patients présentant des récepteurs á oestrogéne et progestérone positifs (19). L’ensemble de ces traitements est indispensable pour la prise en charge de patientes avec un cancer du sein, mais il peut être responsable de complications á long terme de type tumeurs secondaires. La cancérogenése est multifactorielle: la prédisposition génétique, la chimiothérapie, la radiothérapie, l’hormonothérapie sont connues pour être des facteurs de risque de cancer (14).

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  1. Service d’oncologie-radiothérapie, Institut Curie, 26, rue d’Ulm, 75005, Paris

    Youlia M. Kirova

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Kirova, Y.M. (2010). Tumeurs secondaires: l’expérience du cancer du sein. In: Aider á vivre aprés un cancer. Oncologie pratique. Springer, Paris. https://doi.org/10.1007/978-2-287-79501-5_15

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  • DOI: https://doi.org/10.1007/978-2-287-79501-5_15

  • Publisher Name: Springer, Paris

  • Print ISBN: 978-2-287-79500-8

  • Online ISBN: 978-2-287-79501-5

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