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Trisomie 21

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Épidémiologie des cancers de l’enfant

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Abstrait

La trisomie 21 touche environ une naissance sur 800 et les enfants atteints ont un risque de 10 à 20 fois plus élevé de développer une leucémie que la population générale. En revanche, la survenue de tumeurs solides dans l’enfance et à l’âge adulte semble être moins fréquente, excepté, de façon récurrente dans les différentes études, pour les tumeurs testiculaires et peut-être pour le rétinoblastome (1–8). La fréquence, tant des leucémies que des tumeurs solides, est plus élevée chez le garçon.

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  1. Service de génétique, cologique Institut Curie, 26, rue d’Ulm, 75248, Paris Cedex 05

    Jérôme Couturier

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© 2009 Springer-Verlag France

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Couturier, J. (2009). Trisomie 21. In: Épidémiologie des cancers de l’enfant. Springer, Paris. https://doi.org/10.1007/978-2-287-78337-1_31

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  • DOI: https://doi.org/10.1007/978-2-287-78337-1_31

  • Publisher Name: Springer, Paris

  • Print ISBN: 978-2-287-78336-4

  • Online ISBN: 978-2-287-78337-1

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