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Metabolic Bone Disorders

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Abstract

1.Osteomalacia a. Word means “soft bones” b. Impaired mineralization (deposition of hydroxyapatite) in mature bone c. Pathogenesis i. Inadequate concentration of extracellular fluid phosphate and/or calcium ii. A circulating inhibitor of mineralization d. Major causes i. Vitamin D deficiency 1. Low oral intake plus inadequate sunlight exposure 2. Intestinal malabsorption

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© 2011 Springer-Verlag London Limited

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Colburn, N.T. (2011). Metabolic Bone Disorders. In: Review of Rheumatology. Springer, London. https://doi.org/10.1007/978-1-84882-093-7_24

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  • DOI: https://doi.org/10.1007/978-1-84882-093-7_24

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84882-092-0

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