Skip to main content

Other Treatment Possibilities

  • Chapter
Book cover Chlamydia Atherosclerosis Lesion
  • 398 Accesses

Abstract

There are an increasing number of articles showing that existing drugs may have beneficial effects on the atheroma lesion.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 89.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Sheperd J, Blaw GJ, Murphy MB, et al. Pravastatin in elderly individuals at risk of cardiovascular disease (PROSPER) randomized trial. Lancet 2002;360:1623–1630.

    Article  Google Scholar 

  2. Volpe M, Tocci G. Integrated cardiovascular risk management for the future: lessons learned from the ASCOT trial. Aging Clin Exp Res 2005;17(4 suppl):46–53.

    PubMed  Google Scholar 

  3. Libby P, Aikawa M. Stabilization of atherosclerotic plaques: new mechanisms and clinical targets. Nat Med 2002;8(11):1257–1262.

    Article  PubMed  CAS  Google Scholar 

  4. Kurata T, Kurata M, Okada T. Cervastatin induces carotid artery plaque stabilization independently of cholesterol lowering in patients with hypercholesterolaemia. J Int Med Res 2001;29:329–334.

    PubMed  CAS  Google Scholar 

  5. Dechend R, Gieffers J, Dietz R, et al. Hydroxymethyl glutaryl coenzyme A reductase inhibition reduces Chlamydia pneumoniae-induced cell interaction and activation. Circulation 2003;108(3):261–265.

    Article  PubMed  CAS  Google Scholar 

  6. Kothe H, Dalhoff K, Rupp J, et al. Hydroxymethyl glutaryl coenzyme A reductase inhibitors modify the inflammatory response in human macrophages and endothelial cells infected with Chlamydia pneumoniae. Circulation 2000;101(15): 1760–1763.

    PubMed  CAS  Google Scholar 

  7. Erkkila L, Jauhiainen M, Laitinen K, et al. Effect of Simvastatin, an established lipidlowering drug, on pulmonary Chlamydia pneumoniae infection in mice. Antimicrob Agents Chemother 2005;49(9):3050–3062.

    Article  Google Scholar 

  8. Yin MJ, Yamamoto Y, Gaynor RB. The anti-inflammatory agents aspirin and salicylate inhibit the activity of I kappa B kinase-beta. Nature (Lond) 1998;396:77–80.

    Article  PubMed  CAS  Google Scholar 

  9. Tiran A, Gruber HJ, Graier WF, et al. Aspirin inhibits Chlamydia pneumoniaeinduced nuclear factor kappa-B activation, cytokine expression, and bacterial development in human endothelial cells. Arterioscler Thromb Vasc Biol 2002;22(7): 1075–1080.

    Article  PubMed  CAS  Google Scholar 

  10. Yoneda H, Miura K, Matshushima H, et al. Aspirin inhibits Chlamydia pneumoniae-induced NF-kappa activation, cyclo-oxygenase-2 expression and prostaglandin E2 synthesis and attenuates Chlamydia growth. J Med Microbiol 2003;52:409–415.

    Article  PubMed  CAS  Google Scholar 

  11. Fox KM. EUROPA Study. Lancet 2003;362:782–788.

    Article  PubMed  CAS  Google Scholar 

  12. Schartzkopf B. Repair of coronary arteries after treatment with perindopril in hypertensive heart disease. Hypertension 2000;36:220–251.

    Google Scholar 

  13. Pehrsson SK, Linnersjo A, Hammar N. Cancer risk in patients with ischaemic syndromes. J Int Med 2000;258(2):124–132.

    Article  Google Scholar 

  14. Hossain MS, Easmin S, Islam MS, et al. (2004) Novel thyocyanato complexes with potent cytotoxic and antimicrobial properties. J Pharm Pharmacol 2003;56(12): 1519–1525.

    Article  PubMed  CAS  Google Scholar 

  15. Coghlan A. Shapely vaccine targets: Chlamydia. New Sci 1996;152:18.

    Google Scholar 

  16. Makela PH. Is cardiovascular disease preventable by vaccination? Ann Med 1999;31(1):61–65.

    PubMed  CAS  Google Scholar 

  17. Christianen G, Pedersen A-S, Hjerno K, et al. Potential relevance of Chlamydia pneumoniae surface proteins to an effective vaccine. J Infect Dis 2000;18(suppl 3): S328–S337.

    Google Scholar 

Download references

Rights and permissions

Reprints and permissions

Copyright information

© 2007 Springer-Verlag London Limited

About this chapter

Cite this chapter

(2007). Other Treatment Possibilities. In: Chlamydia Atherosclerosis Lesion. Springer, London. https://doi.org/10.1007/978-1-84628-810-4_25

Download citation

  • DOI: https://doi.org/10.1007/978-1-84628-810-4_25

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84628-809-8

  • Online ISBN: 978-1-84628-810-4

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics