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Penis Carcinoma: Introduction

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References

  1. American cancer society detailed guide: penile cancer. What are the key statistics about penile cancer? http://www.cancer.org/docroot/CRI/content/CRI_2_4_1X_What_are_the_key_statistics_for_penile_cancer. Accessed August 2005.

  2. Schoen EJ. The status of circumcision of newborns. N Engl J Med. 1990;322(18):1308–12.

    PubMed  CAS  Google Scholar 

  3. Brinton LA, Li JY, Rong SD, et al. Risk factors for penile cancer: results from a case-control study in China. Int J Cancer. 1991;47(4):504–9.

    PubMed  CAS  Google Scholar 

  4. Melmed EP, Pyne JR. Carcinoma of the penis in a Jew circumcised in infancy. Br J Surg. 1967;54(8):729–31.

    PubMed  CAS  Google Scholar 

  5. Kochen M, McCurdy S. Circumcision and the risk of cancer of the penis. A life-table analysis. Am J Dis Child. 1980;134(5):484–6.

    PubMed  CAS  Google Scholar 

  6. Dillner J, von Krogh G, Horenblas S, et al. Etiology of squamous cell carcinoma of the penis. Scand J Urol Nephrol. 2000;205 Suppl:189–93.

    Google Scholar 

  7. Maden C, Sherman KJ, Beckmann AM, et al. History of circumcision, medical conditions, and sexual activity and risk of penile cancer. J Natl Cancer Inst. 1993;85(1):19–24.

    PubMed  CAS  Google Scholar 

  8. Tseng HF, Morgenstern H, Mack T, et al. Risk factors for penile cancer: results of a population-based case-control study in Los Angeles County (United States). Cancer Causes Control. 2001;12:267–77.

    Google Scholar 

  9. Hellberg D, Valentin J, Eklund T, et al. Penile cancer: is there an epidemiological role for smoking and sexual behaviour? Br Med J (Clin Res Ed). 1987;295(6609):1306–8.

    CAS  Google Scholar 

  10. Reddy CR, Devendranath V, Pratap S. Carcinoma of the penis-role of phimosis. Urology. 1984;24(1):85–8.

    PubMed  CAS  Google Scholar 

  11. Bain L, Geronemus R. The association of lichen planus of the penis with squamous cell carcinoma in situ and with verrucous squamous carcinoma. J Dermatol Surg Oncol. 1989;15(4):413–7.

    PubMed  CAS  Google Scholar 

  12. Powell JJ, Wojnarowska F. Lichen sclerosus. Lancet. 1999;353(9166):1777–83.

    PubMed  CAS  Google Scholar 

  13. Bissada NK, Morcos RR, el-Senoussi M. Post-circumcision carcinoma of the penis. I. Clinical aspects. J Urol. 1986;135(2):283–5.

    PubMed  CAS  Google Scholar 

  14. Daling JR, Sherman KJ, Hislop TG, et al. Cigarette smoking and the risk of anogenital cancer. Am J Epidemiol. 1992;135(2):180–9.

    PubMed  CAS  Google Scholar 

  15. Harish K, Ravi R. The role of tobacco in penile carcinoma. Br J Urol. 1995;75(3):375–7.

    PubMed  CAS  Google Scholar 

  16. Daling JR, Madeleine MM, Johnson LG, et al. Penile cancer: importance of circumcision, human papillomavirus and smoking in in situ and invasive disease. Int J Cancer. 2005;116:606–16.

    PubMed  CAS  Google Scholar 

  17. Stern RS. Genital tumors among men with psoriasis exposed to psoralens and ultraviolet A radiation (PUVA) and ultraviolet B radiation. The photochemotherapy follow-up study. N Engl J Med. 1990;322(16):1093–7.

    PubMed  CAS  Google Scholar 

  18. Aubin F, Puzenat E, Arveux P, et al. Genital squamous cell carcinoma in men treated by photochemotherapy. A cancer registry-based study from 1978 to 1998. Br J Dermatol. 2001;144(6):1204–6.

    PubMed  CAS  Google Scholar 

  19. Martinez I. Relationship of squamous cell carcinoma of the cervix uteri to squamous cell carcinoma of the penis among Puerto Rican women married to men with penile carcinoma. Cancer. 1969;24(4):777–80.

    PubMed  CAS  Google Scholar 

  20. Graham S, Priore R, Graham M, et al. Genital cancer in wives of penile cancer patients. Cancer. 1979;44(5):1870–4.

    PubMed  CAS  Google Scholar 

  21. Cocks PS, Peel KR, Cartwright RA, et al. Carcinoma of penis and cervix. Lancet. 1980;2(8199):855–6.

    PubMed  CAS  Google Scholar 

  22. Cocks PS, Adib RS, Hunt KM. Concurrent carcinoma of penis and carcinoma-in situ of the cervix in a married couple. Case report. Br J Obstet Gynaecol. 1982;89(5):408–9.

    PubMed  CAS  Google Scholar 

  23. Hellberg D, Nilsson S. Genital cancer among wives of men with penile cancer. A study between 1958 and 1982. Br J Obstet Gynaecol. 1989;96(2):221–5.

    PubMed  CAS  Google Scholar 

  24. Maiche AG, Pyrhonen S. Risk of cervical cancer among wives of men with carcinoma of the penis. Acta Oncol. 1990;29(5):569–71.

    PubMed  CAS  Google Scholar 

  25. Iversen T, Tretli S, Johansen A, et al. Squamous cell carcinoma of the penis and of the cervix, vulva and vagina in spouses: is there any relationship? An epidemiological study from Norway, 1960–92. Br J Cancer. 1997;76(5):658–60.

    PubMed  CAS  Google Scholar 

  26. Hemminki K, Dong C. Cancer in husbands of cervical cancer patients. Epidemiology. 2000;11(3):347–9.

    PubMed  CAS  Google Scholar 

  27. Zderic SA, Carpiniello VL, Malloy TR, et al., Urological applications of human papillomavirus typing using deoxyribonucleic acid probes for the diagnosis and treatment of genital condyloma. J Urol. 1989;141(1):63–5.

    PubMed  CAS  Google Scholar 

  28. Mandell GL, Bennett JE, Dolin R. Mandell, Douglas, and Bennett’s principles and practice of infectious diseases; Churchill Livingstone. 2000.

    Google Scholar 

  29. Ferreux E, Lont AP, Horenblas S, et al. Evidence for at least three alternative mechanisms targeting the p16^INK4A/cyclin D/Rb pathway in penile carcinoma, one of which is mediated by high-risk human papillomavirus. J Pathol. 2003;201:109–18.

    PubMed  CAS  Google Scholar 

  30. Bezerra ALR, Lopes A, Santiagao GH, et al. Human papillomavirus as a prognostic factor in carcinoma of the penis: analysis of 82 patients treated with amputation and bilateral lymphadenectomy. Cancer. 2001;91:2315–21.

    PubMed  CAS  Google Scholar 

  31. Patterson JW, Kao GF, Graham JH, et al. Bowenoid papulosis. A clinicopathologic study with ultrastructural observations. Cancer. 1986;57(4):823–36.

    PubMed  CAS  Google Scholar 

  32. Su CK, Shipley WU. Bowenoid papulosis: a benign lesion of the shaft of the penis misdiagnosed as squamous carcinoma. J Urol. 1997;157(4):1361–2.

    PubMed  CAS  Google Scholar 

  33. Zelickson AS, Prawer SE. Bowenoid papulosis of the penis. Demonstration of intranuclear viral-like particles. Am J Dermatopathol. 1980;2(4):305–8.

    PubMed  CAS  Google Scholar 

  34. Dore B, Grange P, Irani J, et al. Atrophicus sclerosis lichen and cancer of the glans. J Urol. 1989;95(7):415–8.

    CAS  Google Scholar 

  35. Campus GV, Alia F, Bosincu L. Squamous cell carcinoma and lichen sclerosus et atrophicus of the prepuce. Plast Reconstr Surg. 1992;89(5):962–4.

    PubMed  CAS  Google Scholar 

  36. Pride HB, Miller OF III, Tyler WB. Penile squamous cell carcinoma arising from balanitis xerotica obliterans. J Am Acad Dermatol. 1993;29(3):469–73.

    PubMed  CAS  Google Scholar 

  37. Simonart T, Noel JC, De Dobbeleer G, et al. Carcinoma of the glans penis arising 20 years after lichen sclerosus. Dermatology. 1998;196(3):337–8.

    PubMed  CAS  Google Scholar 

  38. Lowe FC, McCullough AR. Cutaneous horns of the penis: an approach to management. Case report and review of the literature. J Am Acad Dermatol. 1985;13(2 Pt 2):369–73.

    PubMed  CAS  Google Scholar 

  39. Raghavaiah NV, Soloway MS, Murphy WM. Malignant penile horn. J Urol. 1977;118(6):1068–9.

    PubMed  CAS  Google Scholar 

  40. Fields T, Drylie D, Wilson J. Malignant evolution of penile horn. Urology. 1987;30(1):65–6.

    PubMed  CAS  Google Scholar 

  41. Goldstein HH. Cutaneous horns of the penis. J Urol. 1933;30:367–74.

    Google Scholar 

  42. Winterhoff E, Sparks JA. Penile horn. J Urol. 1951;66(5):704–7.

    PubMed  CAS  Google Scholar 

  43. Sheen MC, Sheu HM, Huang CH, et al. Penile verrucous carcinoma successfully treated by intra-aortic infusion with methotrexate. Urology. 2003;61:1216–20.

    PubMed  Google Scholar 

  44. Mikhail GR. Cancers, precancers, and pseudocancers on the male genitalia. A review of clinical appearances, histopathology, and management. J Dermatol Surg Oncol. 1980;6(12):1027–35.

    PubMed  CAS  Google Scholar 

  45. Grabstald H, Kelley CD. Radiation therapy of penile cancer: six to ten-year follow-up. Urology. 1980;15(6):575–6.

    PubMed  CAS  Google Scholar 

  46. Goette DK, Elgart M, DeVillez RL. Erythroplasia of Queyrat. Treatment with topically applied fluorouracil. JAMA. 1975;232(9):934–7.

    PubMed  CAS  Google Scholar 

  47. Goette DK, Carson TE. Erythroplasia of Queyrat: treatment with topical 5-fluorouracil. Cancer. 1976;38(4):1498–502.

    PubMed  CAS  Google Scholar 

  48. Schroeder TL, Sengelmann R. Squamous cell carcinoma in situ of the penis successfully treated with imiquimod 5% cream. J Am Acad Dermatol. 2002;46:545–8.

    PubMed  Google Scholar 

  49. Madej G, Meyza J. Cryosurgery of penile carcinoma. Short report on preliminary results. Oncology. 1982;39(6):350–2.

    PubMed  CAS  Google Scholar 

  50. Rosemberg SK, Fuller TA. Carbon dioxide rapid superpulsed laser treatment of erythroplasia of Queyrat. Urology. 1980;16(2):181–2.

    PubMed  CAS  Google Scholar 

  51. Rosemberg SK. Carbon dioxide laser treatment of external genital lesions. Urology. 1985;25(6):555–8.

    PubMed  CAS  Google Scholar 

  52. Landthaler M, Haina D, Brunner R, et al. Laser therapy of Bowenoid papulosis and Bowen’s disease. J Dermatol Surg Oncol. 1986;12(12):253–1257.

    Google Scholar 

  53. Moore SW, Wheeler JE, Hefter LG. Epitheloid sarcoma masquerading as Peyronie’s disease. Cancer. 1975;35(6):1706–10.

    PubMed  CAS  Google Scholar 

  54. Mabogunje O. Kaposi sarcoma of glans penis. Urology. 1981;17(5):476–8.

    PubMed  CAS  Google Scholar 

  55. Parsons MA, Fox M. Malignant fibrous histiocytoma of the penis. Eur Urol. 1988;14(1):75–6.

    PubMed  CAS  Google Scholar 

  56. Rasbridge SA, Parry JR. Angiosarcoma of the penis. Br J Urol. 1989;63(4):440–1.

    PubMed  CAS  Google Scholar 

  57. Manivel JC, Fraley EE. Malignant melanoma of the penis and male urethra: 4 case reports and literature review. J Urol. 1988;139(4):813–6.

    PubMed  CAS  Google Scholar 

  58. de Bree E, Sanidas E, Tzardi M, et al. Malignant melanoma of the penis. Eur J Surg Oncol. 1997;23(3):277–9.

    PubMed  Google Scholar 

  59. Goldminz D, Scott G, Klaus S. Penile basal cell carcinoma. Report of a case and review of the literature. J Am Acad Dermatol. 1989;20(6):1094–7.

    PubMed  CAS  Google Scholar 

  60. Ladocsi LT, Siebert CF Jr, Rickert RR, et al. Basal cell carcinoma of the penis. Cutis. 1998;61(1):25–7.

    PubMed  CAS  Google Scholar 

  61. Dalkin B, Zaontz MR. Rhabdomyosarcoma of the penis in children. J Urol. 1989;141(4):908–9.

    PubMed  CAS  Google Scholar 

  62. Srinivas V, Morse MJ, Herr HW, et al. Penile cancer: relation of extent of nodal metastasis to survival. J Urol. 1987;137(5):880–2.

    PubMed  CAS  Google Scholar 

  63. Solsona E, Iborra I, Ricos JV, et al. Corpus cavernosum invasion and tumor grade in the prediction of lymph node condition in penile carcinoma. Eur Urol. 1992;22(2):115–8.

    PubMed  CAS  Google Scholar 

  64. Ayyappan K, Ananthakrishnan N, Sankaran V. Can regional lymph node involvement be predicted in patients with carcinoma of the penis? Br J Urol. 1994;73(5):549–53.

    PubMed  CAS  Google Scholar 

  65. Lopes A, Rossi BM, Fonseca FP, et al. Unreliability of modified inguinal lymphadenectomy for clinical staging of penile carcinoma. Cancer. 1996;77(10):2099–102.

    PubMed  CAS  Google Scholar 

  66. Beggs JH, Spratt JS Jr. Epidermoid carcinoma of the penis. J Urol. 1964; 91(2):166–72.

    PubMed  CAS  Google Scholar 

  67. Hardner GJ, Bhanalaph T, Murphy GP, et al. Carcinoma of the penis: analysis of therapy in 100 consecutive cases. J Urol. 1972;108(3):428–30.

    PubMed  CAS  Google Scholar 

  68. Kossow JH, Hotchkiss RS, Morales PA. Carcinoma of penis treated surgically. Analysis of 100 cases. Urology. 1973;2(2):169–72.

    CAS  Google Scholar 

  69. Ekstrom T, Edsmyr F. Cancer of the penis: a clinical study of 229 cases. Acta Chir Scand. 1958;115:25–9.

    PubMed  CAS  Google Scholar 

  70. Johnson DE, Lo RK. Management of regional lymph nodes in penile carcinoma. Five-year results following therapeutic groin dissections. Urology. 1984;24(4):308–11.

    PubMed  CAS  Google Scholar 

  71. McDougal WS, Kirchner FK Jr, Edwards RH, et al. Treatment of carcinoma of the penis: the case for primary lymphadenectomy. J Urol. 1986;136(1):38–41.

    PubMed  CAS  Google Scholar 

  72. Ravi R. Prophylactic Lymphadenectomy vs observation vs inguinal biopsy in node-negative patients with invasive carcinoma of the penis. Jpn J Clin Oncol. 1993;23(1):53–8.

    PubMed  CAS  Google Scholar 

  73. Ornellas AA, Seixas AL, Marota A, et al. Surgical treatment of invasive squamous cell carcinoma of the penis: retrospective analysis of 350 cases. J Urol. 1994;151(5):1244–9.

    PubMed  CAS  Google Scholar 

  74. Staubitz WJ, Lent MH, Mack FG, et al. Carcinoma of the penis. Cancer. 1955;8:371.

    PubMed  CAS  Google Scholar 

  75. Johnson DE, Fuerst DE, Ayala AG. Carcinoma of the penis. Experience with 153 cases. Urology. 1973;1(5):404–8.

    PubMed  CAS  Google Scholar 

  76. Gursel EO, Georgountzos C, Uson AC, et al. Penile cancer. Urology. 1973;1(6):569–78.

    PubMed  CAS  Google Scholar 

  77. Broders AC. Squamous cell epithelium of the skin. Ann Surg. 1921;73:141–3.

    PubMed  CAS  Google Scholar 

  78. Maiche AG, Pyrhonen S, Karkinen M. Histological grading of squamous cell carcinoma of the penis: a new scoring system. Br J Urol. 1991;67(5):522–6.

    PubMed  CAS  Google Scholar 

  79. McDougal WS. Carcinoma of the penis: improved survival by early regional lymphadenectomy based on the histological grade and depth of invasion of the primary lesion. J Urol. 1995;154(4):1364–6.

    PubMed  CAS  Google Scholar 

  80. Cubilla AL, Barreto J, Caballero C, et al. Pathologic features of epidermoid carcinoma of the penis. A prospective study of 66 cases. Am J Surg Pathol. 1993;17(8):753–63.

    PubMed  CAS  Google Scholar 

  81. Theodorescu D, Russo P, Zhang ZF, et al. Outcomes of initial surveillance of invasive squamous cell carcinoma of the penis and negative nodes. J Urol. 1996;155(5):1626–31.

    PubMed  CAS  Google Scholar 

  82. Heyns CF, Vollenhoven PV, Steenkamp JW, et al. Carcinoma of the penis-appraisal of a modified tumour-staging system. Br J Urol. 1997;80(2):307–12.

    PubMed  CAS  Google Scholar 

  83. Yamashita T, Ogawa A. Ultrasound in penile cancer. Urol Radiol. 1989;11(3):174–7.

    PubMed  CAS  Google Scholar 

  84. Dorak AC, Ozkan GA, Tamac NI, et al. Ultrasonography in the recognition of penile cancer. J Clin Ultrasound. 1992;20(9):624–6.

    PubMed  CAS  Google Scholar 

  85. Herbener TE, Seftel AD, Nehra A, et al. Penile ultrasound. Semin Urol. 1994;12(4):320–32.

    PubMed  CAS  Google Scholar 

  86. Horenblas S, Kroger R, Gallee MP, et al. Ultrasound in squamous cell carcinoma of the penis; a useful addition to clinical staging? A comparison of ultrasound with histopathology. Urology. 1994;43(5):702–7.

    PubMed  CAS  Google Scholar 

  87. Lont AP, Besnard AP, Gallee MP, et al. A comparison of physical examination and imaging in determining the extent of primary penile carcinoma. BJU Int. 2003;91(6):493–5.

    PubMed  CAS  Google Scholar 

  88. Hricak H, Marotti M, Gilbert TJ, et al. Normal penile anatomy and abnormal penile conditions: evaluation with MR imaging. Radiology. 1988;169(3):683–90.

    PubMed  CAS  Google Scholar 

  89. Kawada T, Hashimoto K, Tokunaga T, et al. Two cases of penile cancer: magnetic resonance imaging in the evaluation of tumor extension. J Urol. 1994; 152(3):963–5.

    PubMed  CAS  Google Scholar 

  90. de Kerviler E, Ollier P, Desgrandchamps F, et al. Magnetic resonance imaging in patients with penile carcinoma. Br J Radiol. 1995;68(811):704–11.

    PubMed  Google Scholar 

  91. Kageyama S, Ueda T, Kushima R, et al. Primary adenosquamous cell carcinoma of the male distal urethra: magnetic resonance imaging using a circular surface coil. J Urol. 1997;158(5):1913–4.

    PubMed  CAS  Google Scholar 

  92. Tabatabaei S, Harisinghani M, McDougal WS. Regional lymph node staging using lymphotropic nanoparticle enhanced magnetic resonance imaging with ferumoxtran-10 in patients with penile cancer. J Urol. 2005;174(3):923–7.

    PubMed  Google Scholar 

  93. Jackson SM. The treatment of carcinoma of the penis. Br J Surg. 1966;53(1):33–5.

    PubMed  CAS  Google Scholar 

  94. Mohs FE. Chemosurgery: microscopically controlled surgery for skin cancer-past, present and future. J Dermatol Surg Oncol. 1978;4(1):41–54.

    PubMed  CAS  Google Scholar 

  95. Mohs FE, Snow SN, Messing EM, et al. Microscopically controlled surgery in the treatment of carcinoma of the penis. J Urol. 1985;133(6):961–6.

    PubMed  CAS  Google Scholar 

  96. Mohs FE, Snow SN, Larson PO. Mohs micrographic surgery for penile tumors. Urol Clin North Am. 1992;19(2):291–304.

    PubMed  CAS  Google Scholar 

  97. Farrell AM, Dawber RP. Squamous cell carcinoma of the penis. J Am Acad Dermatol. 1998;38(3):504–5.

    PubMed  CAS  Google Scholar 

  98. Frimberger D, Hungerhuber E, Zaak D, et al. Penile carcinoma. Is Nd:YAG laser therapy radical enough? J Urol. 2002;168(6):2418–21.

    CAS  Google Scholar 

  99. Zouhair A, Coucke PA, Jeanneret W, et al. Radiation therapy alone or combined surgery and radiation therapy in squamous-cell carcinoma of the penis? Eur J Cancer. 2001;37(2):198–203.

    PubMed  CAS  Google Scholar 

  100. Kiltie AE, Elwell C, Close HJ, et al. Iridium-192 implantation for node-negative carcinoma of the penis: the Cookridge Hospital experience. Clin Oncol. 2000;12(1):25–31.

    CAS  Google Scholar 

  101. Crook J, Grimard L, Tsihlias J, et al. Interstitial brachytherapy for penile cancer: an alternative to amputation. J Urol. 2002;167(2 Pt 1):506–11.

    PubMed  Google Scholar 

  102. Crook JM, Jezioranski J, Math M, et al. Penile brachytherapy: results for 49 patients. Int J Radiat Oncol Biol Phys. 2005;62(2):460–7.

    PubMed  Google Scholar 

  103. Agrawal A, Pai D, Ananthakrishnan N, et al. The histological extent of the local spread of carcinoma of the penis and its therapeutic implications. BJU Int. 2000;85:299–301.

    PubMed  CAS  Google Scholar 

  104. Hanash KA, Furlow WL, Utz DC, et al. Carcinoma of the penis: a clinicopathologic study. J Urol. 1970;104(2):291–7.

    PubMed  CAS  Google Scholar 

  105. Jensen MO. Cancer of the penis in Denmark 1942 to 1962(511 cases). Dan Med Bull. 1977;24(2):66–72.

    PubMed  CAS  Google Scholar 

  106. Opjordsmoen S, Fossa SD. Quality of life in patients treated for penile cancer. A follow-up study. Br J Urol. 1994;74(5):652–7.

    PubMed  CAS  Google Scholar 

  107. Opjordsmoen S, Waehre H, Aass N, et al. Sexuality in patients treated for penile cancer: patients’ experience and doctors judgement. Br J Urol. 1994;73(5):554–60.

    PubMed  CAS  Google Scholar 

  108. Bissada NK, Yakout HH, Fahmy WE, et al. Multi-institutional long-term experience with conservative surgery for invasive penile carcinoma. J Urol. 2003;169:500–2.

    PubMed  Google Scholar 

  109. Pietrzak P, Corbishley C, Watkin N. Ogran-sparing surgery for invasive penile cancer: early follow-up data. BJU Int. 2004;94:1253–7.

    PubMed  Google Scholar 

  110. McDougal WS. Phallic preserving surgery in patients with invasive squamous cell carcinoma of the penis. J Urol. 2005;174(6):2218–20.

    PubMed  Google Scholar 

  111. Fraley EE, Zhang G, Manivel C, et al. The role of ilioinguinal lymphadenectomy and significance of histological differentiation in treatment of carcinoma of the penis. J Urol. 1989;142(6):1478–82.

    PubMed  CAS  Google Scholar 

  112. Horenblas S, van Tinteren H. Squamous cell carcinoma of the penis. IV. Prognostic factors of survival: analysis of tumor, nodes and metastasis classification system. J Urol. 1994;151(5):1239–43.

    PubMed  CAS  Google Scholar 

  113. Skinner DG, Leadbetter WF, Kelley SB. The surgical management of squamous cell carcinoma of the penis. J Urol. 1972;107(2):273–7.

    PubMed  CAS  Google Scholar 

  114. Lopes A, Hidalgo GS, Kowalski LP, et al. Prognostic factors in carcinoma of the penis: multivariate analysis of 145 patients treated with amputation and lymphadenectomy. J Urol. 1996;156(5):1637–42.

    PubMed  CAS  Google Scholar 

  115. Horenblas S, van Tinteren H, Delemarre JF, et al. Squamous cell carcinoma of the penis. III. Treatment of regional lymph nodes. J Urol. 1993;149(3):492–7.

    PubMed  CAS  Google Scholar 

  116. Fegen P, Persky L. Squamous cell carcinoma of the penis: its treatment, with special reference to radical node dissection. Arch Surg. 1969;99(1):117–20.

    PubMed  CAS  Google Scholar 

  117. Cabanas RM. An approach for the treatment of penile carcinoma. Cancer. 1977;39(2):456–66.

    PubMed  CAS  Google Scholar 

  118. Cabanas RM. Anatomy and biopsy of sentinel lymph nodes. Urol Clin North Am. 1992;19(2):267–76.

    PubMed  CAS  Google Scholar 

  119. Cabanas RM. Application of the sentinel node concept in urogenital cancer. Recent Results Cancer Res. 2000;157:141–9.

    PubMed  CAS  Google Scholar 

  120. Perinetti E, Crane DB, Catalona WJ. Unreliability of sentinel lymph node biopsy for staging penile carcinoma. J Urol. 1980;124(5):734–5.

    PubMed  CAS  Google Scholar 

  121. Wespes E, Simon J, Schulman CC. Cabanas approach: is sentinel node biopsy reliable for staging penile carcinoma? Urology. 1986;28(4):278–9.

    PubMed  CAS  Google Scholar 

  122. Srinivas V, Joshi A, Agarwal B, et al. Penile cancer-the sentinel lymph node controversy. Urol Int. 1991;47(2):108–9.

    PubMed  CAS  Google Scholar 

  123. Pettaway CA, Pisters LL, Dinney CP, et al. Sentinel lymph node dissection for penile carcinoma: the M.D. Anderson Cancer Center experience. J Urol. 1995;154(6):1999–2003.

    PubMed  CAS  Google Scholar 

  124. Morton DL, Wen DR, Wong JH, et al. Technical details of intraoperative lymphatic mapping for early stage melanoma. Arch Surg. 1992;127(4):392–9.

    PubMed  CAS  Google Scholar 

  125. Han KR, Brogle BN, Goydos J, et al. Lymphatic mapping and intraoperative lymphoscintigraphy for identifying the sentinel node in penile tumors. Urology. 2000;55(4):582–5.

    PubMed  CAS  Google Scholar 

  126. Valdes Olmos RA, Tanis PJ, Hoefnagel CA, et al. Penile lymphoscintigraphy for sentinel node identification. Eur J Nucl Med. 2001;28(5):581–5.

    PubMed  CAS  Google Scholar 

  127. Tanis PJ, Lont AP, Meinhardt W, et al. Dynamic sentinel node biopsy for penile cancer: reliability of a staging technique. J Urol. 2002;168(1):76–80.

    PubMed  CAS  Google Scholar 

  128. Horenblas S, Jansen L, Meinhardt W, et al. Detection of occult metastasis in squamous cell carcinoma of the penis using a dynamic sentinel node procedure. J Urol. 2000;163(1):100–4.

    PubMed  CAS  Google Scholar 

  129. Tanis PJ, Lont AP, Meinhardt W, et al. Dynamic sentinel node biopsy for penile cancer: reliability of a staging technique. J Urol. 2002;168:76–80.

    PubMed  CAS  Google Scholar 

  130. Lont AP, Horenblas S, Tanis PJ, et al. Management of clinically node negative penile carcinoma: improved survival after the introduction of dynamic sentinel node biopsy. J Urol. 2003;170:783–6.

    PubMed  CAS  Google Scholar 

  131. Kroon BK, Horenblas S, Deurloo EE, et al. Ultrasonography-guided fine-needle aspiration cytology before sentinel node biopsy in patients with penile carcinoma. BJU Int. 2005;95:517–21.

    PubMed  Google Scholar 

  132. Martins ACP, Faria SM, Cologna AJ, et al. Immunoexpression of p53 protein and proliferating cell nuclear antigen in penile carcinoma. J Urol. 2002;167:89–93.

    PubMed  CAS  Google Scholar 

  133. Lopes A, Bezerra ALR, Pinto CAL, et al. p53 as a new prognostic factor for lymph node metastasis in penile carcinoma: analysis of 82 patients treated with amputation and bilateral lymphadenectomy. J Urol. 2002;168:81–6.

    PubMed  Google Scholar 

  134. Berdjis N, Meye A, Nippgen J, et al. Expression of Ki-67 in squamous cell carcinoma of the penis. BJU Int. 2005;96:146–8.

    PubMed  CAS  Google Scholar 

  135. Laniado ME, Lowdell C, Mitchell H, et al. Squamous cell carcinoma antigen: a role in the early identification of nodal metastases in men with squamous cell carcinoma of the penis. BJU Int. 2003;92:248–50.

    PubMed  CAS  Google Scholar 

  136. Kroon BK, Horenblas S, Lont AP, et al. Patients with penile carcinoma benefit from immediate resection of clinically occult lymph node metastases. J Urol. 2005;173(3):816–9.

    PubMed  CAS  Google Scholar 

  137. Ornellas AA, Seixas AL, de Moraes JR. Analyses of 200 lymphadenectomies in patients with penile carcinoma. J Urol. 1991;146(2):330–2.

    Google Scholar 

  138. Kamat MR, Kulkarni JN, Tongaonkar HB. Carcinoma of the penis: the Indian experience. J Surg Oncol. 1993;52(1):50–5.

    PubMed  CAS  Google Scholar 

  139. Ravi R. Morbidity following groin dissection for penile carcinoma. Br J Urol. 1993;72(6):941–5.

    PubMed  CAS  Google Scholar 

  140. Johnson DE, Lo RK. Complications of groin dissection in penile cancer. Experience with 101 lymphadenectomies. Urology. 1984;24(4):312–4.

    PubMed  CAS  Google Scholar 

  141. Bevan-Thomas R, Slaton JW, Pettaway CA. Contemporary morbidity from lymphadenectomy for penile squamous cell carcinoma: the M.D. Anderson Cancer Center Experience. J Urol. 2002;167(4):1638–42.

    PubMed  Google Scholar 

  142. Nelson BA, Cookson MS, Smith JA, et al. Complications of inguinal and pelvic lymphadenectomy for squamous cell carcinoma of the penis: a contemporary series. J Urol. 2004;172:494–7.

    PubMed  Google Scholar 

  143. Graham SD, Kean TE, Glenn JF. Glenns Urologic Surgery. 6th ed. Philadelphia: Lippincott Williams & Wilkins; 2004.

    Google Scholar 

  144. Tabatabaei S, McDougal WS. Primary skin closure of large groin defects after inguinal lymphadenectomy for penile cancer using an abdominal cutaneous advancement flap. J Urol. 2003;169(1):118–20.

    PubMed  Google Scholar 

  145. el-Demiry MI, Oliver RT, Hope-Stone HF, et al. Reappraisal of the role of radiotherapy and surgery in the management of carcinoma of the penis. Br J Urol. 1984;56(6):724–8.

    PubMed  CAS  Google Scholar 

  146. Vaeth JM, Green JP, Lowy RO. Radiation therapy of carcinoma of the penis. Am J Roentgenol Radium Ther Nucl Med. 1970;108(1):130–5.

    PubMed  CAS  Google Scholar 

  147. Pizzocaro G, Piva L. Adjuvant and neoadjuvant vincristine, bleomycin, and methotrexate for inguinal metastases from squamous cell carcinoma of the penis. Acta Oncol. 1988;27(6b):823–4.

    PubMed  CAS  Google Scholar 

  148. Hussein AM, Benedetto P, Sridhar KS. Chemotherapy with cisplatin and 5-fluorouracil for penile and urethral squamous cell carcinomas. Cancer. 1990;65(3):433–8.

    PubMed  CAS  Google Scholar 

  149. Dexeus FH, Logothetis CJ, Sella A, et al. Combination chemotherapy with methotrexate, bleomycin and cisplatin for advanced squamous cell carcinoma of the male genital tract. J Urol. 1991;146(5):1284–7.

    PubMed  CAS  Google Scholar 

  150. Shammas FV, Ous S, Fossa SD. Cisplatin and 5-fluorouracil in advanced cancer. J Urol. 1992;147(3):630–2.

    PubMed  CAS  Google Scholar 

  151. Forero L, Patnaik A, Hammond LA, et al. Phase I, pharmacokinetic (PK) and biologic study of OSI-774, a selective epidermal growth factor receptor (EGFR) tyrosine kinase (TK) inhibitor in combination with paclitaxel and carboplatin. 2002 ASCO Annual Meeting, abstract no.1908.

    Google Scholar 

  152. Golijanin D, Tan JY, Kazior A, et al. Cyclooxygenase-2 and microsomal prostaglandin E synthase-1 are overexpressed in squamous cell carcinoma of the penis. Clin Cancer Res. 2004;10:1024–31.

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street GRB-1102, Boston, MA 02114–2696

    D. M. Rodin

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  1. D. M. Rodin
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  2. S. Tabatabaei
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  3. W. S. McDougal
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Editors and Affiliations

  1. Department of Urology, Academic Medical Center, Amsterdam, The Netherlands

    Jean J.M.C.H. de la Rosette  & Hessel Wijkstra  & 

  2. Department of Urology, The George Washington University, Washington, USA

    Michael J. Manyak

  3. Department of Radiology, Massachusetts General Hospital, Boston, DC, USA

    Mukesh G. Harisinghani

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Rodin, D.M., Tabatabaei, S., McDougal, W.S. (2009). Penis Carcinoma: Introduction. In: de la Rosette, J.J., Manyak, M.J., Harisinghani, M.G., Wijkstra, H. (eds) Imaging in Oncological Urology. Springer, London. https://doi.org/10.1007/978-1-84628-759-6_30

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