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Practical Guidelines for the Treatment of Erectile Dysfunction and Peyronie´s Disease

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Practical Urology: Essential Principles and Practice

Part of the book series: Springer Specialist Surgery Series ((SPECIALIST))

Abstract

Erectile dysfunction (ED) is defined as persistent inability to attain and/or maintain an erection sufficient for sexual performance.1,2 It is assumed that 5–20% of men complain of moderate to severe ED3; common risk factors are very similar to risk factors of cardiovascular disease and include smoking, hypertension, diabetes, lipidemia, atherosclerosis, and pelvic surgery.2,4 The introduction of oral drugs has revolutionized the medical treatment of ED; successful intercourse can be achieved with inhibitors of phosphodiesterase 5 (PDE-5) such as sildenafil, tadalafil, and vardenafil in about 75% of patients suffering from ED.5 However, a considerable amount of men does not respond to PDE-5 inhibitors, particularly patients with diabetes mellitus (DM) or patients having undergone radical prostatectomy. This chapter aims to present a pragmatic approach for the clinical diagnosis and therapy of ED, based on available literature, particularly the guidelines of the European Association of Urology,6 the American Urological Association7 as well as the British Society for Sexual Medicine,5 and on current research and clinical practice.

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Author information

Authors and Affiliations

  1. Department of Urology, University-Hospital Grosshadern, Ludwig-Maximilians-University Munich, Munich, Germany

    Christian Gratzke & Christian G. Stief

  2. Institute for Regenerative Medicine, Wake Forest University Medical School, Winston Salem, NC, USA

    Karl-Erik Andersson

  3. Department of Urology, University-Hospital Giessen and Marburg GmbH, Justus-Liebig-University Giessen, Giessen, Germany

    Thorsten Diemer

  4. Department of Urology, Pediatric Urology and Andrology, University Hospital Giessen and Marburg GmbH, Giessen, Germany

    Wolfgang Weidner

Authors
  1. Christian Gratzke
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  2. Karl-Erik Andersson
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  3. Thorsten Diemer
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  4. Wolfgang Weidner
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  5. Christian G. Stief
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Editor information

Editors and Affiliations

  1. Dept. of Urology, J Floor, Royal Hallamshire Hospital, Glossop Road, Sheffield, S10 2JF, United Kingdom

    Christopher R. Chapple

  2. Dept. Urology, University of Virginia Health System, Charlottesville, Virgin Islands, USA

    William D. Steers

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© 2011 Springer London

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Gratzke, C., Andersson, KE., Diemer, T., Weidner, W., Stief, C.G. (2011). Practical Guidelines for the Treatment of Erectile Dysfunction and Peyronie´s Disease. In: Chapple, C., Steers, W. (eds) Practical Urology: Essential Principles and Practice. Springer Specialist Surgery Series. Springer, London. https://doi.org/10.1007/978-1-84882-034-0_28

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  • DOI: https://doi.org/10.1007/978-1-84882-034-0_28

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  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84882-033-3

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