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This chapter reviews the key elements in the pathophysiology and natural history of atherosclerosis. The interaction between the coagulation cascade and platelet physiology will also be discussed. Our understanding of the complex pathophysiology of atherosclerosis, the coagulation cascade, and platelet physiology is important in order to optimize pharmaceutical and device therapy.
KeywordsAcute Coronary Syndrome Plaque Rupture Coagulation Cascade Necrotic Core Vulnerable Plaque
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