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Hereditary and Developmental Neuromuscular Disorders

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Children's Orthopaedics and Fractures

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Abstract

This chapter considers those conditions characterized by weakness resulting from pathology primarily in the muscles or the anterior horn cells of the spinal cord. In their later stages these disorders have recognizable clinical features, but in the early stages all share a common set of symptoms and physical signs. Generally, motor disorders are either genetic or acquired. Children with the former tend to present with weakness and delayed motor skills whereas those with the acquired type usually have fairly rapid progression of weakness and loss of function. Children who are floppy at birth are likely to be evaluated initially by a paediatrician or paediatric neurologist but the orthopaedic surgeon may be the first specialist to assess a child with a walking difficulty caused by Duchenne’s or Becker’s dystrophy.

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Acknowledgments

We thank Dr Paul Eunson, consultant paediatric neurologist, Royal Hospital for Sick Children Edinburgh, for his helpful suggestions in the preparation of this chapter and for providing many of the clinical illustrations, and Dr Colin Smith, senior lecturer in pathology, University of Edinburgh, for providing the histological illustrations.

Author information

Authors and Affiliations

  1. Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA, USA

    Eugene E. Bleck

  2. Department of Orthopaedic Surgery, Edinburgh, UK

    James E. Robb

  3. Royal Hospital for Sick Children, Edinburgh, UK

    James E. Robb

  4. University of Edinburgh, Edinburgh, UK

    James E. Robb

  5. University of St. Andrews, Edinburgh, UK

    James E. Robb

Authors
  1. Eugene E. Bleck
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  2. James E. Robb
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Editor information

Editors and Affiliations

  1. Nuffield Orthopaedic Centre, University of Oxford, Windmill Road, Oxford, OX3 7LD, United Kingdom

    Michael Benson

  2. Sick Children, Great Ormond Street Hospital for, Greater Ormond Street, London, WC1N 3JH, United Kingdom

    John Fixsen

  3. Orthopaedic Hospital, Princess Margaret Rose, Frogston Road West 41-43, Edinburgh, EH10 7ED, United Kingdom

    Malcolm Macnicol

  4. Orthopädie, Olgahospital, Bismarckstr. 8, Stuttgart, 70176, Germany

    Klausdieter Parsch

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© 2010 Springer-Verlag London Limited

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Bleck, E.E., Robb, J.E. (2010). Hereditary and Developmental Neuromuscular Disorders. In: Benson, M., Fixsen, J., Macnicol, M., Parsch, K. (eds) Children's Orthopaedics and Fractures. Springer, London. https://doi.org/10.1007/978-1-84882-611-3_16

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  • DOI: https://doi.org/10.1007/978-1-84882-611-3_16

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84882-610-6

  • Online ISBN: 978-1-84882-611-3

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