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Physiopathologie du DES syndrome

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Le Distilbène® trente ans après

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Abstrait

Les organismes en cours de développement sont particulièrement vulnérables. La prolifération cellulaire rapide, la différenciation cellulaire associées aux phénomènes de migration survenant lors du développement embryonnaire contribuent à cette sensibilité. Le DES traverse la barrière placentaire et induit des anomalies chez le fœtus en cours de développement. Contrairement au thalidomide qui provoque des anomalies réductionnelles immédiatement décelables, les anomalies induites par le DES sont uniquement décelables à long terme.

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Authors and Affiliations

  1. Service de gynécologie-obstétrique, Hôpital de la Conception, 147, boulevard Baille, 13005, Marseille

    F. Bretelle

  2. Service de gynécologie-obstétrique, CHU Michallon, BP 217, 38043, Grenoble Cedex 09

    J. -C. Pons

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  1. F. Bretelle
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© 2007 Springer-Verlag France, Paris

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Bretelle, F., Pons, J.C. (2007). Physiopathologie du DES syndrome . In: Le Distilbène® trente ans après. Springer, Paris. https://doi.org/10.1007/978-2-287-73307-9_2

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  • DOI: https://doi.org/10.1007/978-2-287-73307-9_2

  • Publisher Name: Springer, Paris

  • Print ISBN: 978-2-287-73306-2

  • Online ISBN: 978-2-287-73307-9

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