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Catecholaminergic Polymorphic Ventricular Tachycardia

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Clinical Approach to Sudden Cardiac Death Syndromes

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Abstract

Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited arrhythmia syndrome characterized by adrenergically provoked polymorphic ventricular arrhythmias in the structurally normal heart. This disorder was first described in 1975,1 and its symptoms are usually syncopal episodes triggered by exercise or emotional stress resembling those observed in LQT syndrome.2 The etiological background for the disorder has been described to be the uncontrolled Ca2+ release from the sarcoplasmic reticulum in cardiomyocytes during electrical diastole.3 This abnormality of the Ca2+ function produces delayed afterdepolarizations and thereafter cardiac arrhythmias.4

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Authors and Affiliations

  1. Department of Medicine, Institute of Clinical Medicine, University of Oulu, 5000, 90014, Oulu, Finland

    M. Juhani Junttila

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  1. M. Juhani Junttila
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  2. Olli Anttonen
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  3. Heikki V. Huikuri
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Corresponding author

Correspondence to M. Juhani Junttila .

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Editors and Affiliations

  1. Masonic Medical Research Laboratory, Bleecker St. 2150, Utica, 13501, U.S.A.

    Ramon Brugada

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Junttila, M.J., Anttonen, O., Huikuri, H.V. (2010). Catecholaminergic Polymorphic Ventricular Tachycardia. In: Brugada, R. (eds) Clinical Approach to Sudden Cardiac Death Syndromes. Springer, London. https://doi.org/10.1007/978-1-84882-927-5_12

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  • DOI: https://doi.org/10.1007/978-1-84882-927-5_12

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84882-926-8

  • Online ISBN: 978-1-84882-927-5

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