Abstract
The pathogenesis of renal anemia is multifactorial, with a number of contributory processes involved, to a greater or lesser extent.
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Caro J, Brown S, Miller O, et al. Erythropoietin levels in uremic nephric and anephric patients. J Lab Clin Med. 1979;93:449-458.
Fisher JW. Erythropoietin: physiology and pharmacology update. Exp Biol Med. 2003;228:1-14.
Lai PH, Everett R, Wang FF, et al. Structural characterization of human erythropoietin. J Biol Chem. 1986;261:3116-3121.
Browne JK, Cohen AM, Egrie JC. Erythropoietin: gene cloning protein structure and biological properties. Cold Spring Harbor Symp Quant Biol. 1986;51:693-702.
Bernhardt WM, Wiesener MS, Scigalla P, et al. Inhibition of prolyl hydroxylases increases erythropoietin production in ESRD. J Am Soc Nephrol. 2010;21:2151-2156.
Allen DA, Breen C, Yaqoob MM, Macdougall IC. Inhibition of CFU-E colony formation in uremic patients with inflammatory disease: role of IFN-γ and TNF-α. J Investig Med. 1999;47:204-211.
Macdougall IC. Role of uremic toxins in exacerbating anemia in renal failure. Kidney Int Suppl. 2001;78: S67-S72.
Ifudu O, Feldman J, Friedman EA. The intensity of hemodialysis and the response to erythropoietin in patients with end-stage renal disease. N Engl J Med. 1996;334:420-425.
Nemeth E, Rivera S, Gabayan V, et al. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest. 2004;113:1271-1276.
Babitt JL, Lin HY. Molecular mechanisms of hepcidin regulation: implications for the anemia of CKD. Am J Kidney Dis. 2010;55:726-741.
Macdougall IC, Malyszko J, Hider RC, Bansal SS. Current status of the measurement of blood hepcidin levels in chronic kidney disease. Clin J Am Soc Nephrol. 2010;5:1681-1689.
Macdougall IC. Iron supplementation in nephrology and oncology: what do we have in common? Oncologist. 2011;16(suppl 3):25-34.
Eschbach JW, Cook JD, Scribner BH, Finch CA. Iron balance in hemodialysis patients. Ann Intern Med. 1977;87:710-713.
Urena P, Eckardt KU, Sarfati E, et al. Serum erythropoietin and erythropoiesis in primary and secondary hyperparathyroidism: effect of parathyroidectomy. Nephron. 1991;59:384-393.
McCarthy JT, Milliner DS, Johnson WJ. Clinical experience with desferrioxamine in dialysis patients with aluminium toxicity. Q J Med. 1990;74:257-276.
Wu SG, Jeng FR, Wei SY, et al. Red blood cell osmotic fragility in chronically hemodialyzed patients. Nephron. 1998;78:28-32.
Vos FE, Schollum JB, Coulter CV, Doyle TC, Duffull SB, Walker RJ. Red blood cell survival in long-term dialysis patients. Am J Kidney Dis. 2011;58:591-598.
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Macdougall, I.C. (2013). What is the Cause of Renal Anemia?. In: Pocket Reference to Renal Anemia. Springer Healthcare, Tarporley. https://doi.org/10.1007/978-1-907673-48-1_2
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DOI: https://doi.org/10.1007/978-1-907673-48-1_2
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