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Cellular Plasticity and the Pathophysiology of Depression

  • Thérèse M. Jay
Chapter

Abstract

The precise etiology of depression and other mood disorders remains unknown, and causation is likely to be a multifactorial, involving psychological, genetic, social, and biochemical aspects. However, it is becoming increasingly apparent that neuroplastic changes are implicated in the neurobiological mechanisms that underlie depression. Advances in neuroimaging have allowed investigations into the gross anatomical changes in the brain of people with depression; in parallel with this, post-mortem studies of depressed patients and animal studies using models of depression have explored the molecular, chemical, and cellular phenomena that accompany these gross morphological changes.

Keywords

QBUJFOUT XJUI IBWF CFFO Fluoxetine Patient USFBUNFOU XJUI NFUB BOBMZTJT 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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  • Thérèse M. Jay

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