Skip to main content

Clinical Aspects of Nerve Injury

  • Chapter
  • First Online:
Surgical Disorders of the Peripheral Nerves

Abstract

In the acute injury the object of the clinician must be to recognise the fact of injury as soon as possible after the event, and later to go on to determine the nerve or nerves affected, the level or levels of injury and the extent and depth of the lesion or lesions. That this is not always easy nor always appreciated is apparent to anyone who has been able to study the records of the medical defense organisations. The history is important: high velocity injury, compound fracture and wounding, accidental, criminal, surgical or all three, are likely to mean that there has been a serious lesion. The use of a knife, often enough in the hand of a surgeon, is an indication that a nerve is likely to have been partly or completely severed. Advice from witnesses or emergency paramedical staff is always valuable. Potentially life or limb threatening injuries complicate closed traction lesion of the supraclavicular brachial plexus in at least 20% of cases. Even more patients with injuries to the lumbo-sacral plexus are so threatened. The subclavian artery is ruptured in 10% of complete lesions of the brachial plexus and in as many as 30% of cases of violent traction injury of the infraclavicular portion of the brachial plexus. The incidence of arterial lesion is high after fracture dislocations of the shoulder and elbow, higher still after fracture dislocations of the knee. It is important always to search with diligence for occult injuries to the head, the spine, the chest, the abdomen and pelvis before embarking upon treatment of the nerve lesion, both at the first hospital but also after transfer to another Unit (Fig. 5.1).

Rolfe Birch M. Chir, FRCP&S (Glas), FRCS (Edin), FRCS (Eng) by election Professor in Neurological Orthopaedic Surgery, University College, London

Visiting Professor, Department of Academic Neurology, Imperial College, London

Honorary Orthopaedic Consultant, Hospital for Sick Children Great Ormond Street, London

The National Hospital for Nervous Diseases, Queen Square, London

Raigmore Hospital, Inverness

Honorary Orthopaedic Surgeon to the Royal Navy

Consultant in Charge, War Nerve Injuries Clinic at the Defence Medical Rehabilitation Centre, Headley Court, Leatherhead, Surrey

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  • Anand P, Birch R (2002) Restoration of sensory function and lack of long-term chronic pain syndromes after brachial plexus injury in human neonates. Brain 125:113–122

    Article  PubMed  CAS  Google Scholar 

  • Anand P, Warner G, Parrett A, Terenghi G, Kopelman P, Ghatei MA, Bloom SR, Sinicropi D, Williams-Chestnut RE (1994) Nerve growth factor related small fibre dysfunction in human diabetic neuropathy. Ann Neurol 36:284A

    Google Scholar 

  • Anand P, Terenghi G, Warner G, Kopelman P, Sinicropi DV, Williams-Chestnut RE (1996) The role of nerve growth factor in human diabetic neuropathy. Nat Med 2:703–707

    Article  PubMed  CAS  Google Scholar 

  • Atherton DD, Facer P, Roberts KM, Misra VP, Chizh BA, Bountra C, Anand P (2007) Use of the novel contact heat evoked potential stimulator (CHEPS) for the assessment of small fibre neuropathy: correlations with skin flare responses and intra-epidermal nerve fibre counts. BMC Neurol 7:21

    Article  PubMed  Google Scholar 

  • Backman C, Nystrőm A, Balkman A, Bjerle P (1993) Arterial spasticity and cold intolerance after digital replantation. J Hand Surg Br 18:551–555

    PubMed  CAS  Google Scholar 

  • Bell J, Burford W (1982) The force time relationship of clinically used sensory testing instruments. Presented at the American Society for Surgery of the Hand, 37th Annual Meeting, New Orleans

    Google Scholar 

  • Birch R (1986) Lesions of peripheral nerves: the present situation. J Bone Joint Surg Br 68:2–8

    PubMed  CAS  Google Scholar 

  • Birch R (1989) The repair of peripheral nerves: experimental and clinical observations. Thesis for the degree of Master of Surgery, University of Cambridge

    Google Scholar 

  • Birch R, Raji ARM (1991) Repair of median and ulnar nerves. J Bone Joint Surg Br 73:154–157

    PubMed  CAS  Google Scholar 

  • Bonney G (1983) Peripheral nerve lesions. In: Harris NH (ed) Clinical orthopaedics, Wright, Bristol, pp 726

    Google Scholar 

  • Bowden REM, Scholl DA (1954) Rates of regeneration. In: Seddon HJ (ed) Peripheral nerve injuries, vol 282, Medical Research Council Special Report Series. HMSO, London, pp 16–24

    Google Scholar 

  • Brand PW (1985) Clinical mechanics of the hand. Mosby, St. Louis, pp 61–191

    Google Scholar 

  • Buck-Gramcko D, Lubahn JD (1993) The Hoffman-Tinel sign. J Hand Surg Br 18:800–805

    Article  PubMed  Google Scholar 

  • Camp SJ (2010) Lesions of the spinal accessory nerve. J Bone Joint Surg (in print)

    Google Scholar 

  • Canale ST, Beaty JH, Warner WC, Sharp RS (2000) Passive flexion sign: a simple tool for diagnosis of anterior interosseous nerve injury in children. J Bone Joint Surg 82:1354–1355

    PubMed  CAS  Google Scholar 

  • Cartwright MS, Chloros GD, Walker FO, Wiesler ER, Campbell WW (2007) Diagnostic ultrasound for nerve transection. Muscle Nerve 35(6):796–799

    Article  PubMed  Google Scholar 

  • Chan V (2003) Applying ultrasound imaging to Interscalene brachial plexus block. Reg Anesth Pain Med 28:340–343

    PubMed  Google Scholar 

  • Cokluk C, Aydin K (2007a) Ultrasound examination in the surgical treatment for upper extremity peripheral nerve injuries: part I. Turk Neurosurg 17(4):277–282

    PubMed  Google Scholar 

  • Cokluk C, Aydin K (2007b) Ultrasound examination in the surgical treatment for upper extremity peripheral nerve injuries: part II. Turk Neurosurg 17(3):197–201

    PubMed  Google Scholar 

  • Coupland RM (1993) War wounds of limbs. Butterworth Heinemann, Oxford, London

    Google Scholar 

  • Davis KD, Pope GE (2002) Noxious cold evokes multiple sensations with distinct time cause. Pain 98:179–185

    Article  PubMed  Google Scholar 

  • Dellon AL (1978) The moving two-point discrimination test: clinical evaluation of the quickly-adapting fibre receptor system. J Hand Surg 3:474–481

    CAS  Google Scholar 

  • Dunnet W, Housden P, Birch R (1995) Results of flexor to extensor tendon transfer. J Hand Surg Br 20(1):26–28

    Article  PubMed  CAS  Google Scholar 

  • Dyck PJ, O’Brien PC, Johnson DM, Klein CJ, Dyck PJB (2005) Quantitative sensory testing. In: Dyck PJ, Thomas PK (eds) Peripheral neuropathy, 4th edn. Elsevier, Philadelphia

    Google Scholar 

  • Gilliatt RW, Taylor JC (1959) Electrical changes following section of the facial nerve. Proc R Soc Med 52:1080–1083

    PubMed  CAS  Google Scholar 

  • Head H, Rivers WHR, Sherren J (1905) The afferent nervous system from a new aspect. Brain 28:99–116

    Article  Google Scholar 

  • Henderson WR (1948) Clinical assessment of peripheral nerve injuries. Tinel’s test. Lancet 2:801–806

    Article  PubMed  CAS  Google Scholar 

  • Highet WB (1941) Memorandum to the nerve injuries committee of the Medical Research Council and published in the Special Report Series No. 282 1954. HMSO, London

    Google Scholar 

  • Highet WB (1954) Quoted by Zachary RB. In: Seddon HJ (ed) Peripheral nerve injuries Medical Research Council Special Report Series No 282. HMSO, London, p 355

    Google Scholar 

  • Hoffman P (1915a) Über eine Methode, den Erfolg einer Nervennant zu beurteilen. Med Klin 11:359–360

    Google Scholar 

  • Hoffman P (1915b) Weiterres über das Verhalten frisch regenerierter Nerven über die Methode, den Erfolg einer Nervennaht Frühzeitig zu beurteilen. Med Klin 11:856–858

    Google Scholar 

  • Htut M, Misra P, Anand P, Birch R, Carlstedt T (2006) Pain phenomena and sensory recovery following brachial plexus avulsion injury and surgical repair. J Hand Surg Br 31:596–605

    Article  PubMed  CAS  Google Scholar 

  • Htut M, Misra VP, Anand P, Brich R, Carlstedt T (2007) Motor recovery and the breathing arm after brachial plexus surgical repair including re-implantation of avulsed spinal nerves into the spinal cord. J Hand Surg 32E:170–178

    Google Scholar 

  • Inman VT, Saunders JB, Abbott LC (1944) Observation on the function of the shoulder joint. J Bone Joint Surg 26:1–31

    Google Scholar 

  • Irwin MS, Gilbert SEA, Terenghi G, Smith RW, Green CJ (1997) Cold intolerance following peripheral nerve injury. Br J Hand Surg 22:308–316

    Article  CAS  Google Scholar 

  • Jerosch-Herold C (2000) Should sensory function after median nerve injury and repair be quantified using two point discrimination as a critical measure? J Plast Reconstr Surg 34:339–343

    Article  CAS  Google Scholar 

  • Jerosch-Herold C (2005) Assessment of sensibility after nerve injury and repair: a systematic review of evidence for validity, reliability and responsiveness of tests. J Hand Surg Br 30:252–264

    Article  PubMed  CAS  Google Scholar 

  • Kato N, Birch R (2006) Peripheral nerve palsies associated with closed fractures and dislocations. Injury 37:507–512

    Article  PubMed  Google Scholar 

  • Kaufmann KR (2005) Quantitative muscle strength assessment. In: Dyck PJ, Thomas PK (eds) Peripheral neuropathy, 4th edn. Elsevier, Philadelphia, pp 1095–1102

    Chapter  Google Scholar 

  • Kay S (1985) Venous occlusion plethysmography in patients with cold related symptoms after digital salvage procedures. J Hand Surg Br 10:151–154

    Article  PubMed  CAS  Google Scholar 

  • Keogh Sir Alred (1917) Introduction to: notes on military orthopaedics (Author. Robert Jones), Cassell, London

    Google Scholar 

  • Krone S (2005) Ultrasound guided regional anaesthesia. Invited paper to advanced orthopaedic anaesthesia and critical care. Royal National Orthopaedic Hospital, Stanmore, Middlesex, 16 September 2005

    Google Scholar 

  • Landau WM (1953) The duration of neuromuscular function after nerve section. Neurosurgery 10:64–68

    Article  CAS  Google Scholar 

  • Landi A, Copeland S (1979) Value of the tinel sign in brachial plexus lesions. Ann R Coll Surg Engl 61:470–471

    PubMed  CAS  Google Scholar 

  • Lewis T, Pickering GW (1936) Circulatory changes in the fingers in some diseases of the nervous system, with special reference to the digital atrophy of peripheral nerve lesions. Clin Sci 2:149–183

    Google Scholar 

  • Lithell M, Backman C, Nystrőm Å (1997) Pattern recognition in post-traumatic cold intolerance. J Hand Surg 22:783–787

    CAS  Google Scholar 

  • MacKinnon SE, Dellon AL (1985) Two point discrimination tester. J Hand Surg Am 10:906–907

    PubMed  CAS  Google Scholar 

  • MacKinnon SE, Dellon AL (1988) Ischaemia of nerve: loss of vibration sensibility. In: Surgery of the peripheral nerve. Thieme Medical Publishers/Georg Thieme Verlag, Stuttgart, New York, p 57

    Google Scholar 

  • Malenfant A, Forget R, Amsel R, Papillon J, Frigon J-Y, Choinière M (1998) Tactile thermal and pain sensibility in burned patients with and without chronic pain and paraesthesia problems. Pain 77:241–251

    Article  PubMed  CAS  Google Scholar 

  • Martinoli C, Serafini G, Bianchi S, Bertoletto M, Gandolfo N, Derchi LE (1996) Ultrasonography of peripheral nerves. J Peripher Nerv Syst 1:169–178

    PubMed  CAS  Google Scholar 

  • Merrington WR, Nathan PW (1949) A study of post-ischaemic paraesthesiae. J Neurol Neurosurg Psychiatry 12:1–18

    Article  PubMed  CAS  Google Scholar 

  • Mills K (1997) Wasting, weakness and the MRC scale in the first dorsal interosseous muscle. J Neurol Neurosurg Psychiatry 62:541–542

    Article  PubMed  CAS  Google Scholar 

  • Moberg E (1958) Objective methods for determining the functional value of sensibility in the hand. J Bone Joint Surg Br 40:454–476

    PubMed  Google Scholar 

  • Narakas AO (1993) Paralytic disorders of the shoulder girdle. In: Tubiana R (ed) The hand, vol. 4. Saunders, Philadelphia, pp 112–125, Chapter 9

    Google Scholar 

  • Novak VP, Baratz ME (2006) Antero-medial ecchymosis about the elbow in an adult with a distal humerus fracture. J Hand Surg Am 31:860–862

    Article  PubMed  Google Scholar 

  • Novak CB, MacKinnon SE (1999) Letter to editor. J Hand Surg Am 24:869–870

    Article  PubMed  CAS  Google Scholar 

  • O’Brian M (ed) (2000) Aids to the examination of the peripheral nervous system, 4th edn. Elsevier, London

    Google Scholar 

  • Oaklander AL, Rismiller JG, Gelman LB, Zheng L, Chang Y, Gott R (2006) Evidence of focal small-fibre axonal degeneration in complex regional pain syndrome-1 (reflex sympathetic dystrophy). Pain 120:235–243

    Article  PubMed  Google Scholar 

  • Perlas A, Chan V, Simons M (2003) Brachial plexus examination and localization using ultrasound and electrical stimulation. Anaesthesiology 99:429–435

    Article  Google Scholar 

  • Perry J, Ireland ML, Gronley J, Hoffer MM (1986) Predictive value of manual muscle testing and gait analysis in normal ankles by dynamic electromyography. Foot Ankle Int 6:254

    CAS  Google Scholar 

  • Porter RW (1966) New test for finger sensation. BMJ 2:927

    Article  PubMed  CAS  Google Scholar 

  • Rank BK, Wakefield AR, Hueston JT (1973) Surgery of repair as applied to hand injuries, 4th edn. Churchill Livingstone, Edinburgh

    Google Scholar 

  • Riddoch G (1940) The coin test. In: Surgical disorders of the peripheral nerves (Attributed: Seddon HJ 1975), Churchill Livingstone, Edinburgh, p 53

    Google Scholar 

  • Rosén B, Jerosch-Herold C (2000) Comparing the responsiveness over time of two tactile gnosis test: two-point discrimination and the STI test. J Hand Surg 5:114–119

    Google Scholar 

  • Rowntree T (1949) Anomalous innervation of the hand muscles. J Bone Joint Surg Br 31:505–510

    Google Scholar 

  • Seddon HJ (1975) Surgical disorders of the peripheral nerves, 2nd edn. Churchill Livingstone, Edinburgh, London, New York, p 177

    Google Scholar 

  • Seddon HJ (ed) (1954) Peripheral nerve injuries. Medical Research Council Special Report Series No 282. HMSO, London

    Google Scholar 

  • Sharrard WJW (1953) Correlations between the changes in the spinal cord and muscular paralysis in poliomyelitis. Proc R Soc Lon 40:346

    Google Scholar 

  • Smith SJM (1996) The role of neurophysiological investigation in traumatic brachial plexus injuries in adults and children. J Hand Surg Br 21:145–148

    Article  PubMed  CAS  Google Scholar 

  • Smith SJM (1998) Electrodiagnosis. In: Birch R, Bonney G, Wynn Parry C (eds) Surgical disorders of the peripheral nerves, 1st edn. Churchill Livingstone, Edinburgh, London, pp 467–490, Chapter 19

    Google Scholar 

  • Smith SJM (1999) Neurophysiological interpretation after nerve injury in the upper limb. Curr Orthopaed 13:27–32

    Article  Google Scholar 

  • Smith PJ, Mott G (1986) Sensory threshold and conductance testing in nerve injuries. J Hand Surg Br 11:157–162

    Article  PubMed  CAS  Google Scholar 

  • Stewart M, Birch R (2001) Penetrating missile injuries. J Bone Joint Surg Br 83:517–524

    Article  PubMed  CAS  Google Scholar 

  • Szabo RM, Gelberman RH, Williamson RV, Dellon AL, Yavu NC, Dimick NP (1984) Vibratory sensory testing in acute peripheral nerve compression. J Hand Surg Am 9:104–109

    Google Scholar 

  • Tinel J (1915) Le signe du “fourmillement” dans les lésions des nerfs periphériques. Presse Méd 47:388–399

    Google Scholar 

  • Tinel J (1917) Nerve wounds. Ballière Tindall & Cox, London. Authorised translation by Rothwell F, revised and edited by Joll CA

    Google Scholar 

  • Toros J, Karabay N, Őzaksar K, Sugun TS, Kayalar M, Bal E (2009) Evaluation of peripheral nerves of the upper limb of the upper limb with ultrasonography. J Bone Joint Surg Br 91:762–766

    Article  PubMed  CAS  Google Scholar 

  • Trumble TE, Kahn U, Vanderhooft E, Bach AW (1995) A technique to quantitate motor recovery following nerve grafting. J Hand Surg Am 20:367–372

    Article  PubMed  CAS  Google Scholar 

  • von Greulich M (1976) Der zweipunkte-Stern. Handchirurgie 8:97–99

    PubMed  CAS  Google Scholar 

  • Wynn Parry CB (1953) Electrical methods in diagnosis and prognosis of peripheral nerve injuries. Brain 76:229–265

    Article  PubMed  CAS  Google Scholar 

  • Wynn Parry CB, Salter RM (1976) Sensory re-education after median nerve lesions. Br J Hand Surg 8:250–257

    Google Scholar 

  • Wynn Parry CB (1981) Rehabilitation of the hand, 4th edn. Butterworth, London

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2010 Springer London

About this chapter

Cite this chapter

Birch, R. (2010). Clinical Aspects of Nerve Injury. In: Surgical Disorders of the Peripheral Nerves. Springer, London. https://doi.org/10.1007/978-1-84882-108-8_5

Download citation

  • DOI: https://doi.org/10.1007/978-1-84882-108-8_5

  • Published:

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84882-107-1

  • Online ISBN: 978-1-84882-108-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics