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Résumé

Le concept de glomérulopathie paranéoplasique a été initialement évoqué par Galloway en 1922, avec l’association d’une maladie de Hodgkin et d’un syndrome néphrotique (1). Après cette première description, de nombreux cas d’association entre cancer et atteinte rénale sont rapportés. Cependant, l’existence d’un lien de causalité entre cancer et atteinte rénale reste discutée (2, 3). La définition même du terme «paranéoplasique» implique une relation temporelle forte entre le symptôme (ou son évolution) et la néoplasie (ou son évolution). S’il existe des cas publiés d’amélioration rapide des paramètres rénaux après prise en charge tumorale (4), et a contrario des cas d’aggravation rénale après récidive néoplasique (5), il existe également des évolutions dissociées (6). Dans ce cas, l’origine paranéoplasique doit être remise en question, même s’il n’existe pas à l’évidence d’autre étiologie à la glomérulopathie.

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Bacchetta, J., Juillard, L., Cochat, P., Droz, JP. (2010). Rénaux. In: Tumeurs malignes rares. Springer, Paris. https://doi.org/10.1007/978-2-287-72070-3_45

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  • DOI: https://doi.org/10.1007/978-2-287-72070-3_45

  • Publisher Name: Springer, Paris

  • Print ISBN: 978-2-287-72069-7

  • Online ISBN: 978-2-287-72070-3

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