Abstract
“ A group of overlapping disorders with different aetiologies but similar biologic, morphologic and clinical outcomes. The disease processes affect articular cartilage, subchondral bone, synovium, capsule and ligaments. Ultimately, cartilage degenerates with fibrillation, fissures, ulceration and full thickness loss of joint surface. ”Nigel ArdenThis definition is itself developed from one coined by the Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association for the development of criteria for classifying and reporting osteoarthritis in 1986 [1]. It also made the distinction between subclinical, non-symptomatic defects in articular cartilage, which is poorly innervated, and the clinical syndrome, which includes pain, that may develop from such defects [1].
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Cooper, C., Javaid, M.K., Arden, N. (2014). Epidemiology of osteoarthritis. In: Atlas of Osteoarthritis. Springer Healthcare, Tarporley. https://doi.org/10.1007/978-1-910315-16-3_2
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DOI: https://doi.org/10.1007/978-1-910315-16-3_2
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