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Neuropsychological Assessments of Dementia in Down Syndrome and Intellectual Disabilities pp 107–127Cite as

The Cambridge Examination for Mental Disorders of Older People with Down’s Syndrome and Others with Intellectual Disabilities (CAMDEX-DS)

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References

  1. Aylward E, Burt D, Thorpe L . et al. (1997) Diagnosis of dementia in individuals with intellectual disability: Report of the task force for development of criteria for diagnosis of dementia in individuals with mental retardation. J Intellect Disabil Res 41: 152–164.

    Article  PubMed  Google Scholar 

  2. American Psychiatric Association (1994) Diagnostic and Statistical Manual of mental disorder. Washington DC: American Psychiatric Association.

    Google Scholar 

  3. World Health Organisation (1992) ICD-10 International Statistical Classification of Diseases and Related Health Problems, 10th edn. Geneva: WHO.

    Google Scholar 

  4. Roth M, Huppert FA, Mountjoy CQ . et al. (1998) CAMDEX-R: The Cambridge Examination for Mental Disorders of the Elderly (Revised). Cambridge University Press.Cambridge:

    Google Scholar 

  5. Roth M, Tym E, Mountjoy Cet al. (1986) CAMDEX—A standardised instrument for the diagnosis of mental disorder in the elderly with special reference to the early detection of dementia. Br J Psychiatry 149: 698–709.

    Article  PubMed  CAS  Google Scholar 

  6. Roth M, Huppert F, Tym E . et al. (1988) CAMDEX: The Cambridge Examination for Mental Disorder of the Elderly. Cambridge University Press.Cambridge:

    Google Scholar 

  7. Neri M, Roth M, Vreese LPDet al. (1998) The Validity of Informant Reports in Assessing the Severity of Dementia: Evidence from the CAMDEX Interview. Dement Geriatr Cogn Dis 9: 56–62.

    Article  CAS  Google Scholar 

  8. Huppert FA, Brayne C, Gill Cet al. (1995) CAMCOG—A concise neuropsychological test to assist dementia diagnosis: Socio-demographic determinants in an elderly population sample. Br J Clin Psychol 34: 529–541.

    PubMed  Google Scholar 

  9. Huppert FA, Jorm AF, Brayne Cet al. (1996) Psychometric properties of the CAMCOG and its efficacy in the diagnosis of dementia. Aging Neuropsychol Cogn 3: 201–214.

    Article  Google Scholar 

  10. Williams JG, Huppert FA, Matthews FEet al. (2003) Performance and normative values of a concise neuropsychological test (CAMCOG) in an elderly population sample. Int J Geriatr Psychiatry 18: 631–644.

    Article  PubMed  Google Scholar 

  11. Heinik J (1998) Effects of trihexyphenidyl on MMSE and CAMCOG scores of medicated elderly patients with schizophrenia. Int Psychogeriatr 10: 103–108.

    Article  PubMed  CAS  Google Scholar 

  12. Jobst K, Smith A, Szatmari Met al. (1992) Detection in life of confirmed Alzheimer’s disease using a simple measurement of medial temporal lobe atrophy by computed tomography. Lancet 340: 1179–1183.

    Article  PubMed  CAS  Google Scholar 

  13. Clarke MCJ and Anderson J (1991) The prevalence of dementia in a total population: A comparison of two screening instruments. Aging 20: 396–403.

    CAS  Google Scholar 

  14. Cullum S, Huppert FA, McGee Met al. (2000) Decline across different domains of cognitive function in normal ageing: Results of a longitudinal population-based study using CAMCOG. Int J Geriatr Psychiatry 15: 853–862.

    Article  PubMed  CAS  Google Scholar 

  15. O’Connor D, Pollitt P, Hyde Jet al. (1989) The prevalence of dementia as measured by the Cambridge Mental Disorders of the Elderly Examination. Acta Psychol Scand 79: 190–198.

    Article  Google Scholar 

  16. Schmand B, Walstra G, Lindeboom Jet al. (2000) Early detection of Alzheimer’s disease using the Cambridge Cognitive Examination (CAMCOG). Psychol Med 30: 619–627.

    Article  PubMed  CAS  Google Scholar 

  17. Heinik J, Solomesh I, and Berkman P (2004) Correlation between the CAMCOG, the MMSE, and three clock drawing tests in a specialized outpatient psychogeriatric service. Arch Gerontol Geriatr 38: 77–84.

    Article  PubMed  Google Scholar 

  18. Nielsen H, Lolk A, Andersen Ket al. (1999) Characteristics of elderly who develop Alzheimer’s disease during the next two years—A neuropsychological study using CAMCOG: The Odense Study. Int J Geriatr Psychiatry 14: 957–963.

    Article  PubMed  CAS  Google Scholar 

  19. Forstl H, Burns A, Jacoby Ret al. (1991) Neuroanatomical correlates of clinical misidentification and misperception in senile dementia of the Alzheimer type. J Clin Psychopharmacol 52: 268–271.

    CAS  Google Scholar 

  20. Gertz H, Xuereb J, Huppert Fet al. (1996) The relationship between clinical dementia and neuropathological staging (BRAAK) in a very elderly community sample. Eur Arch Psychiatry Clin Neurosci 246: 132–136.

    Article  PubMed  CAS  Google Scholar 

  21. Cabranes J, De Juan R, Encinas Met al. (2004) Relevance of functional neuroimaging in the progression of mild cognitive impairment. Neurol Res 26: 496–501.

    Article  PubMed  Google Scholar 

  22. Hunter R, McLuskie R, Wyper Pet al. (1989) The patterns of function-related cerebral blood flow investigated by single photon emission tomography with 99 m Tc-HMPAO in patients with presenile Alzheimer’s Disease and Korsakoff’s psychosis. Psychol Med 19: 847–855.

    Article  PubMed  CAS  Google Scholar 

  23. Lawton MP and Brody EM. (1969). Assessment of older people: Self-maintaining and instrumental activities of daily living. Gerontologist. 9: 179–186.

    PubMed  CAS  Google Scholar 

  24. Saxton J, McGonigle KL, Swihart AA et al. (1993) The Severe Impairment Battery. Bury St. Edmunds: Thames Valley Test Company .

    Google Scholar 

  25. Witts P and Elders S (1998) The ‘severe impairment battery’: Assessing cognitive ability in adults with Down syndrome. Br J Clin Psychol 37: 213–216.

    PubMed  Google Scholar 

  26. Ball SL, Holland AJ, Huppert FAet al. (2004) The modified CAMDEX informant interview is a valid and reliable tool for use in the diagnosis of dementia in adults with Down’s syndrome. J Intellect Disabil Res 48: 611–620.

    Article  PubMed  CAS  Google Scholar 

  27. Deb S and Braganza J (1999) Comparison of rating scales for the diagnosis of dementia in adults with Down’s syndrome. J Intellect Disabil Res 43: 400–407.

    Article  PubMed  Google Scholar 

  28. Landis JR and Koch GG (1977) The measurement of observer agreement for categorical data. Biometrics 33: 159–174.

    Article  PubMed  CAS  Google Scholar 

  29. Hon J, Huppert FA, Holland AJet al. (1999) Neuropsychological assessment of older adults with Down’s syndrome: An epidemiological study using the Cambridge Cognitive Examination (CAMCOG). Br J Clin Psychol 38: 155–165.

    Article  PubMed  Google Scholar 

  30. Folstein M, Folstein S, and McHugh P (1975) Mini-Mental State. A practical method for grading the cognitive state of patients for the clinician. J Psychol Res 12: 189–198.

    Article  CAS  Google Scholar 

  31. Hewitt KE, Carter G, and Jancar J (1985) Ageing in Down’s syndrome. Br J Psychiatry 147: 58–62.

    Article  PubMed  CAS  Google Scholar 

  32. Holland AJ, Hon J, Huppert FAet al. (1998) Population-based study of the prevalence and presentation of dementia in adults with Down’s syndrome. Br J Psychiatry 172: 493–498.

    Article  PubMed  CAS  Google Scholar 

  33. Lai F and Williams RS (1989) A prospective study of Alzheimer disease in Down syndrome. Arch Neurol 46: 849–853.

    PubMed  CAS  Google Scholar 

  34. Wisniewski KE, Wisniewski HM, and Wen GY (1985) Occurrence of neuropathological changes and dementia of Alzheimer’s disease in Down’s syndrome. Ann Neurol 17: 278–282.

    Article  PubMed  CAS  Google Scholar 

  35. Gregory CA and Hodges JR (1993) Dementia of frontal type and the focal lobar atrophies. Int Rev Psychiatry 5: 397–406.

    Article  Google Scholar 

  36. Holland AJ, Hon J, Huppert FAet al. (2000) Incidence and course of dementia in people with Down’s syndrome: Findings from a population-based study. J Intellect Disabil Res 44: 138–146.

    Article  PubMed  Google Scholar 

  37. Crome L and Stern L (1972) Pathology of Mental Retardation. Baltimore, Williams and Wilkins.MD:

    Google Scholar 

  38. Ball SL, Holland AJ, Hon Jet al. (2006) Personality and behaviour changes mark the early stages of Alzheimer’s disease in adults with Down’s syndrome: Findings from a prospective population-based study. Int J Geriatr Psychiatry 21: 661–673.

    Article  PubMed  Google Scholar 

  39. Royall DR, Cordes JA, and Polk M (1998) CLOX: An executive clock drawing task. J Neurol, Neurosurg Psychiatry 64: 588–594.

    Article  CAS  Google Scholar 

  40. Prasher VP, Farooq A, and Holder R (2004) The Adaptive Behaviour Dementia Questionnaire (ABDQ): Screening questionnaire for dementia in Alzheimer’s disease in adults with Down syndrome. Res Dev Disabil 25: 385–397.

    Article  PubMed  CAS  Google Scholar 

  41. Prasher VP, Barber PC, West Ret al. (1996) The role of magnetic resonance imaging in the diagnosis of Alzheimer disease in adults with Down syndrome. Arch Neurol 53: 1310–1313.

    PubMed  CAS  Google Scholar 

  42. Rubinsztein DC, Hon J, Stevens Fet al. (1999) Apo E genotypes and risk of dementia in Down Syndrome. Am J Med Genet B Neuropsychiatr Genet 88: 344–347.

    Article  CAS  Google Scholar 

  43. Beacher F, Simmons A, Daly Eet al. (2005) Hippocampal myo-inositol and cognitive ability in adults with Down syndrome: An in vivo proton magnetic resonance spectroscopy study. Arch Gen Psychiatry 62: 1360–1365.

    Article  PubMed  Google Scholar 

  44. Hassiotis A, Strydom A, Allen Ket al. (2003) A memory clinic for older people with intellectual disabilities. Aging Ment Health 7: 418–423.

    Article  PubMed  CAS  Google Scholar 

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Authors
  1. A.J. Holland
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  2. S.L. Ball
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    Holland, A., Ball, S. (2009). The Cambridge Examination for Mental Disorders of Older People with Down’s Syndrome and Others with Intellectual Disabilities (CAMDEX-DS). In: Prasher, V. (eds) Neuropsychological Assessments of Dementia in Down Syndrome and Intellectual Disabilities. Springer, London. https://doi.org/10.1007/978-1-84800-249-4_7

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    • DOI: https://doi.org/10.1007/978-1-84800-249-4_7

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    • Publisher Name: Springer, London

    • Print ISBN: 978-1-84800-248-7

    • Online ISBN: 978-1-84800-249-4

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