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Sudden Infant Death Syndrome: Gene-Environment Interactions

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Clinical Approach to Sudden Cardiac Death Syndromes

Abstract

Sequencing of the human genome has resulted in a rapidly expanding understanding of the molecular basis of many human diseases and the incredible complexity of genotype-phenotype relationships.1-5 Some genes are expressed only in healthy individuals or in disease conditions, only at specified ages, or in response to specific perturbations or states (e.g., sleep). Some genes, thus contribute to susceptibility to disease, but other genes and their polymorphisms contribute to protection against illness.

“All illnesses have some hereditary contribution. Genetics loads the gun and environment pulls the trigger”

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  1. Uniformed Services University of the Health Sciences, 4550 North Park Avenue, Suite 405, Chevy Chase, Bethesda, MD, 20815, USA

    Carl E. Hunt

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  1. Masonic Medical Research Laboratory, Bleecker St. 2150, Utica, 13501, U.S.A.

    Ramon Brugada

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Hunt, C.E., Hauck, F.R. (2010). Sudden Infant Death Syndrome: Gene-Environment Interactions. In: Brugada, R. (eds) Clinical Approach to Sudden Cardiac Death Syndromes. Springer, London. https://doi.org/10.1007/978-1-84882-927-5_2

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