Abstract
Metastatic disease remains a significant source of morbidity for the cancer patient. Approximately 50% of patients diagnosed with cancer will develop metastases, and of these, 70% will develop symptoms [10]. Pain is the most common symptom resulting from bone metastases and is described as severe in more than 50% of hospitalized cancer patients [4].
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References
Baker M. (2005) Stanford News Service, Stanford University, Stanford, CA, May 18th.
Benzil DL, Saboori M, Mogilner AY, Rochio R, Moorthy CR.(2004) Safety and efficacy of stereotactic radiosurgery for tumors of the spine. Journal of Neurosurgery,101:413–418.
Blitzer PH. (1985) Re-analysis of the RTOG study of the palliation of symptomatic osseous metastases. Cancer, 55:1468–1472.
Brescia FJ, Portenoy RK, Ryan M, Krasnoff L, Gray G. (1992) Pain, opoid use, and survival in hospitalized patients with advanced cancer. Journal of Clinical Oncology, 10:149–155.
Bucholz R. (2006) A look into the future: robotic radiosurgery. RT Image, Valley Forge Publishing, 9:40.
Chang E, Shiu A, Lii M, Rhines L, Mendel E, Mahajan A, Weinberg J, Mathews L, Brown B, Maor M, Cox J. (2004) Phase 1 clinical evaluation of near-simultaneous computed tomographic image-guided stereotactic radiotherapy for spinal metastases. International Journal of Radiation Oncology, Biology, and Physics,59(5):1288–1294.
Chang E, Shiu A, Mendel E, Mathews L, Mahajan A, Allen P, Weinberg J, Brown B, Wang X, Woo S, Cleeland C, Maor M, Rhines L. (2007) Phase I/II study of stereotactic body radiotherapy for spinal metastasis and its pattern of failure. Journal of Neurosurgery. Spine, 7: 151–160.
Chow E, Harris K, Fan G, Tsao M, Sze W. (2007) Palliative radiotherapy trials for bone metastases: a systematic review. Journal of Clinical Oncology, 25(11):1423–1436.
Cox J, Ang K. (2003) Radiation Oncology: Rationale, Techniques, Results. 8th Edition, Mosby, St Louis, 3–4.
Cox J, Ang K. (2003) Radiation Oncology: Rationale, Technique, Results. 8th Edition, Mosby, St Louis, 954.
Emami B, Lyman J, Brown A, Coia L, Goiten M, Munzenride JE, Shank B, Solin LJ, Wessom M. (1991) Tolerance of normal tissue to therapeutic radiation. International Journal of Radiation Oncology, Biology, and Physics,21:109–122.
Enck. (2001) The Medical Care of Terminally Ill Patients. Johns Hopkins University Press, Baltimore, MD, 157.
Gerszten P, Burton S, Ozhasoglu C, Welch W. (2007) Radiosurgery for spinal metastases: clinical experience in 500 cases from a single institution. Spine, 32(2): 193–199.
Gerszten P, Welch W. (2003) Cyberknife radiosurgery for the spine. Techniques in Neurosurgery, 9:232–241.
Hall E, Giaccia A. (2006) Radiobiology for the Radiologist. 6th Edition, Lippincott Williams & Wilkins, Philadelphia, PA, 11.
Hall E, Giaccia A. (2006) Radiobiology for the Radiologist. 6th Edition, Philadelphia, Lippincott Williams & Wilkins, Philadelphia, PA, 16.
Hall E, Giaccia A. (2006) Radiobiology for the Radiologist, 6th Edition, Lippincott Williams & Wilkins, Philadelphia, PA, 340.
Hall E, Giaccia A. (2006) Radiobiology for the Radiologist, 6th Edition, Philadelphia, Lippincott Williams & Wilkins, Philadelphia, PA, 342.
Hall E, Giaccia A. (2006) Radiobiology for the Radiologist, 6th Edition, Philadelphia, Lippincott Williams & Wilkins, Philadelphia, PA, 378–381.
Hartsell W, Scott C, Bruner D, Scarantino C, Ivker R, Roach M, Suh J, Demas W, Movsas B, Petersen I, Konski A, Cleeland C, Janjan N, DeSilvio M. (2005) Randomization of short- versus long-course radiotherapy for palliation of painful bony metastases. Journal of the National Cancer Institute, 97:798–804.
Heilbrun P. (2003) Cyberknife Radiosurgery: A Practical Guide, Sunnyvale, The Cyberknife Society, vii.
Khan F. (2003) The Physics of Radiation Therapy, 3rd Edition, Lippincott Williams & Wilkins, Philadelphia , PA, 28.
Khan F. (2003) The Physics of Radiation Therapy, 3rd Edition, Philadelphia, Lippincott Williams & Wilkins, Philadelphia, PA, 106.
Khan F. (2003) The Physics of Radiation Therapy, 3rd Edition, Philadelphia, Lippincott Williams & Wilkins, Philadelphia, PA, 508.
Khan F. (2003) The Physics of Radiation Therapy, 3rd Edition, Philadelphia, Lippincott Williams & Wilkins, Philadelphia, PA, 514–515.
Linear Accelerator from World of Invention. (2006) Thompson Gale, 1–3.
Lu C, Stomper P, Drislane F, Wen P, Block C, Humphrey C, Collins C, Jolesz F, Talcott J. (1998) Suspected spinal cord compression in breast cancer patients: a multidisciplinary risk assessment. Breast Cancer Research and. Treatment, 51:121–131.
Medical News Today (2007)CyberKnife Spinal Tumor Treatments Increase By 56 Percent - Success Of Non-Invasive Procedure Chronicled In The Journal Spine.February 23rd.
Mell L, Kochanski J, Roeske J, Haslam J, Mehta N, Yamada D, Hurtheau J, Collins Y, Lengyel E, Mundt A. (2006) Dosimetric predictors of acute hematologic toxicity in cervical cancer patients treated with concurrent cisplatin and intensity-modulated pelvic radiotherapy. International Journal of Radiation Oncology, Biology, and Physics,66(5):1356–1365.
Pensak J. (2001) Controversies in Otolaryngology. Thieme Medical Publishing, New York, NY, 271.
Podgorsak, E. (2006) Radiation Physics for Medical Physicists, Springer, 262.
Ratanatharathorn V, Powers W, Temple T. (2004) Palliation of bone metastases. Perez C, Brady L, Halperin E. Principles and Practice of Radiation Oncology, 4th Edition, Lippincott Williams & Wilkins, Philadelphia, PA, 2392.
Ryken T, Meeks S, Traynelis V, Haller J, Bouchet L, Bova F, Pennington E, Buatti J. (2001) Ultrasonographic guidance for spinal extracranial radiosurgery: technique and application for metastatic spinal lesions. Neurosurgery Focus,11:1–6.
Saw C, Heron D, Huq S, Yue N. (2006) Target delineation and localization Part I, Medical Dosimetry, 31(1):1–2.
Szeifert GT, Kondziola D, Levivier M, Lunsford LD (eds). (2007) Radiosurgery and Pathological Fundamentals. Prog Neurological Surgery, Basel Karger, Vol. 20, 342.
Tong D, Gillick L, Hendrickson F. (1982) Palliation of symptomatic osseous metastases. Cancer, September, 50:893–899.
Tse V, Pruitt A. (2006) Metastatic disease to the spine and related structures. http://emedicine.medscape.com/article/1157987‐overview
Yamada Y, Lovelock M, Yenice K, Bilsky M, Hunt M, Zatcky, Leibel S. (2005) Multifraction image-guided and stereotactic intensity-modulated radiotherapy of paraspinal tumors: a preliminary report. International Journal of Radiation Oncology, Biology, and Physics,62:53–61.
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Haley, M., Gerszten, P.C., Burton, S.A. (2010). The Role of Radiosurgery in the Treatment of Bone Localized Cancers. In: Bone and Cancer. Topics in Bone Biology, vol 5. Springer, London. https://doi.org/10.1007/978-1-84882-019-7_16
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