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Osteogenesis Imperfecta

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Bone and Development

Part of the book series: Topics in Bone Biology ((TBB,volume 6))

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Abstract

Osteogenesis imperfecta (OI) is a group of rare heritable disorders characterized by varying degrees of low bone mass and bone fragility. Overall, OI has an estimated prevalence of between 1 in 10,000 and 1 in 20,000 [4, 59]. A Danish study of a geographically defined population found the point prevalence at birth to be 21.8 in 100,000. Mild forms of OI, however, may not be evident at birth and can be easily overlooked in older children.

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  1. Academic Unity of Child Health, Sheffield Children’s Trust, University of Sheffield, Sheffield, UK

    Paul Arundel & Nicolas J. Bishop

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  1. Paul Arundel
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  1. Health Center, University of Connecticut, Farmington Ave. 263, Farmington, 06030-6125, USA

    Felix Bronner

  2. Dept. Biological Sciences, University of Delaware, Newark, 19716, USA

    Mary C. Farach-Carson

  3. IDS Building, MP887, Bone & Joint Research Group, Tremona Road, Southampton, SO16 6YD, United Kingdom

    H.I (Trudy) Roach

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Arundel, P., Bishop, N.J. (2010). Osteogenesis Imperfecta. In: Bronner, F., Farach-Carson, M., Roach, H. (eds) Bone and Development. Topics in Bone Biology, vol 6. Springer, London. https://doi.org/10.1007/978-1-84882-822-3_13

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