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Tracheal Reconstruction with Autologous and Engineered Tissues

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Abstract

Tracheal reconstruction remains one of the greater challenges in thoracic surgery. Primary anastomosis is the gold standard in patients requiring resection of anything except extreme lengths of trachea. End-to-end tracheal anastomosis can be safely accomplished following resection of up to one half of the adult trachea. As a result, this approach is available in the vast majority of cases of benign stenosis and in many cases of tumor invasion. The lack of an ideal substitute to replace the trachea’s mechanical and physiological functions is primarily responsible for the shortcomings of tracheal reconstructive surgery in rare patients requiring lengthier resections. Historically, the only therapeutic options in cases of long stenoses or tumors were resection with T-tube placement, terminal tracheostomy, stenting, or other palliative treatments.

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Grunenwald, E., Moss, E., Liberman, M. (2011). Tracheal Reconstruction with Autologous and Engineered Tissues. In: Ferguson, M. (eds) Difficult Decisions in Thoracic Surgery. Springer, London. https://doi.org/10.1007/978-1-84996-492-0_40

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