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Localisation uro-génitale

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Tumeurs malignes rares

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Résumé

Les lymphomes primitifs du testicule présentent des particularités histologiques, évolutives et pronostiques. Il s’agit le plus souvent de lymphome diffus B à grandes cellules. Ils sont associés à une grande fréquence de récidives extraganglionnaires. Le lymphome du testicule atteint principalement l’adulte âgé mais de rares cas sont décrits chez l’enfant. Son traitement comporte le plus souvent un geste chirurgical diagnostique. La stratégie thérapeutique actuelle associe les protocoles modernes de chimiothérapie des lymphomes incluant le rituximab. Toutefois plusieurs questions se posent concernant la place éventuelle de l’irradiation prophylactique du testicule restant, des aires ganglionnaires de drainage et la place de la prophylaxie cérébrale ainsi que de ses modalités.

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Références

  1. Doll DC, Weiss RB (1986) Malignant lymphoma of the testis. Am J Med 81: 515–24

    Article  CAS  PubMed  Google Scholar 

  2. Shahab N, Doll DC (1999) Testicular lymphoma. Semin Oncol 26: 259–69

    CAS  PubMed  Google Scholar 

  3. Hasselblom S, Ridell B, Wedel H, et al. (2004) Testicular lymphoma:a retrospective, population-based, clinical and immunohistochemical study. Acta Oncol 43: 758–65

    Article  PubMed  Google Scholar 

  4. Lagrange JL, Ramaioli A, Theodore CH, et al. (2001) Non-Hodgkin’s lymphoma of the testis: a retrospective study of 84 patients treated in the French anticancer centres. Ann Oncol 12: 1313–9

    Article  CAS  PubMed  Google Scholar 

  5. Zucca E, Roggero E, Bertoni F, Cavalli F (1997) Primary extranodal non-Hodgkin’s lymphomas. Part 1: Gastrointestinal, cutaneous and genitourinary lymphomas. Ann Oncol 8: 727–37

    Article  CAS  PubMed  Google Scholar 

  6. Buzelin F, Karam G, Moreau A, et al. (1994) Testicular tumor and the acquired immunodeficiency syndrome. Eur Urol 26: 71–6

    CAS  PubMed  Google Scholar 

  7. Zucca E, Conconi A, Mughal TI, et al. (2003) Patterns of outcome and prognostic factors in primary large-cell lymphoma of the testis in a survey by the International Extranodal Lymphoma Study Group. J Clin Oncol 21: 20–7

    Article  CAS  PubMed  Google Scholar 

  8. Meignan M, Haioun C, Itti E, et al. (2006) Value of [18F] fluorodeoxyglucose-positron emission tomography in managing patients with aggressive non-Hodgkin’s lymphoma. Clin Lymphoma Myeloma 6: 306–13

    Article  PubMed  Google Scholar 

  9. Fonseca R, Habermann TM, Colgan JP, et al. (2000) Testicular lymphoma is associated with a high incidence of extranodal recurrence. Cancer 88: 154–61

    Article  CAS  PubMed  Google Scholar 

  10. Al-Abbadi MA, Hattab EM, Tarawneh MS, et al. (2006) Primary testicular diffuse large B-cell lymphoma belongs to the nongerminal center B-cell-like subgroup: a study of 18 cases. Mod Pathol 19: 1521–7

    Article  CAS  PubMed  Google Scholar 

  11. Ferry JA, Harris NL, Young RH, et al. (1994) Malignant lymphoma of the testis, epididymis, and spermatic cord. A clinicopathologic study of 69 cases with immunophenotypic analysis. Am J Surg Pathol 18: 376–90

    Article  CAS  PubMed  Google Scholar 

  12. Hans CP, Weisenburger DD, Greiner TC, et al. (2004) Confirmation of the molecular classification of diffuse large B-cell lymphoma by immunohistochemistry using a tissue microarray. Blood 103: 275–82

    Article  CAS  PubMed  Google Scholar 

  13. Ridell B, Norrby K (2001) Intratumoral microvascular density in malignant lymphomas of B-cell origin. APMIS 109: 66–72

    Article  CAS  PubMed  Google Scholar 

  14. Miller TP, Dahlberg S, Cassady JR, et al. (1998) Chemotherapy alone compared with chemotherapy plus radiotherapy for localized intermediate-and high-grade non-Hodgkin’s lymphoma. N Engl J Med 339: 21–6

    Article  CAS  PubMed  Google Scholar 

  15. Feugier P, Van Hoof A, Sebban C, et al. (2005) Long-term results of the R-CHOP study in the treatment of elderly patients with diffuse large B-cell lymphoma: a study by the Groupe d’étude des Lymphomes de l’Adulte. J Clin Oncol 23: 4117–26

    Article  CAS  PubMed  Google Scholar 

  16. Habermann TM, Weller EA, Morrison VA, et al. (2006) Rituximab-CHOP versus CHOP alone or with maintenance rituximab in older patients with diffuse large B-cell lymphoma. J Clin Oncol 24: 3121–7

    Article  CAS  PubMed  Google Scholar 

  17. Pfreundschuh M, Schubert J, Ziepert M, et al. (2008) Six versus eight cycles of bi-weekly CHOP-14 with or without rituximab in elderly patients with aggressive CD20+ B-cell lymphomas: a randomised controlled trial (RICOVER-60). Lancet Oncol 9: 105–16

    Article  CAS  PubMed  Google Scholar 

  18. Coiffier B, Lepage E, Briere J, et al. (2002) CHOP chemotherapy plus rituximab compared with CHOP alone in elderly patients with diffuse large-B-cell lymphoma. N Engl J Med 346: 235–42

    Article  CAS  PubMed  Google Scholar 

  19. Ballonoff A, Rusthoven KE, Schwer A, et al. (2008) Outcomes and Effect of Radiotherapy in Patients with Stage I or II Diffuse Large B-Cell Lymphoma: A Surveillance, Epidemiology, and End Results Analysis. Int J Radiat Oncol Biol Phys 72: 1465–71

    Article  PubMed  Google Scholar 

  20. Haioun C, Besson C, Lepage E, et al. (2000) Incidence and risk factors of central nervous system relapse in histologicallyaggressive non-Hodgkin’s lymphoma uniformly treated and receiving intrathecal central nervous system prophylaxis: a GELA study on 974 patients. Groupe d’Etudes des Lymphomes de l’Adulte. Ann Oncol 11: 685–90

    Article  CAS  PubMed  Google Scholar 

  21. Feugier P, Virion JM, Tilly H, et al. (2004) Incidence and risk factors for central nervous system occurrence in elderly patients with diffuse large-B-cell lymphoma: influence of rituximab. Ann Oncol 15: 129–33

    Article  CAS  PubMed  Google Scholar 

  22. Phillips SM, Ferry DR, Lee SJ (1994) Carcinoma of the prostate mimicking lymphoma. Br J Urol 73: 590–1

    Article  CAS  PubMed  Google Scholar 

  23. Bostwick DG, Iczkowski KA, Amin MB, et al. (1998) Malignant lymphoma involving the prostate: report of 62 cases. Cancer 83: 732–8

    Article  CAS  PubMed  Google Scholar 

  24. Bostwick DG, Mann RB (1985) Malignant lymphomas involving the prostate. A study of 13 cases. Cancer 56: 2932–8

    Article  CAS  PubMed  Google Scholar 

  25. Chu PG, Huang Q, Weiss LM (2005) Incidental and concurrent malignant lymphomas discovered at the time of prostatectomy and prostate biopsy: a study of 29 cases. Am J Surg Pathol 29: 693–9

    Article  PubMed  Google Scholar 

  26. Eisenberger CF, Walsh PC, Eisenberger MA, et al. (1999) Incidental non-Hodgkin’s lymphoma in patients with localized prostate cancer. Urology 53: 175–9

    Article  CAS  PubMed  Google Scholar 

  27. Fukutani K, Koyama Y, Fujimori M, Ishida T (2003) Primary malignant lymphoma of the prostate: report of a case achieving complete response to combination chemotherapy and review of 22 Japanese cases. Nippon Hinyokika Gakkai Zasshi 94: 621–5

    PubMed  Google Scholar 

  28. Freeman C, Berg JW, Cutler SJ (1972) Occurrence and prognosis of extranodal lymphomas. Cancer 29: 252–60

    Article  CAS  PubMed  Google Scholar 

  29. Kempton CL, Kurtin PJ, Inwards DJ, et al. (1997) Malignant lymphoma of the bladder: evidence from 36 cases that low-grade lymphoma of the MALT-type is the most common primary bladder lymphoma. Am J Surg Pathol 21: 1324–33

    Article  CAS  PubMed  Google Scholar 

  30. Bates AW, Norton AJ, Baithun SI (2000) Malignant lymphoma of the urinary bladder: a clinicopathological study of 11 cases. J Clin Pathol 53: 458–61

    Article  CAS  PubMed  Google Scholar 

  31. Hughes M, Morrison A, Jackson R (2005) Primary bladder lymphoma: management and outcome of 12 patients with a review of the literature. Leuk Lymphoma 46: 873–7

    Article  PubMed  Google Scholar 

  32. Okuno SH, Hoyer JD, Ristow K, Witzig TE (1995) Primary renal non-Hodgkin’s lymphoma. An unusual extranodal site. Cancer 75: 2258–61

    Article  CAS  PubMed  Google Scholar 

  33. Stallone G, Infante B, Manno C, et al. (2000) Primary renal lymphoma does exist: case report and review of the literature. J Nephrol 13: 367–72

    CAS  PubMed  Google Scholar 

  34. Dauchy FA, Etienne G, Deminiere C, et al. (2006) Lymphoma with initial renal involvement: about four cases. Rev Med Interne 27: 909–915

    Article  PubMed  Google Scholar 

  35. Cupisti A, Riccioni R, Carulli G, et al. (2004) Bilateral primary renal lymphoma treated by surgery and chemotherapy. Nephrol Dial Transplant 19: 1629–33

    Article  PubMed  Google Scholar 

  36. Choi JH, Choi GB, Shim KN, et al. (1997) Bilateral primary renal non-Hodgkin’s lymphoma presenting with acute renal failure: successful treatment with systemic chemotherapy. Acta Haematol 97: 231–5

    Article  CAS  PubMed  Google Scholar 

  37. Diskin CJ, Stokes TJ, Dansby LM, et al. (2007) Acute renal failure due to a primary renal B-cell lymphoma. Am J Kidney Dis 50: 885–9

    Article  PubMed  Google Scholar 

  38. Tokar M, Rogachev B, Levi I, et al. (2004) Rituximab in a patient with acute renal failure due to B-cell lymphomatous infiltration of the kidneys. Leuk Lymphoma 45: 819–20

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Service de radiothérapie Assistance Publique-Hôpitaux de Paris Hôpital Henri-Mondor, Université Paris XII, 51, avenue du Maréchal-de-Lattre-de-Tassigny, 94000, Créteil

    Jean -Léon Lagrange

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Lagrange, J.L. (2010). Localisation uro-génitale. In: Tumeurs malignes rares. Springer, Paris. https://doi.org/10.1007/978-2-287-72070-3_11

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  • DOI: https://doi.org/10.1007/978-2-287-72070-3_11

  • Publisher Name: Springer, Paris

  • Print ISBN: 978-2-287-72069-7

  • Online ISBN: 978-2-287-72070-3

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