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The Role of Radiosurgery in the Treatment of Bone Localized Cancers

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Part of the book series: Topics in Bone Biology ((TBB,volume 5))

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Abstract

Metastatic disease remains a significant source of morbidity for the cancer patient. Approximately 50% of patients diagnosed with cancer will develop metastases, and of these, 70% will develop symptoms [10]. Pain is the most common symptom resulting from bone metastases and is described as severe in more than 50% of hospitalized cancer patients [4].

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References

  1. Baker M. (2005) Stanford News Service, Stanford University, Stanford, CA, May 18th.

    Google Scholar 

  2. Benzil DL, Saboori M, Mogilner AY, Rochio R, Moorthy CR.(2004) Safety and efficacy of stereotactic radiosurgery for tumors of the spine. Journal of Neurosurgery,101:413–418.

    PubMed  Google Scholar 

  3. Blitzer PH. (1985) Re-analysis of the RTOG study of the palliation of symptomatic osseous metastases. Cancer, 55:1468–1472.

    Article  PubMed  CAS  Google Scholar 

  4. Brescia FJ, Portenoy RK, Ryan M, Krasnoff L, Gray G. (1992) Pain, opoid use, and survival in hospitalized patients with advanced cancer. Journal of Clinical Oncology, 10:149–155.

    PubMed  CAS  Google Scholar 

  5. Bucholz R. (2006) A look into the future: robotic radiosurgery. RT Image, Valley Forge Publishing, 9:40.

    Google Scholar 

  6. Chang E, Shiu A, Lii M, Rhines L, Mendel E, Mahajan A, Weinberg J, Mathews L, Brown B, Maor M, Cox J. (2004) Phase 1 clinical evaluation of near-simultaneous computed tomographic image-guided stereotactic radiotherapy for spinal metastases. International Journal of Radiation Oncology, Biology, and Physics,59(5):1288–1294.

    Article  Google Scholar 

  7. Chang E, Shiu A, Mendel E, Mathews L, Mahajan A, Allen P, Weinberg J, Brown B, Wang X, Woo S, Cleeland C, Maor M, Rhines L. (2007) Phase I/II study of stereotactic body radiotherapy for spinal metastasis and its pattern of failure. Journal of Neurosurgery. Spine, 7: 151–160.

    Article  PubMed  Google Scholar 

  8. Chow E, Harris K, Fan G, Tsao M, Sze W. (2007) Palliative radiotherapy trials for bone metastases: a systematic review. Journal of Clinical Oncology, 25(11):1423–1436.

    Article  PubMed  Google Scholar 

  9. Cox J, Ang K. (2003) Radiation Oncology: Rationale, Techniques, Results. 8th Edition, Mosby, St Louis, 3–4.

    Google Scholar 

  10. Cox J, Ang K. (2003) Radiation Oncology: Rationale, Technique, Results. 8th Edition, Mosby, St Louis, 954.

    Google Scholar 

  11. Emami B, Lyman J, Brown A, Coia L, Goiten M, Munzenride JE, Shank B, Solin LJ, Wessom M. (1991) Tolerance of normal tissue to therapeutic radiation. International Journal of Radiation Oncology, Biology, and Physics,21:109–122.

    CAS  Google Scholar 

  12. Enck. (2001) The Medical Care of Terminally Ill Patients. Johns Hopkins University Press, Baltimore, MD, 157.

    Google Scholar 

  13. Gerszten P, Burton S, Ozhasoglu C, Welch W. (2007) Radiosurgery for spinal metastases: clinical experience in 500 cases from a single institution. Spine, 32(2): 193–199.

    Article  PubMed  Google Scholar 

  14. Gerszten P, Welch W. (2003) Cyberknife radiosurgery for the spine. Techniques in Neurosurgery, 9:232–241.

    Article  Google Scholar 

  15. Hall E, Giaccia A. (2006) Radiobiology for the Radiologist. 6th Edition, Lippincott Williams & Wilkins, Philadelphia, PA, 11.

    Google Scholar 

  16. Hall E, Giaccia A. (2006) Radiobiology for the Radiologist. 6th Edition, Philadelphia, Lippincott Williams & Wilkins, Philadelphia, PA, 16.

    Google Scholar 

  17. Hall E, Giaccia A. (2006) Radiobiology for the Radiologist, 6th Edition, Lippincott Williams & Wilkins, Philadelphia, PA, 340.

    Google Scholar 

  18. Hall E, Giaccia A. (2006) Radiobiology for the Radiologist, 6th Edition, Philadelphia, Lippincott Williams & Wilkins, Philadelphia, PA, 342.

    Google Scholar 

  19. Hall E, Giaccia A. (2006) Radiobiology for the Radiologist, 6th Edition, Philadelphia, Lippincott Williams & Wilkins, Philadelphia, PA, 378–381.

    Google Scholar 

  20. Hartsell W, Scott C, Bruner D, Scarantino C, Ivker R, Roach M, Suh J, Demas W, Movsas B, Petersen I, Konski A, Cleeland C, Janjan N, DeSilvio M. (2005) Randomization of short- versus long-course radiotherapy for palliation of painful bony metastases. Journal of the National Cancer Institute, 97:798–804.

    Article  PubMed  Google Scholar 

  21. Heilbrun P. (2003) Cyberknife Radiosurgery: A Practical Guide, Sunnyvale, The Cyberknife Society, vii.

    Google Scholar 

  22. Khan F. (2003) The Physics of Radiation Therapy, 3rd Edition, Lippincott Williams & Wilkins, Philadelphia , PA, 28.

    Google Scholar 

  23. Khan F. (2003) The Physics of Radiation Therapy, 3rd Edition, Philadelphia, Lippincott Williams & Wilkins, Philadelphia, PA, 106.

    Google Scholar 

  24. Khan F. (2003) The Physics of Radiation Therapy, 3rd Edition, Philadelphia, Lippincott Williams & Wilkins, Philadelphia, PA, 508.

    Google Scholar 

  25. Khan F. (2003) The Physics of Radiation Therapy, 3rd Edition, Philadelphia, Lippincott Williams & Wilkins, Philadelphia, PA, 514–515.

    Google Scholar 

  26. Linear Accelerator from World of Invention. (2006) Thompson Gale, 1–3.

    Google Scholar 

  27. Lu C, Stomper P, Drislane F, Wen P, Block C, Humphrey C, Collins C, Jolesz F, Talcott J. (1998) Suspected spinal cord compression in breast cancer patients: a multidisciplinary risk assessment. Breast Cancer Research and. Treatment, 51:121–131.

    Article  PubMed  CAS  Google Scholar 

  28. Medical News Today (2007)CyberKnife Spinal Tumor Treatments Increase By 56 Percent - Success Of Non-Invasive Procedure Chronicled In The Journal Spine.February 23rd.

    Google Scholar 

  29. Mell L, Kochanski J, Roeske J, Haslam J, Mehta N, Yamada D, Hurtheau J, Collins Y, Lengyel E, Mundt A. (2006) Dosimetric predictors of acute hematologic toxicity in cervical cancer patients treated with concurrent cisplatin and intensity-modulated pelvic radiotherapy. International Journal of Radiation Oncology, Biology, and Physics,66(5):1356–1365.

    Article  Google Scholar 

  30. Pensak J. (2001) Controversies in Otolaryngology. Thieme Medical Publishing, New York, NY, 271.

    Google Scholar 

  31. Podgorsak, E. (2006) Radiation Physics for Medical Physicists, Springer, 262.

    Google Scholar 

  32. Ratanatharathorn V, Powers W, Temple T. (2004) Palliation of bone metastases. Perez C, Brady L, Halperin E. Principles and Practice of Radiation Oncology, 4th Edition, Lippincott Williams & Wilkins, Philadelphia, PA, 2392.

    Google Scholar 

  33. Ryken T, Meeks S, Traynelis V, Haller J, Bouchet L, Bova F, Pennington E, Buatti J. (2001) Ultrasonographic guidance for spinal extracranial radiosurgery: technique and application for metastatic spinal lesions. Neurosurgery Focus,11:1–6.

    Article  Google Scholar 

  34. Saw C, Heron D, Huq S, Yue N. (2006) Target delineation and localization Part I, Medical Dosimetry, 31(1):1–2.

    Article  PubMed  Google Scholar 

  35. Szeifert GT, Kondziola D, Levivier M, Lunsford LD (eds). (2007) Radiosurgery and Pathological Fundamentals. Prog Neurological Surgery, Basel Karger, Vol. 20, 342.

    Google Scholar 

  36. Tong D, Gillick L, Hendrickson F. (1982) Palliation of symptomatic osseous metastases. Cancer, September, 50:893–899.

    Article  PubMed  CAS  Google Scholar 

  37. Tse V, Pruitt A. (2006) Metastatic disease to the spine and related structures. http://emedicine.medscape.com/article/1157987‐overview

  38. Yamada Y, Lovelock M, Yenice K, Bilsky M, Hunt M, Zatcky, Leibel S. (2005) Multifraction image-guided and stereotactic intensity-modulated radiotherapy of paraspinal tumors: a preliminary report. International Journal of Radiation Oncology, Biology, and Physics,62:53–61.

    Article  Google Scholar 

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Haley, M., Gerszten, P.C., Burton, S.A. (2010). The Role of Radiosurgery in the Treatment of Bone Localized Cancers. In: Bone and Cancer. Topics in Bone Biology, vol 5. Springer, London. https://doi.org/10.1007/978-1-84882-019-7_16

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  • DOI: https://doi.org/10.1007/978-1-84882-019-7_16

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  • Print ISBN: 978-1-84882-018-0

  • Online ISBN: 978-1-84882-019-7

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