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Physiology and Wound Healing

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Book cover Plastic and Reconstructive Surgery

Part of the book series: Springer Specialist Surgery Series ((SPECIALIST))

Summary

Wound Healing is a complex and tightly regulated process involving different cell types and a large number of growth factors and cytokines which have their specific roles in the wound healing phases which are referred to as inflam-mation, proliferation and regeneration. Dysre-gu lation of the physiologic wound healing process may lead to disturbed wound healing such as scar formation or delayed healing. The aim of current wound therapy is to optimize conditions for the healing process and provide custom-tailored individual treatment for different wound healing problems by the use of adjunct therapies as well as innovative therapeutic strategies.

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Abbreviations

bFGF:

Basic fibroblast growth factor

GM-CSF:

Granulocyte monocyte colony stimulating factor

IFNγ:

Interferon-gamma

IL:

Interleukin

MMP:

Matrix metalloproteinase

PDGF:

Platelet-derived growth factor

PF:

Platelet factor

TGF:

Transforming growth factor

TNF:

Tumor necrosis factor

tPA:

Tissue-type plasminogen activator

uPA:

Urokinase-type plasminogen activator

VEGF:

Vascular endothelial growth factor

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Author information

Authors and Affiliations

  1. Department of Plastic and Hand Surgery, Erlangen University Hospital, Erlangen, Germany

    Raymund E. Horch, Oliver Bleiziffer & Ulrich Kneser

Authors
  1. Raymund E. Horch
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  2. Oliver Bleiziffer
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  3. Ulrich Kneser
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Editor information

Editors and Affiliations

  1. Department of Plastic Surgery, Cleveland Clinic, Cleveland, OH, USA

    Maria Z. Siemionow (Professor of Surgery, Director of Plastic Surgery Research, Head of Microsurgery Training) (Professor of Surgery, Director of Plastic Surgery Research, Head of Microsurgery Training)

  2. Department of Plastic and Aesthetic, Hand, and Reconstructive Surgery, Caritas-Krankenhaus St. Josef, affiliated with Regensburg University, Regensburg, Germany

    Marita Eisenmann-Klein (Director) (Director)

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© 2010 Springer-Verlag London Limited

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Horch, R.E., Bleiziffer, O., Kneser, U. (2010). Physiology and Wound Healing. In: Siemionow, M.Z., Eisenmann-Klein, M. (eds) Plastic and Reconstructive Surgery. Springer Specialist Surgery Series. Springer, London. https://doi.org/10.1007/978-1-84882-513-0_1

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  • DOI: https://doi.org/10.1007/978-1-84882-513-0_1

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84882-512-3

  • Online ISBN: 978-1-84882-513-0

  • eBook Packages: MedicineMedicine (R0)

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