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Behçet's Syndrome

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A Clinician's Pearls and Myths in Rheumatology

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Abstract

The prevalence of Behçet's syndrome is highest in countries of the eastern Mediterranean, the Middle East, and East Asia. Aphthous oral ulcers are usually the first and most persistent clinical feature of Behçet's syndrome. Aphthous ulcers also occur frequently on the genitals (e.g., the scrotum or vulva). Uveitis — most frequently a bilateral panuveitis is common in Behçet's syndrome. Eye disease constitutes a major source of morbidity. Many forms of central nervous system disease may occur in Behçet's syndrome. These include dural sinus thrombi and white matter lesions in the midbrain and brainstem. Unlike other vasculitides, however, peripheral nervous system disease is rare. HLA-B51 is a risk factor for Behçet's syndrome.

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Authors and Affiliations

  1. University of Istanbul/Cerrahpasa Medical Faculty, Division of Rheumatology, Department of Medicine, Askaray, Istanbul 34098, Turkey Safa sok. 17/7, Kadikoy, Istanbul, 34170, Turkey

    Hasan Yazici

  2. New York University, Hospital for Joint Diseases Division of Rheumatology 246, East 20th Street New York, New York, 10003, USA

    Yusuf Yazici

Authors
  1. Hasan Yazici
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  2. Yusuf Yazici
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Editors and Affiliations

  1. Clinical Rheumatology, Massachusetts General Hospital, 55 Fruit Street / Yawkey 2, Boston, MA, 02114

    John H. Stone (Director) (Director)

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Yazici, H., Yazici, Y. (2009). Behçet's Syndrome. In: Stone, J.H. (eds) A Clinician's Pearls and Myths in Rheumatology. Springer, London. https://doi.org/10.1007/978-1-84800-934-9_22

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  • DOI: https://doi.org/10.1007/978-1-84800-934-9_22

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84800-933-2

  • Online ISBN: 978-1-84800-934-9

  • eBook Packages: MedicineMedicine (R0)

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