Skip to main content

Costs Associated with Febrile Neutropenia

  • Chapter
  • First Online:
  • 1344 Accesses

Abstract

Evaluation of costs associated with a medical condition and cost effectiveness of therapy do not usually take into account the indirect harm that the condition causes in terms of deterioration of the quality of life. Febrile neutropenia (FN) is an illness requiring antimicrobial therapy and possible hospitalization, often disturbing the familial and social life; it may lead to reduction, delay, or even discontinuation of effective chemotherapy, causing thus a direct prejudice to the patient’s health.

This is a preview of subscription content, log in via an institution.

Buying options

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD   54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Michels SL, Barron RL, Reynolds MW, Smoyer Tomic K, Yu J, Lyman GH. Costs associated with febrile neutropenia in the US. Pharmacoeconomics. 2012;30:809-823.

    Google Scholar 

  2. Schilling MB, Parks C, Deeter RG. Costs and outcomes associated with hospitalized cancer patients with neutropenic complications: a retrospective study. Exp Ther Med. 2011;2:859-866.

    Google Scholar 

  3. Lyman GH, Kuderer N, Greene J, Balducci L. The economics of febrile neutropenia: implications for the use of colony-stimulating factors. Eur J Cancer. 1998;34;1857-1864.

    Google Scholar 

  4. Hirsch BR, Lyman GH. Pharmacoeconomics of the myeloid growth factors. A critical and systematic review. Pharmacoeconomics. 2012;30:497-511.

    Google Scholar 

  5. Lingaratnam S, Worth LJ, Slavin MA, et al. A cost analysis of febrile neutropenia management in Australia: ambulatory v. in-hospital treatment. Aust Health Rev. 2011;35:491-500.

    Google Scholar 

  6. Aapro MS, Bohlius J, Cameron DA, et al; European Organisation for Research and Treatment of Cancer. 2010 update of EORTC guidelines for the use of granulocyte-colony stimulating factor to reduce the incidence of chemotherapy-induced febrile neutropenia in adult patients with lymphoproliferative disorders and solid tumours. Eur J Cancer. 2011;47:8-32.

    Google Scholar 

  7. Kuderer NM, Dale DC, Crawford J, Lyman GH. Impact of primary prophylaxis with granulocyte colony-stimulating factor on febrile neutropenia and mortality in adult cancer patients receiving chemotherapy: a systematic review. J Clin Oncol. 2007;25:3158-3167.

    Google Scholar 

  8. Papaldo P, Lopez M, Marolla P, et al. Impact of five prophylactic filgrastim schedules on hematologic toxicity in early breast cancer patients treated with epirubin and cyclophosphamide. J Clin Oncol. 2005;23:6908-6918.

    Google Scholar 

  9. Klastersky J, Awada A, Aoun M, Paesmans M. Should the indications for the use of myeloid growth factors for the prevention of febrile neutropenia in cancer patients be extended? Curr Opin Oncol. 2009;21:297-302.

    Google Scholar 

  10. Klastersky J, Georgala A, Ameye L, et al. Febrile neutropenia occurring in patients with solid tumors: is the risk of complications affected by the type of chemotherapy? Support Care Cancer. 2010;18(Suppl 3):S101-S102.

    Google Scholar 

  11. Hadji P, Kostev K, Schröder-Bernhardi D, Ziller V. Cost comparison of outpatient treatment with granulocyte colony-stimulating factors (G-CSF) in Germany. Int J Clin Pharmacol Ther. 2012;50:281-289.

    Google Scholar 

  12. Klastersky JA, Paesmans M. Treatment of febrile neutropenia is expensive: prevention is the answer. Onkologie. 2011;34:226-228.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jean A. Klastersky .

Rights and permissions

Reprints and permissions

Copyright information

© 2014 Springer Healthcare

About this chapter

Cite this chapter

Klastersky, J.A. (2014). Costs Associated with Febrile Neutropenia. In: Febrile Neutropenia. Springer Healthcare, Tarporley. https://doi.org/10.1007/978-1-907673-70-2_7

Download citation

  • DOI: https://doi.org/10.1007/978-1-907673-70-2_7

  • Published:

  • Publisher Name: Springer Healthcare, Tarporley

  • Print ISBN: 978-1-907673-69-6

  • Online ISBN: 978-1-907673-70-2

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics