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Magnesium and Osteoporosis

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New Perspectives in Magnesium Research

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Abstract

Magnesium is the second most abundant cation in bone and has been recognized as one of essential elements of bone. It is estimated that 1300g of calcium, 14g of magnesium, and 600g of phosphorus exist in bones of a 70-kg human adult.1 Basic structure of bone is composed of hydroxyapatite [Ca5(OH)(PO4)3], but Newman proposed that magnesium is incorporated in bone crystal in the following formula: [Ca9 ++(H2O+)2(PO4 ≡)6(OH−)2][Ca++ · Mg0.3 ++ · Na0.3 + · CO3 − · Cit0.3].2

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Author information

Authors and Affiliations

  1. Emeritus Professor Osaka City University, Osaka, Japan

    Hirotoshi Morii MD, PhD

  2. Pharmaceutical Division Pharmaceutical Development Laboratories, Pharmacology Group, Nephrology Kirin Brewery Co., Ltd, Takasaki, Japan

    Takehisa Kawata PhD

  3. Pharmaceutical Division Pharmaceutical Development Laboratories, Pharmacology Group, Nephrology Kirin Brewery Co., Ltd, Takasaki, Japan

    Nobuo Nagano PhD

  4. Central Research Laboratories, Nichinichi Pharmaceutical Co., Ltd, Mie, Japan

    Takashi Shimada PhD

  5. Central Research Laboratories, Nichinichi Pharmaceutical Co., Ltd, Mie, Japan

    Chie Motonaga

  6. Central Research Laboratories, Nichinichi Pharmaceutical Co., Ltd, Mie, Japan

    Mariko Okamori

  7. Central Research Laboratories, Nichinichi Pharmaceutical Co., Ltd, Mie, Japan

    Takao Nohmi

  8. Department of Geriatrics and Neurology, Graduate School of Osaka City University, Osaka, Japan

    Takami Miki MD, PhD

  9. Department of Pharmacology, Eisai Co., Ltd, Tokyo, Japan

    Masatoshi Kobayashi PhD

  10. Department of Pharmacology, Eisai Co., Ltd, Tokyo, Japan

    K. Hara

  11. Department of Pharmacology, Eisai Co., Ltd, Tokyo, Japan

    Y. Akiyama

Authors
  1. Hirotoshi Morii MD, PhD
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  2. Takehisa Kawata PhD
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  3. Nobuo Nagano PhD
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  4. Takashi Shimada PhD
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  5. Chie Motonaga
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  6. Mariko Okamori
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  7. Takao Nohmi
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  8. Takami Miki MD, PhD
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  9. Masatoshi Kobayashi PhD
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  10. K. Hara
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  11. Y. Akiyama
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Editor information

Editors and Affiliations

  1. Department of Metabolism, Endocrinology and Molecular Medicine, Osaka City University Graduate School of Medicine, Osaka, Japan

    Yoshiki Nishizawa MD, PhD (Dean of Medicine, Professor of Internal Medicine) (Dean of Medicine, Professor of Internal Medicine)

  2. Osaka City University, Osaka, Japan

    Hirotoshi Morii MD, PhD (Emeritus Professor) (Emeritus Professor)

  3. Université Pierre et Marie Curie, Paris, France

    Jean Durlach MD, PhD (President of the International Society for the Development of Research on Magnesium (SDRM), Editor-in-Chief Magnesium Research journal) (President of the International Society for the Development of Research on Magnesium (SDRM), Editor-in-Chief Magnesium Research journal)

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© 2007 Springer-Verlag London Limited

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Morii, H. et al. (2007). Magnesium and Osteoporosis. In: Nishizawa, Y., Morii, H., Durlach, J. (eds) New Perspectives in Magnesium Research. Springer, London. https://doi.org/10.1007/978-1-84628-483-0_21

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  • DOI: https://doi.org/10.1007/978-1-84628-483-0_21

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-84628-388-8

  • Online ISBN: 978-1-84628-483-0

  • eBook Packages: MedicineMedicine (R0)

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