Skip to main content
SpringerLink
Log in

The Deadly Disease

  • Chapter
Chlamydia Atherosclerosis Lesion

  • 419 Accesses

Abstract

Heart attacks, strokes, and other vascular problems are among the most common diseases in the world today. They are the result of buildup of fatty gruel deposits that clog the arteries. The name of the obstructive disease is atherosclerosis, and the actual deposits are called atheroma. It is such a common disease that it would not be amiss to state that almost every person, whether old, young, male, female, the very wealthy, or the very poor, has these lesions in their arteries, to a lesser or greater extent.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Anderson RN, Kochanek KD, Murphy SL. Report of final mortality statistics, 1995. Hyattsville, Maryland: National Center for Health Statistics. Mon Vital Stat Rep 1997;45(11): suppl 2.

    Google Scholar 

  2. Huston SL, Lengerich EL, Conlisk E, et al. Morbidity and mortality weekly report. Centers for Disease Control. Trends in ischemic heart disease death for blacks and whites: United States, 1981—1995. JAMA 1999;281(1):28–29.

    Article  Google Scholar 

  3. Henderson A. Coronary heart disease: an overview. Lancet 1996;348:S1–S2.

    Article  PubMed  Google Scholar 

  4. Futterman LG, Lemberg L. Fifty per cent of patients with coronary artery disease do not have any of the conventional risk factors. Am J Crit Care 1998;7(3):240–244.

    PubMed  CAS  Google Scholar 

  5. Oliver MF. Doubts about preventing coronary heart disease. BMJ 1992;304:393–394.

    PubMed  CAS  Google Scholar 

  6. Krumholz HM, Seeman TE, Merrill SS, et al. Lack of association between cholesterol and coronary heart disease mortality and morbidity and all cause mortality in persons older than 70 years. JAMA 1994;272:1335–1340.

    Article  PubMed  CAS  Google Scholar 

  7. Sacks FM, Pasternak RC, Gibson CM, et al. Effect on coronary atherosclerosis of decrease in cholesterol concentrations in normocholesterolaemic patients. Lancet 1994;344:1182–1186.

    Article  PubMed  CAS  Google Scholar 

  8. Woolf N. Introduction. In: Crawford T (ed) Pathology of atherosclerosis. London: Butterworth, 1982:2–4.

    Google Scholar 

  9. Shattock SG. A report upon the pathological condition of the aorta of King Menephtha, traditionally regarded as the Pharaoh of the Exodus. Proc R Soc Med 1909;2:122–127.

    Google Scholar 

  10. Sandison AT. The histological examination of mummified material. Stain Technol 1955;30:277.

    PubMed  CAS  Google Scholar 

  11. Osler W. Diseases of the arteries. In: Fye WB (ed) William Osler’s collected papers on the cardiovascular system. Birmingham: The Classics of Cardiology Library, Division of Gryphon Editions, 1985:429–433.

    Google Scholar 

  12. Benditt EP. Implications of the monoclonal character of human atherosclerotic plaques. Am J Pathol 1977;86(33):693–702.

    PubMed  CAS  Google Scholar 

  13. Benditt EA, Barrett T, McDougal JK. Viruses in the etiology of atherosclerosis. Proc Natl Acad Sci U S A 1982;380:6386–6389.

    Google Scholar 

  14. Ross R. The pathogenesis of atherosclerosis: an update. N Engl J Med 1986; 314(8):488–500.

    PubMed  CAS  Google Scholar 

  15. Ross R. Atherosclerosis: a defence mechanism gone awry. Am J Pathol 1993; 143(4):987–1002.

    PubMed  CAS  Google Scholar 

  16. Ross R. Atherosclerosis: an inflammatory disease. N Engl J Med 1999;340;115–126.

    Article  PubMed  CAS  Google Scholar 

  17. Le Fanu J. The rise and fall of heart disease. In: Le Fanu J (ed) The rise and fall of modern medicine. London: Little Brown, 1999:322–350.

    Google Scholar 

  18. Gotto AM. Introduction. Symposium on hypercholesterolemia. Am J Med 1991; 91(suppl 18):1B–1S.

    Article  Google Scholar 

  19. Sacks FM, Pasternak RC, Gibson CM, et al. Effect on coronary atherosclerosis of decrease in plasma cholesterol concentration in normo-cholesterolaemic patients. Lancet 1994;344:1182–1186.

    Article  PubMed  CAS  Google Scholar 

  20. Woodard BS, Srinivasan SR, Zimny ML, et al. Electron microscopic features of lipoprotein complexes glycosaminoglycan complexes from human atherosclerotic plaques. Lab Invest 1976;34(5):516–521.

    PubMed  CAS  Google Scholar 

  21. Bhaki S. Complement and atherogenesis: the unknown connection. Editorial. Ann Med 1998;30:503–507.

    Article  Google Scholar 

  22. Hollander W, Colombo MA, Kirkpatrick B, et al. Soluble proteins in the human atherosclerotic plaque. Atherosclerosis 1979;34:391–405.

    Article  PubMed  CAS  Google Scholar 

  23. Libby P. Atheroma: more than mush. Lancet 1996;348:S4–S6.

    Article  PubMed  CAS  Google Scholar 

  24. Ford ES, De Stafano F. Risk factors for mortality from all causes and from coronary artery disease among persons with diabetes. Findings of the national health and nutrition examination survey 1. Epidemiological follow-up study. Am J Epidemiol 1991;133:1220–1230.

    PubMed  CAS  Google Scholar 

  25. La Rossa JC. Atherogenesis and its relationship to coronary risk factors. Clin Cornerstone 1998;1(1):3–14.

    Article  Google Scholar 

  26. Harjai KI. Potential new cardiovascular risk factors: left ventricular hypertrophy, homocystine, lipoprotein(a), triglycerides, oxidative stress, and fibrinogen. Ann Intern Med 1999;131:376–386.

    PubMed  CAS  Google Scholar 

  27. Hajjar KA. Homocystine-induced modulation of tissue plasminogen in patients with coronary artery disease. J Clin Invest 1993;10:2873–2879.

    Article  Google Scholar 

  28. Winder AF. Homocystine and cardiovascular disease. Editorial. J Clin Pathol 1998;51:713–715.

    Article  PubMed  CAS  Google Scholar 

  29. Forsen T, Eriksson JG, Tuomilehto J, et al. Growth in utero and during childhood among women who develop coronary heart disease: longitudinal study. BMJ 1999;319:403–407.

    Google Scholar 

  30. Bots ML, Witteman JCM, Hoffman A, et al. Low diastolic blood pressure and atherosclerosis in elderly subjects. Arch Intern Med 1996;156:844–847.

    Article  Google Scholar 

  31. Rackley CE. Estrogen and coronary artery disease in post menopausal women. Am J Med 1995;99:117–118.

    Article  PubMed  CAS  Google Scholar 

  32. Moller L, Kristensen TS. Blood lead as cardiovascular risk factor. Am J Epidemiol 1992;136:1091–1100.

    PubMed  CAS  Google Scholar 

  33. Reunanen A, Knekt P, Aran R-T. Serum ceruloplasmin level and risk of myocardial infarction and stroke. Am J Epidemiol 1992;136:1082–1090.

    PubMed  CAS  Google Scholar 

  34. Herrera CR, D’Agostino R, Gerstman BB, et al. Baldness and coronary heart disease rates in men from the Framington study. Am J Epidemiol 1995;142:828–833.

    PubMed  CAS  Google Scholar 

  35. Wilson PWF, Kannel WS. Is baldness bad for the heart? JAMA 1993;269:1035–1036.

    Article  PubMed  CAS  Google Scholar 

  36. Stehbens WE. On the “cause” of tuberculosis. Pathology 1987;19:115–119.

    Article  PubMed  CAS  Google Scholar 

  37. Chien KR. Genes and molecular physiology in genetically engineered animals. J Clin Invest 1996;97:901–909.

    Article  PubMed  CAS  Google Scholar 

  38. Plump AS, Smith JD, Hyek T. Severe hypercholesterolaemia and atherosclerosis in apo-lipoprotein E deficient mice created by homologous recombination in E S cells. Cell 1992;71:343–353.

    Article  PubMed  CAS  Google Scholar 

  39. Hajjar DP, Nicholson AC. Atherosclerosis. Am Sci 1995;83:460–467.

    Google Scholar 

  40. Henderson A. Coronary heart disease: an overview. Lancet 1996;348:Si–S2.

    Article  Google Scholar 

  41. Stary HC. Composition and classification of human atherosclerotic lesions. Virchows Arch Pathol Anat Histopathol 1992;421:277–290.

    Article  CAS  Google Scholar 

Download references

Rights and permissions

Reprints and permissions

Copyright information

© 2007 Springer-Verlag London Limited

About this chapter

Cite this chapter

(2007). The Deadly Disease. In: Chlamydia Atherosclerosis Lesion. Springer, London. https://doi.org/10.1007/978-1-84628-810-4_3

Download citation

  • DOI: https://doi.org/10.1007/978-1-84628-810-4_3

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84628-809-8

  • Online ISBN: 978-1-84628-810-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation