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Biomechanics and Biomaterials in Orthopedics pp 115–122Cite as

Bioreactors for Bone Tissue Engineering

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Abstract

Large bone defect, which often results from the nonunion of the fracture, tumor resection, traumatology and revision reconstruction, is still a great challenge in the orthopaedic surgery. The ideal graft is autogenous bone which is limited in quantity and the harvest procedure is usually painful. The allogenous bone could be used as an alternative. However, the integration and replacement process are slow. And the potential viral and bacterial transmission and the immunoreactions draw back its application. In recent years, more and more biocompatible and biodegradable materials are used as bone substitutes. And tissue engineering provides a tool to create a living bone in vitro.

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Author information

Authors and Affiliations

  1. Department of Orthopaedic Surgery, Ninth People’s Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China

    Youzhuan Xie MD, PhD & Jianxi Lu MD, PhD

Authors
  1. Youzhuan Xie MD, PhD
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  2. Jianxi Lu MD, PhD
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Correspondence to Youzhuan Xie MD, PhD .

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Editors and Affiliations

  1. Hôpital Nord, Aix-Marseille Université, Marseille CX 20, France

    Dominique G. Poitout

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© 2016 Springer-Verlag London

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Xie, Y., Lu, J. (2016). Bioreactors for Bone Tissue Engineering. In: Poitout, D. (eds) Biomechanics and Biomaterials in Orthopedics. Springer, London. https://doi.org/10.1007/978-1-84882-664-9_9

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  • DOI: https://doi.org/10.1007/978-1-84882-664-9_9

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  • Print ISBN: 978-1-84882-663-2

  • Online ISBN: 978-1-84882-664-9

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