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Clinical Consequences of the Role of Glutamate and Neuroplasticity in Depressive Disorder

  • Philip Gorwood
Chapter

Abstract

Convergent and compelling data exist showing that glutamatergic modulation forms the basis of the effect of antidepressants in major depressive disorder, through its impact on neuroplasticity. However, a significant part of available information is based on animal studies, preclinical works and clinical research, and therefore this hypothesis has to be challenged at a broader clinical level.

Keywords

QBUJFOUT XJUI BTTPDJBUFE XJUI IBWF CFFO DPOUSPMMFE USJBM DPNQBSFE XJUI 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer Healthcare, a part of Springer Science+Business Media 2011

Authors and Affiliations

  • Philip Gorwood

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