Epidemiology of osteoarthritis

  • Cyrus CooperEmail author
  • M. Kassim Javaid
  • Nigel Arden


A group of overlapping disorders with different aetiologies but similar biologic, morphologic and clinical outcomes. The disease processes affect articular cartilage, subchondral bone, synovium, capsule and ligaments. Ultimately, cartilage degenerates with fibrillation, fissures, ulceration and full thickness loss of joint surface.Nigel ArdenThis definition is itself developed from one coined by the Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association for the development of criteria for classifying and reporting osteoarthritis in 1986 [1]. It also made the distinction between subclinical, non-symptomatic defects in articular cartilage, which is poorly innervated, and the clinical syndrome, which includes pain, that may develop from such defects [1].


Knee Osteoarthritis Total Knee Replacement Joint Space Narrowing Hand Osteoarthritis Osteoarthritis Progression 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Healthcare 2014

Authors and Affiliations

  1. 1.University of Southampton SH General HospitalSouthamptonUnited Kingdom
  2. 2.University of Oxford the Botnar Research CentreOxfordUnited Kingdom
  3. 3.NDORMSUniversity of OxfordOxfordUnited Kingdom

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