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Hypoplastic Left Heart Syndrome

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Critical Care of Children with Heart Disease

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Abstract

Hypoplastic left heart syndrome (HLHS) is the most common severe congenital heart defect which constitutes 1–2% of all congenital heart anomalies and 7–9% of total anatomic abnormalities diagnosed within the 1 year of life. It is also the most common congenital cardiac malformation involving a single ventricle. It is more frequent in males, with a 67% male predominance. Without surgical intervention HLHS is a uniformly fatal condition with a 95% mortality rate within the 1 month of life. A multifactorial mode of inheritance is likely present for most cases [1].

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Authors and Affiliations

  1. Pediatric Cardiovascular Intensive Care Unit, Sanger Clinic, Levine Children’s Hospital, Charlotte, NC, USA

    Yuliya A. Domnina

Authors
  1. Yuliya A. Domnina
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  2. Ricardo Muñoz
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  3. Traci M. Kazmerski
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  4. Jackie Kreutzer
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  5. Victor O. Morell
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Corresponding author

Correspondence to Yuliya A. Domnina .

Editor information

Editors and Affiliations

  1. Children's Hospital, Pittsburgh, 5th Ave. 3705, Pittsburgh, 15213, USA

    Ricardo Munoz

  2. School of Medicine, Children's Hospital, University of Pittsburgh, Fifth Ave. 3705, Pittsburgh, 15213, USA

    Victor Morell

  3. Chemin de Normanie 2, Geneve, 1206, Switzerland

    Eduardo Cruz

  4. Children's Hospital, Pittsburgh, 5th Ave. 3705, Pittsburgh, 15213, USA

    Carol Vetterly

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© 2009 Springer-Verlag London Limited

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Domnina, Y.A., Muñoz, R., Kazmerski, T.M., Kreutzer, J., Morell, V.O. (2009). Hypoplastic Left Heart Syndrome. In: Munoz, R., Morell, V., Cruz, E., Vetterly, C. (eds) Critical Care of Children with Heart Disease. Springer, London. https://doi.org/10.1007/978-1-84882-262-7_30

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  • DOI: https://doi.org/10.1007/978-1-84882-262-7_30

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84882-261-0

  • Online ISBN: 978-1-84882-262-7

  • eBook Packages: MedicineMedicine (R0)

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