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Role of Left Ventricular Assist Devices in Acute Heart Failure Syndrome and the Future of the Replacement Heart

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Acute Heart Failure

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Abstract

The first attempts to artificially sustain the circulation in modern times occurred with the development of the cardiopulmonary bypass machine by John Gibbon and later modified by John Kirklin in the mid-1950s 1 ,2. These early machines revolutionized the field of cardiac surgery, allowing complex repairs to be done while sustaining the circulation with cardiopulmonary bypass. About a decade later, the first pulsatile pumps were being used to assist the failing left ventricle, especially in patients with cardiogenic shock postcardiotomy3,4. These early reports encouraged scientists of the time, like Dr. Michael DeBakey, in a crusade to produce a device intended for long-term ventricular support5. By the late 1960s, with the birth of heart transplantation6, interest in mechanical assist devices waned. As the limitations of heart transplantation became apparent, especially the lack of adequate immunosuppression early on, renewed interest in mechanical ways of supporting the failing heart surged in the mid-1970s.

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Author information

Authors and Affiliations

  1. Division of Cardiovascular Disease, University of Alabama at Birmingham, Birmingham, Jefferson, AL, USA

    José A. Tallaj MD, Salpy V. Pamboukian MD, MSPH & Robert C. Bourge MD

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  1. José A. Tallaj MD
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  2. Salpy V. Pamboukian MD, MSPH
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  3. Robert C. Bourge MD
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Editor information

Editors and Affiliations

  1. Department of Anesthesiology and Critical Care Medicine, Lariboisière University Hospital, Assistance Publique-Hôpitaux de Paris, Université Paris Diderot, Paris, France

    Alexandre Mebazaa MD, PhD (Professor of Medicine) (Professor of Medicine)

  2. Feinberg School of Medicine, Northwestern University, Chicago, IL, USA

    Mihai Gheorghiade MD, FACC (Professor of Medicine and Surgery, Associate Chief, Division of Cardiology and Chief, Cardiology Clinical Service) (Professor of Medicine and Surgery, Associate Chief, Division of Cardiology and Chief, Cardiology Clinical Service)

  3. Department of Cardiology Centre d’Investigation Clinique (CIC), INSERM U-684, Centre Hospitalier Universitaire, University Henri Poincaré, Nancy, France

    Faiez M. Zannad MD, PhD, FESC (Professor of Medicine) (Professor of Medicine)

  4. Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Camden, NJ, USA

    Joseph E. Parrillo MD (Professor of Medicine, Chief, Department of Medicine Edward D. Viner MD Chair, Department of Medicine and Director) (Professor of Medicine, Chief, Department of Medicine Edward D. Viner MD Chair, Department of Medicine and Director)

  5. Cooper Heart Institute, Cooper University Hospital, Camden, NJ, USA

    Joseph E. Parrillo MD (Professor of Medicine, Chief, Department of Medicine Edward D. Viner MD Chair, Department of Medicine and Director) (Professor of Medicine, Chief, Department of Medicine Edward D. Viner MD Chair, Department of Medicine and Director)

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Tallaj, J.A., Pamboukian, S.V., Bourge, R.C. (2008). Role of Left Ventricular Assist Devices in Acute Heart Failure Syndrome and the Future of the Replacement Heart. In: Mebazaa, A., Gheorghiade, M., Zannad, F.M., Parrillo, J.E. (eds) Acute Heart Failure. Springer, London. https://doi.org/10.1007/978-1-84628-782-4_67

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  • DOI: https://doi.org/10.1007/978-1-84628-782-4_67

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