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Temperature and Brain Protection in Cardiac Surgery

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Brain Protection in Cardiac Surgery

Abstract

It is well known and has been clearly demonstrated that temperature plays a significant role in cerebral physiology and physiopathology, particularly in the setting of cardiac surgery with cardiopulmonary bypass (CPB). The human central nervous system (CNS) receives about 15% of the resting cardiac output and consumes about 20% of the oxygen required by the body at rest. The brain, which accounts for 2% of the total body weight, has an oxygen consumption of about 3.5 mL−1·100 g−1·min−1. This high metabolic rate mandates a high blood flow; therefore, cerebral blood flow (CBF) (Fig. 13.1) is of paramount importance and is normally under metabolic, neural, myogenic, and chemical control.1

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Acknowledgment

The authors thank Mrs. Catherine Friederich Murray and Mr. Steve Palmer for their help with the preparation of this manuscript.

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Authors and Affiliations

  1. Department of Anesthesia and Pain Management, Toronto General Hospital, UHN, University of Toronto, Toronto, Ontario, Canada

    George Djaiani

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  1. George Djaiani
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  2. Harish Ramakrishna
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  3. Alina M. Grigore
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Correspondence to George Djaiani .

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Editors and Affiliations

  1. Dept. Cardiothoracic Surgeon, Queen Elizabeth Hospital, Birmingham, B15 2TH, United Kingdom

    Robert S. Bonser

  2. Cardiothoracic Surgery, Beaumont Road 208, Birmingham, B30 1NX, United Kingdom

    Domenico Pagano

  3. Klinik für Herz-, Thorax-,, Transplantations- und Gefäßchirurgie, Medizinische Hochschule Hannover (MHH), Carl-Neuberg-Str. 1, Hannover, 30625, Germany

    Axel Haverich

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Djaiani, G., Ramakrishna, H., Grigore, A.M. (2011). Temperature and Brain Protection in Cardiac Surgery. In: Bonser, R., Pagano, D., Haverich, A. (eds) Brain Protection in Cardiac Surgery. Springer, London. https://doi.org/10.1007/978-1-84996-293-3_13

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  • DOI: https://doi.org/10.1007/978-1-84996-293-3_13

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