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L-Arginine and Ischemia-Reperfusion Injury

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Principles of Pulmonary Protection in Heart Surgery

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Abstract

Despite continuous optimization of lung preservation strategies, the lung remains extremely vulnerable to ischemia-reperfusion (I/R) injury.1 It is generally known that I/R-induced lung injury is characterized by (1) increased microvascular permeability and edema, (2) dysfunction of the pulmonary endothelium, (3) aggregation of neutrophils and platelets, and (4) sometimes hemorrhage.

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Authors and Affiliations

  1. Institute for Biodiagnostics, National Research Council of Canada, Winnipeg, MB, Canada

    Yanmin Yang

  2. Department of Cardiovascular and Thoracic Surgery, Shanghai Children’s Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, China

    Yanmin Yang

Authors
  1. Yanmin Yang
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  2. Jiming Cai
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Correspondence to Yanmin Yang .

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Editors and Affiliations

  1. Federal University of Sao Paulo, Sao Paulo, 04023900, Brazil

    Edmo Atique Gabriel

  2. University of Miami, 1611 N.W. 12th Avenue, Miami, 33136, Florida, USA

    Tomas Salerno

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Yang, Y., Cai, J. (2010). L-Arginine and Ischemia-Reperfusion Injury. In: Gabriel, E., Salerno, T. (eds) Principles of Pulmonary Protection in Heart Surgery. Springer, London. https://doi.org/10.1007/978-1-84996-308-4_11

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  • DOI: https://doi.org/10.1007/978-1-84996-308-4_11

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